DT-Web

DB07752 - FARNESYL


Identification
Name FARNESYL
Accession Number DB07752
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 206.3669
Groups experimental
Monoisotopic Weight 206.203450832
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Guanine nucleotide-binding protein G(T) subunit gamma-T1
Name Guanine nucleotide-binding protein G(T) subunit gamma-T1
Gene Name GNGT1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0528
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Name Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Gene Name GNB1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0515
Phosducin
Name Phosducin
Gene Name PDC
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.052
GTPase KRas
Name GTPase KRas
Gene Name KRAS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.371
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Name Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Gene Name FNTA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 2.2593
Protein farnesyltransferase subunit beta
Name Protein farnesyltransferase subunit beta
Gene Name FNTB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 2.2176
Geranylgeranyl transferase type-2 subunit alpha
Name Geranylgeranyl transferase type-2 subunit alpha
Gene Name RABGGTA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1598
Geranylgeranyl transferase type-2 subunit beta
Name Geranylgeranyl transferase type-2 subunit beta
Gene Name RABGGTB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1601
Rab proteins geranylgeranyltransferase component A 1
Name Rab proteins geranylgeranyltransferase component A 1
Gene Name CHM
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0513

Predictions


Id Partner name Gene Name Score
1994 Geranylgeranyl transferase type-1 subunit beta PGGT1B 0.4282
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.2641
853 Farnesyl pyrophosphate synthetase FDPS 0.2292
6595 Lantibiotic nisin-Z nisZ 0.2143
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.2139
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.2139
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.2139
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.2139
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.2139
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.2139
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.1862
5744 Undecaprenyl pyrophosphate synthetase uppS 0.1449
6589 Delta-hemolysin hld 0.0275
6424 Light-harvesting protein B-800/820 beta chain Not Available 0.0275
6586 Protein S100-G S100G 0.0275
6423 Light-harvesting protein B-800/820 alpha chain Not Available 0.0275
6587 Rubredoxin rub 0.0275
6591 ATP synthase C chain atpH 0.0275
6585 HLA class I histocompatibility antigen, B-27 alpha chain HLA-B 0.0274
4718 Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial CLPP 0.0274
6588 Methionyl-tRNA formyltransferase fmt 0.0274
6592 Probable L-ascorbate-6-phosphate lactonase ulaG ulaG 0.0274
6593 Immunoglobulin G-binding protein G spg 0.0274
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0239
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0239
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0239
6493 Cytochrome c oxidase subunit 6C COX6C 0.0239
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0239
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0239
6279 Beta-2-microglobulin B2M 0.0239
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0239
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0239
6319 Respiratory nitrate reductase 1 gamma chain narI 0.0239
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0239
6559 Cytochrome c oxidase subunit 2 ctaC 0.0239
6669 Cytochrome c oxidase subunit 2 ctaC 0.0239
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0239
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0239
3175 Glutamate--cysteine ligase gshA 0.0239
6318 Respiratory nitrate reductase 1 beta chain narH 0.0239
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0239
6558 Cytochrome c oxidase subunit 1 ctaD 0.0239
6317 Respiratory nitrate reductase 1 alpha chain narG 0.0238
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0221
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0221
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.022
2132 Protein S100-B S100B 0.0184
6351 Photosynthetic reaction center cytochrome c subunit pufC 0.0181
6353 Reaction center protein L chain pufL 0.0181
6454 Reaction center protein L chain pufL 0.0181
6683 Reaction center protein L chain pufL 0.0181
6354 Reaction center protein M chain pufM 0.0181
6455 Reaction center protein M chain pufM 0.0181
6684 Reaction center protein M chain pufM 0.0181
6352 Reaction center protein H chain puhA 0.0181
6456 Reaction center protein H chain puhA 0.0181
6682 Reaction center protein H chain puhA 0.0181
3027 Streptavidin Not Available 0.016
309 Antithrombin-III SERPINC1 0.0145
5682 Ribonuclease pancreatic RNASE1 0.0137
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0116
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