DT-Web

DB07544 - N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE


Identification
Name N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE
Accession Number DB07544
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 418.775
Groups experimental
Monoisotopic Weight 418.00018983
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Branched-chain-amino-acid aminotransferase, cytosolic
Name Branched-chain-amino-acid aminotransferase, cytosolic
Gene Name BCAT1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.3874

Predictions


Id Partner name Gene Name Score
246 Valyl-tRNA synthetase VARS 0.0711
6151 Monocarboxylate transporter 10 SLC16A10 0.0688
601 Propionyl-CoA carboxylase beta chain, mitochondrial PCCB 0.0573
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0535
701 Isoleucine-tRNA synthetase IARS 0.0405
4080 Isoleucyl-tRNA synthetase, mitochondrial IARS2 0.0405
546 Isoleucyl-tRNA synthetase, cytoplasmic IARS 0.0405
501 Leucine carboxyl methyltransferase 1 LCMT1 0.0347
675 Leucine carboxyl methyltransferase 2 LCMT2 0.0346
227 Probable leucyl-tRNA synthetase, mitochondrial LARS2 0.0346
846 Leucyl-tRNA synthetase, cytoplasmic LARS 0.0346
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0339
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0337
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0318
16 Adenosine A1 receptor ADORA1 0.0297
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0274
199 Monocarboxylate transporter 8 SLC16A2 0.0212
665 Phosphoserine aminotransferase PSAT1 0.0062
4652 Phosphoserine aminotransferase serC 0.0062
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0062
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0062
420 Glutamate decarboxylase 1 GAD1 0.0062
3900 Glutamate decarboxylase 1 GAD1 0.0062
3877 Growth-inhibiting protein 18 GIG18 0.0057
426 Aspartate aminotransferase, mitochondrial GOT2 0.0054
763 Tyrosine aminotransferase TAT 0.0053
5493 Tyrosine aminotransferase Not Available 0.0053
735 Alanine aminotransferase 1 GPT 0.0053
3904 Alanine aminotransferase 2 GPT2 0.0053
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0053
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0052
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0045
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0038
4026 Aspartyl aminopeptidase DNPEP 0.0038
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0038
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0038
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0038
1912 Excitatory amino acid transporter 1 SLC1A3 0.0038
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0038
4016 Excitatory amino acid transporter 5 SLC1A7 0.0038
4019 Excitatory amino acid transporter 4 SLC1A6 0.0038
1047 Excitatory amino acid transporter 2 SLC1A2 0.0038
664 Glutamate decarboxylase 2 GAD2 0.0038
3890 Glutamate decarboxylase 2 GAD2 0.0038
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0038
922 Glutamate receptor 4 GRIA4 0.0038
927 Metabotropic glutamate receptor 8 GRM8 0.0038
925 Metabotropic glutamate receptor 4 GRM4 0.0038
926 Metabotropic glutamate receptor 7 GRM7 0.0038
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0038
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0038
4020 Glutamyl aminopeptidase ENPEP 0.0038
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0038
4018 Glutamate receptor delta-2 subunit GRID2 0.0038
4027 Glutamate receptor delta-1 subunit GRID1 0.0038
4017 5-oxoprolinase OPLAH 0.0038
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0033
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0033
5 Glutaminase liver isoform, mitochondrial GLS2 0.0033
917 Glutaminase kidney isoform, mitochondrial GLS 0.0033
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0033
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0033
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0033
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0033
5261 Phosphoribosylformylglycinamidine synthase purL 0.0033
3881 Selenocysteine lyase variant Not Available 0.0033
3908 P-selectin cytoplasmic tail-associated protein pcap 0.0033
3891 Putative L-Dopa decarboxylase DDC 0.0033
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.0033
3883 Ornithine aminotransferase variant Not Available 0.0033
306 Pyridoxal phosphate phosphatase PDXP 0.0033
3880 Serine hydroxymethyltransferase 1 Not Available 0.0033
3911 Uncharacterized protein C20orf38 SPTLC3 0.0033
3906 Serine dehydratase-like SDSL 0.0033
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.0033
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.0033
3893 DDC protein DDC 0.0033
3887 Phosphorylase PYGB 0.0033
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.0033
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.0033
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.0033
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.0033
3886 Migration-inducing protein 4 ALAS1 0.0033
3878 GAD1 protein GAD1 0.0033
3894 KIAA0251 protein PDXDC1 0.0033
3875 Glycogen phosphorylase, brain form PYGB 0.0033
3882 Brain glycogen phosphorylase variant Not Available 0.0033
3905 Molybdenum cofactor sulfurase MOCOS 0.0033
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0032
534 Threonine synthase-like 1 THNSL1 0.0031
625 Glutamate carboxypeptidase 2 FOLH1 0.0031
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.003
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.003
184 L-serine dehydratase SDS 0.003
431 Serine racemase SRR 0.003
491 Serine palmitoyltransferase 1 SPTLC1 0.003
89 Cysteine sulfinic acid decarboxylase CSAD 0.003
727 Serine palmitoyltransferase 2 SPTLC2 0.003
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.003
499 Arginine decarboxylase ADC 0.003
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.003
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.003
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.003
1671 Excitatory amino acid transporter 3 SLC1A1 0.0029
3 Histidine decarboxylase HDC 0.0029
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0029
169 Cysteine desulfurase, mitochondrial NFS1 0.0029
916 Metabotropic glutamate receptor 1 GRM1 0.0028
435 Kynureninase KYNU 0.0028
4654 Kynureninase kynU 0.0028
3913 Glutamic acid decarboxylase GAD65 0.0028
472 Ornithine aminotransferase, mitochondrial OAT 0.0027
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0027
358 Cystathionine beta-synthase CBS 0.0027
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0027
923 Glutamate receptor 3 GRIA3 0.0027
3884 SHMT2 protein SHMT2 0.0027
3901 SHMT2 protein SHMT2 0.0027
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0027
3879 Serine hydroxymethyltransferase 2 Not Available 0.0027
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0027
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0027
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0026
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0026
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0026
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0026
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0026
868 Cystathionine gamma-lyase CTH 0.0025
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0025
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0025
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0025
349 Serine--pyruvate aminotransferase AGXT 0.0024
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0024
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0023
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0023
705 Glutamate receptor 1 GRIA1 0.0023
3426 Glutamine synthetase glnA 0.0023
3987 Glutamine synthetase GLUL 0.0023
449 Ornithine decarboxylase ODC1 0.0023
33 Cystine/glutamate transporter SLC7A11 0.0023
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0023
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0022
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0022
10 Glycogen phosphorylase, liver form PYGL 0.002
738 Monocarboxylate transporter 1 SLC16A1 0.0019
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0018
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0018
921 Glutamate receptor 2 GRIA2 0.0016
1152 Glycogen phosphorylase, muscle form PYGM 0.0015
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