DT-Web

DB03961 - 2c-Methyl-D-Erythritol 2,4-Cyclodiphosphate


Identification
Name 2c-Methyl-D-Erythritol 2,4-Cyclodiphosphate
Accession Number DB03961 (EXPT00871)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 278.0909
Groups experimental
Monoisotopic Weight 277.995655006
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Name 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Gene Name ispF
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.918

Predictions


Id Partner name Gene Name Score
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.918
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.918
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.918
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.918
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.918
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.1179
3019 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ispD 0.1089
3344 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ispD 0.1089
3188 IspD/ispF bifunctional enzyme [Includes: 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase ispDF 0.0907
2909 Cytidylate kinase cmk 0.0856
2765 3-deoxy-manno-octulosonate cytidylyltransferase kpsU 0.0819
3120 3-deoxy-manno-octulosonate cytidylyltransferase kdsB 0.0819
2944 N-acylneuraminate cytidylyltransferase neuA 0.0678
7074 N-acylneuraminate cytidylyltransferase CMAS 0.0678
2967 CDP-paratose 2-epimerase rfbE 0.059
6596 Short-chain Z-isoprenyl diphosphate synthetase Rv1086 0.0506
3779 Alpha-2,3/8-sialyltransferase cst-II 0.0452
6540 Prenyltransferase Not Available 0.044
3692 Coenzyme A biosynthesis bifunctional protein coaBC coaBC 0.0393
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.0343
2697 Uridine-cytidine kinase 2 UCK2 0.0316
853 Farnesyl pyrophosphate synthetase FDPS 0.0299
702 UMP-CMP kinase CMPK1 0.0283
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