DT-Web

DB07285 - (3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID


Identification
Name (3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID
Accession Number DB07285
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 294.272
Groups experimental
Monoisotopic Weight 294.037350594
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Matrix metalloproteinase-9
Name Matrix metalloproteinase-9
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.952

Predictions


Id Partner name Gene Name Score
707 72 kDa type IV collagenase MMP2 0.027
3090 Chitosanase csn 0.0267
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.0267
1253 Interferon gamma IFNG 0.023
777 Tumor necrosis factor TNF 0.0203
1729 Solute carrier family 22 member 6 SLC22A6 0.015
1654 Interleukin-1 beta IL1B 0.0149
244 Angiotensin-converting enzyme ACE 0.0141
494 Caspase-1 CASP1 0.0135
1507 Cytochrome c CYCS 0.0127
183 Vascular endothelial growth factor A VEGFA 0.012
2077 Caspase-3 CASP3 0.0116
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0108
6013 Cytochrome P450 2E1 CYP2E1 0.0104
22 30S ribosomal protein S4 rpsD 0.0103
6714 30S ribosomal protein S4 rpsD 0.0103
140 30S ribosomal protein S9 rpsI 0.0097
6719 30S ribosomal protein S9 rpsI 0.0097
6725 30S ribosomal protein S9 rpsI 0.0097
587 Serum albumin ALB 0.0093
6016 Cytochrome P450 2C19 CYP2C19 0.0092
275 Arachidonate 5-lipoxygenase ALOX5 0.0089
6201 Matrix metalloproteinase-27 MMP27 0.0087
6200 Matrix metalloproteinase-26 MMP26 0.0087
6197 Matrix metalloproteinase-23 MMP23A 0.0087
6199 Matrix metalloproteinase-25 MMP25 0.0087
6198 Matrix metalloproteinase-24 MMP24 0.0087
6192 Matrix metalloproteinase-15 MMP15 0.0087
6191 Matrix metalloproteinase-14 MMP14 0.0087
6196 Matrix metalloproteinase-21 MMP21 0.0087
6194 Matrix metalloproteinase-19 MMP19 0.0087
6193 Matrix metalloproteinase-17 MMP17 0.0087
6202 Matrix metalloproteinase-28 MMP28 0.0087
2970 Matrix metalloproteinase-16 MMP16 0.0085
6195 Matrix metalloproteinase-20 MMP20 0.0084
6188 Stromelysin-2 MMP10 0.0084
6190 Stromelysin-3 MMP11 0.0084
1588 Multidrug resistance protein 1 ABCB1 0.0078
6189 Matrilysin MMP7 0.0078
4119 Cytochrome P450 2D6 CYP2D6 0.0076
1167 Interstitial collagenase MMP1 0.0073
1024 Solute carrier family 22 member 11 SLC22A11 0.0072
6143 Solute carrier family 22 member 7 SLC22A7 0.007
6142 Solute carrier family 22 member 8 SLC22A8 0.0063
1330 Collagenase 3 MMP13 0.0062
2154 Neutrophil collagenase MMP8 0.0062
2203 Macrophage metalloelastase MMP12 0.006
1926 Stromelysin-1 MMP3 0.0057
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