DT-Web

DB04237 - Tris(Hydroxyethyl)Aminomethane


Identification
Name Tris(Hydroxyethyl)Aminomethane
Accession Number DB04237 (EXPT03004)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 163.2148
Groups experimental
Monoisotopic Weight 163.120843415
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Salivary alpha-amylase
Name Salivary alpha-amylase
Gene Name AMY1A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0391
Chlorocatechol 1,2-dioxygenase
Name Chlorocatechol 1,2-dioxygenase
Gene Name clcA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8092
Alpha-lytic protease
Name Alpha-lytic protease
Gene Name alpha-LP
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7536

Predictions


Id Partner name Gene Name Score
4513 Pancreatic alpha-amylase AMY2A 0.3318
3014 Ribonuclease UK114 HRSP12 0.0545
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.0544
3617 Non-heme chloroperoxidase cpo 0.0544
5426 Non-heme chloroperoxidase cpo 0.0544
3718 Hydrogen peroxide-inducible genes activator oxyR 0.0544
5428 Replication protein repA 0.0544
3018 HTH-type transcriptional regulator malT malT 0.0543
3115 Ras-related protein Rab-9 RAB9A 0.0474
2958 Probable tautomerase ydcE pptA 0.0474
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0474
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0474
2573 Cocaine esterase cocE 0.0473
7263 Cocaine esterase Not Available 0.0473
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0377
2693 Heat-labile enterotoxin B chain eltB 0.0369
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0368
6645 D-amino-acid oxidase DAO 0.0359
5012 Ig lambda chain V-II region MGC Not Available 0.0336
4385 Cytochrome c' Not Available 0.0336
4967 Cytochrome c' cycA 0.0336
5038 Cytochrome c' Not Available 0.0336
5223 Cytochrome c' cycP 0.0336
5036 Small inducible cytokine A8 CCL8 0.0336
5006 RNASE4 protein RNASE4 0.0293
5023 Glycoside hydrolase Not Available 0.0292
5024 Glycoside hydrolase Not Available 0.0292
4771 Dissimilatory copper-containing nitrite reductase nir 0.0292
2149 Angiogenin ANG 0.027
4905 Cytochrome c2 Not Available 0.027
4939 Cytochrome c2 cycA 0.027
4964 Cytochrome c2 cycA 0.027
4979 Cytochrome c2 cycA 0.027
6673 Cytochrome c2 cycA 0.027
2430 Chondroitinase B cslB 0.0253
738 Monocarboxylate transporter 1 SLC16A1 0.0235
6374 Disintegrin and metalloproteinase domain-containing protein 28 ADAM28 0.0227
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0204
183 Vascular endothelial growth factor A VEGFA 0.0187
6142 Solute carrier family 22 member 8 SLC22A8 0.0159
3689 Endoglucanase A celA 0.0057
5411 Slt-IIvB stxB2e 0.0057
5046 Ecotin eco 0.0057
5563 Galectin-2 LGALS2 0.0057
3009 Beta-glucanase Not Available 0.0057
5569 Endo-1,4-beta glucanase EngF engF 0.0057
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0057
5554 D-galactose-binding periplasmic protein mglB 0.0057
3741 D-galactose-binding periplasmic protein precursor mglB 0.0057
5553 Endoglucanase E1 Acel_0614 0.0057
1875 Pulmonary surfactant-associated protein D SFTPD 0.0057
4668 Laminarinase TM_0024 0.0057
5562 Hexokinase Not Available 0.0057
3744 Endoglucanase SS precursor celS 0.0057
3793 Aspartate ammonia-lyase aspA 0.0057
5559 Neopullulanase nplT 0.0057
5568 Endoglucanase C307 celC307 0.0057
4670 Cellulase B celB 0.0057
5570 Endoglucanase E-4 celD 0.0057
4667 BH0236 protein BH0236 0.0057
4671 Endoglucanase C cenC 0.0057
1503 Galectin-7 LGALS7 0.0049
4509 Acetoin(diacetyl) reductase budC 0.0049
4622 Amylase Not Available 0.0049
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0049
1184 Interferon beta IFNB1 0.0049
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0049
5416 Coat protein VP1 Not Available 0.0049
5247 Endo-1,4-beta-xylanase Not Available 0.0049
5248 Endo-1,4-beta-xylanase xlnA 0.0049
5250 Endo-1,4-beta-xylanase xyl 0.0049
5176 YtnJ moxC 0.0049
5498 Maltoporin lamB 0.0049
5561 Maltoporin lamB 0.0049
4669 Endo-1,4-beta-xylanase A xynA 0.0049
4715 Endo-1,4-beta-xylanase A xlnA 0.0049
5560 Endo-1,4-beta-xylanase A xynA 0.0049
2705 Dimethyl sulfoxide reductase dmsA 0.0049
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0049
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0045
2531 Alpha-amylase amyE 0.0045
2948 Alpha-amylase amy 0.0045
3169 Alpha-amylase Not Available 0.0045
4819 Hydrolase Not Available 0.0045
5249 Hydrolase Not Available 0.0045
5436 Hydrolase Not Available 0.0045
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0045
3747 Cellulase B precursor celB 0.0045
3547 Enterotoxin type B entB 0.0045
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0045
2606 Neopullulanase 2 tvaII 0.0045
4811 Amylosucrase ams 0.0045
2541 Neopullulanase 1 tvaI 0.0045
3091 Maltodextrin phosphorylase malP 0.0045
2324 Botulinum neurotoxin type B botB 0.0045
3225 Shiga toxin B-chain stxB 0.0043
4666 Fucose-binding lectin PA-IIL lecB 0.0043
2826 Glucose--fructose oxidoreductase gfo 0.0043
4830 Aldose 1-epimerase galM 0.0043
2372 Bifunctional tail protein 9 0.0043
3365 Beta-amylase spoII 0.0043
1881 Hexokinase-1 HK1 0.0043
1675 Glucokinase GCK 0.0041
4662 Glucokinase glk 0.0041
6614 Lactase-like protein LCTL 0.0041
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0041
2508 Cyclomaltodextrin glucanotransferase cgt 0.0041
2523 Cyclomaltodextrin glucanotransferase cgt 0.0041
3207 Cyclomaltodextrin glucanotransferase amyA 0.0041
3668 Maltose-binding periplasmic protein precursor malE 0.004
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.004
2802 Endoglucanase G celCCG 0.004
2570 Tetanus toxin tetX 0.004
4692 A/G-specific adenine glycosylase mutY 0.0039
4272 POSSIBLE CELLULASE CELA1 celA1 0.0039
2440 Endoglucanase F celCCF 0.0037
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0036
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0036
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0036
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0036
2245 Xylose isomerase xylA 0.0034
2253 Xylose isomerase xylA 0.0034
2260 Xylose isomerase xylA 0.0034
2431 Xylose isomerase xylA 0.0034
2252 Endoglucanase 5A cel5A 0.0034
2723 Cholera enterotoxin subunit B ctxB 0.0033
10 Glycogen phosphorylase, liver form PYGL 0.0032
2427 Ferrichrome-iron receptor fhuA 0.0032
1152 Glycogen phosphorylase, muscle form PYGM 0.0026
20 Prostaglandin G/H synthase 1 PTGS1 0.0016
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