DT-Web

DB03766 - Propanoic Acid


Identification
Name Propanoic Acid
Accession Number DB03766 (EXPT02641)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 74.0785
Groups experimental
Monoisotopic Weight 74.036779436
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Non-heme chloroperoxidase
Name Non-heme chloroperoxidase
Gene Name cpo
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8097
Gephyrin
Name Gephyrin
Gene Name GPHN
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7067
Hypothetical protein
Name Hypothetical protein
Gene Name PA3967
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.02
2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase
Name 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase
Gene Name cumD
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.586
Alanine racemase
Name Alanine racemase
Gene Name alr
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4626

Carriers


Predictions


Id Partner name Gene Name Score
894 Alanine racemase alr 1.4626
5426 Non-heme chloroperoxidase cpo 0.8097
2249 Aspartate aminotransferase aspC 0.131
2671 Aspartate aminotransferase aspC 0.131
5490 Aspartate aminotransferase Not Available 0.131
2749 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase arnB 0.1218
5358 Aminodeoxychorismate lyase pabC 0.1076
3526 Pseudomonalisin pcp 0.0961
4802 L-cysteine/cystine lyase C-DES c-des 0.0937
4819 Hydrolase Not Available 0.073
5249 Hydrolase Not Available 0.073
5436 Hydrolase Not Available 0.073
3089 Lipase 1 LIP1 0.073
6258 Protein S100-A7 S100A7 0.0549
2853 14 kDa fatty acid-binding protein Not Available 0.0487
520 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0383
2306 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0383
2367 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0383
3923 Cholinesterase BCHE 0.0374
2211 Fatty acid-binding protein, heart FABP3 0.0328
2744 D-alanine aminotransferase dat 0.0323
3237 Beta-lactamase OXA-2 bla 0.0322
4924 Cytochrome P450 2C8 CYP2C8 0.0319
6677 Myelin P2 protein PMP2 0.0307
2746 4-aminobutyrate aminotransferase gabT 0.0281
2842 Glutamate-1-semialdehyde 2,1-aminomutase hemL 0.0281
6085 Fatty acid-binding protein, intestinal FABP2 0.0262
2546 Histidinol-phosphate aminotransferase hisC 0.0259
2698 Histidinol-phosphate aminotransferase hisC 0.0259
373 Transthyretin TTR 0.0239
587 Serum albumin ALB 0.0217
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0204
4545 Molybdopterin-converting factor subunit 2 moaE 0.02
4514 Citrate lyase beta subunit-like protein citE 0.02
4781 Citrate lyase beta subunit-like protein DR_1240 0.02
3014 Ribonuclease UK114 HRSP12 0.02
4037 Hypothetical protein GPX1 0.02
4297 Hypothetical protein SP_1951 0.02
4521 Hypothetical protein BC_2969 0.02
4540 Hypothetical protein TM_1070 0.02
4555 Hypothetical protein MT1739 0.02
4569 Hypothetical protein mshD 0.02
4578 Hypothetical protein PA3270 0.02
5177 Hypothetical protein TM_0096 0.02
5194 Hypothetical protein PA1204 0.02
5240 Hypothetical protein Rv2991 0.02
5370 Hypothetical protein TM_1158 0.02
5710 Hypothetical protein Tb927.5.1360 0.02
4524 Mannose-6-phosphate isomerase yvyI 0.02
4106 Guanylate kinase GUK1 0.02
4516 Guanylate kinase gmk 0.02
4522 Arginine N-succinyltransferase subunit alpha astA 0.02
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.02
4527 Putative hydrolase ycdX ycdX 0.02
4536 Transcriptional regulator, IclR family TM_0065 0.02
3718 Hydrogen peroxide-inducible genes activator oxyR 0.02
2501 Protein ygbM ygbM 0.02
4547 Iron binding protein FbpA fbpA 0.02
658 Para-aminobenzoate synthase component 1 pabB 0.02
4538 Hypothetical protein VC1899 VC_1899 0.02
4529 Oxalate decarboxylase oxdC oxdC 0.02
5428 Replication protein repA 0.02
4548 Gyrase B gyrB 0.02
4546 Aminotransferase, putative TM_1131 0.02
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0199
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0199
4515 Peripheral plasma membrane protein CASK CASK 0.0199
3018 HTH-type transcriptional regulator malT malT 0.0199
6501 Fatty acid-binding protein, liver FABP1 0.0185
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.018
2958 Probable tautomerase ydcE pptA 0.0174
2929 (S)-2-haloacid dehalogenase dhlB 0.0174
2995 (S)-2-haloacid dehalogenase Not Available 0.0174
4533 Glyoxalase family protein BC_1747 0.0174
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0174
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0174
4528 Phenazine biosynthesis protein PhzD phzD1 0.0174
3759 Glutathione S-transferase gst 0.0174
4541 Glutathione S-transferase GST 0.0174
3115 Ras-related protein Rab-9 RAB9A 0.0174
4542 Glutaminase 1 glsA1 0.0174
4544 Glutaminase 1 glsA1 0.0174
56 Delta-aminolevulinic acid dehydratase ALAD 0.0174
2356 Delta-aminolevulinic acid dehydratase hemB 0.0174
3613 Delta-aminolevulinic acid dehydratase hemB 0.0174
3674 Delta-aminolevulinic acid dehydratase hemB 0.0174
4517 Probable butyrate kinase 2 buk2 0.0174
3261 Signal recognition particle protein ffh 0.0174
4496 C-terminal-binding protein 1 CTBP1 0.0174
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0174
2573 Cocaine esterase cocE 0.0174
7263 Cocaine esterase Not Available 0.0174
3382 Glycolipid transfer protein GLTP 0.017
3122 D-hydantoinase Not Available 0.017
3145 D-hydantoinase hyuA 0.017
3168 Beta-lactamase OXA-1 bla 0.017
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.017
4602 Osmotically inducible protein C tthHB8IM 0.0169
2664 S-ribosylhomocysteine lyase luxS 0.0169
2725 S-ribosylhomocysteine lyase luxS 0.0169
2670 Pyridoxamine kinase pdxY 0.0169
810 Heme oxygenase 1 HMOX1 0.0167
3391 Heme oxygenase 1 pbsA1 0.0167
3467 Methylglyoxal synthase mgsA 0.016
3583 6-phosphogluconolactonase pgl 0.016
4531 Putative ketoacyl reductase actIII 0.016
2775 Dihydroorotate dehydrogenase pyrD 0.016
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0151
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0151
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.015
3292 Alanine racemase, catabolic dadX 0.0148
4264 Alpha-L-fucosidase, putative TM_0306 0.0148
3281 Isoaspartyl dipeptidase iadA 0.0148
3616 Fatty acid-binding protein, epidermal FABP5 0.0147
3599 Peroxiredoxin-2 PRDX2 0.0147
4601 HMG-CoA synthase mvaS 0.0147
2378 Carboxymethylenebutenolidase clcD 0.0147
2705 Dimethyl sulfoxide reductase dmsA 0.0147
5431 Lipid binding protein Not Available 0.0146
5433 UPF0230 protein TM_1468 TM_1468 0.0146
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0146
1992 Vitamin D-binding protein GC 0.0145
76 Nitric-oxide synthase, brain NOS1 0.0145
2688 Peptide deformylase def 0.0145
2708 Peptide deformylase def 0.0145
3004 Peptide deformylase def 0.0145
4337 Peptide deformylase def 0.0145
4338 Peptide deformylase def 0.0145
5368 Peptide deformylase def 0.0145
5371 Peptide deformylase def 0.0145
6375 Peptide deformylase def 0.0145
6378 Peptide deformylase def 0.0145
6379 Peptide deformylase def 0.0145
6776 Peptide deformylase def 0.0145
6900 Peptide deformylase def 0.0145
4534 Cytohesin-2 CYTH2 0.0145
3312 Fatty acid-binding protein, brain FABP7 0.0143
2548 Subtilisin Carlsberg apr 0.0139
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0139
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0136
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0136
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0136
2714 Chorismate mutase aroH 0.0136
4611 Chorismate mutase aroG 0.0136
2603 Beta-lactamase II blm 0.0135
2693 Heat-labile enterotoxin B chain eltB 0.0135
6645 D-amino-acid oxidase DAO 0.0132
4549 Endonuclease III HP_0602 0.0129
2646 Dihydroorotase pyrC 0.0129
4600 Malonamidase E2 Not Available 0.0128
2717 Folylpolyglutamate synthase fgs 0.0123
20 Prostaglandin G/H synthase 1 PTGS1 0.0119
760 Fibroblast growth factor 1 FGF1 0.0117
6459 Glycodelin PAEP 0.0117
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0117
3027 Streptavidin Not Available 0.0116
2340 Beta-lactamase PSE-2 bla 0.0116
2796 Parathion hydrolase opd 0.0115
6539 Parathion hydrolase opd 0.0115
500 Monocarboxylate transporter 4 SLC16A3 0.0114
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0109
283 SEC14-like protein 2 SEC14L2 0.0104
5682 Ribonuclease pancreatic RNASE1 0.01
4757 Cytochrome P450 2C9 CYP2C9 0.0091
714 Glutathione reductase, mitochondrial GSR 0.0089
738 Monocarboxylate transporter 1 SLC16A1 0.0088
4954 Soluble cytochrome b558 Not Available 0.0085
4934 Cytochrome c-551 nirM 0.0085
5218 Cytochrome c-551 nirM 0.0085
4916 Cyanoglobin glbN 0.0085
4994 Hemoglobin-like protein HbO glbO 0.0085
4975 Cytochrome c-556 RPA3973 0.0085
4943 Cytochrome c6 petJ 0.0085
4905 Cytochrome c2 Not Available 0.0085
4939 Cytochrome c2 cycA 0.0085
4964 Cytochrome c2 cycA 0.0085
4979 Cytochrome c2 cycA 0.0085
6673 Cytochrome c2 cycA 0.0085
4936 Cytochrome c2 iso-2 Not Available 0.0085
4915 Cytochrome c-550 psbV 0.0085
4959 Cytochrome c-550 psbV 0.0085
5216 Cytochrome c-550 psbV 0.0085
4925 Cytochrome c-type protein SHP shp 0.0085
5000 HemO hemO 0.0085
4998 Hemoglobin-like protein yjbI yjbI 0.0085
4947 Bacterial hemoglobin vhb 0.0085
4942 Diheme cytochrome c napB napB 0.0085
4984 Neuroglobin NGB 0.0085
3116 Bacterioferritin bfr 0.0085
4906 Bacterioferritin bfr 0.0085
4965 Bacterioferritin bfr 0.0085
4971 Nonaheme cytochrome c hmcA 0.0085
4961 Hemophore HasA hasA 0.0085
4910 Cytoglobin CYGB 0.0085
4907 Cytochrome c-L moxG 0.0085
6865 Cytochrome c-L moxG 0.0085
4981 Iron-starvation protein PigA pigA 0.0085
4909 CooA protein cooA 0.0085
4999 Cytochrome P450 165B3 CYP165B3 0.0085
4935 Cytochrome c-554 cycA1 0.0085
4931 Cytochrome P450 167A1 CYP167A1 0.0085
644 Heme oxygenase 2 HMOX2 0.0085
4982 Heme oxygenase 2 pbsA2 0.0085
4937 Cytochrome oxidase subunit II rcoxA 0.0085
4989 Cytochrome c551 peroxidase ccp 0.0085
5222 Cytochrome c551 peroxidase ccpA 0.0085
4976 Apocytochrome f petA 0.0085
6407 Apocytochrome f petA 0.0085
4904 Cytochrome c family protein GSU1996 0.0085
4972 P450cin cinA 0.0085
4764 Cytochrome P450 165C4 CYP165C4 0.0085
4960 Putative cytochrome P450-family protein SCO7417 0.0085
3093 Catalase HPII katE 0.0085
4903 Methyl-accepting chemotaxis protein Tar4 0.0085
4926 Heme-based aerotactic transducer hemAT hemAT 0.0085
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0085
4922 Cytochrome c, putative SO_4144 0.0085
4952 Catalase/peroxidase katA 0.0085
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0085
4993 Hydroxylamine oxidoreductase hao1 0.0085
2207 Rhodopsin RHO 0.0081
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0075
4990 PpcA ppcA 0.0074
4948 Cytochrome c-553 Not Available 0.0074
3375 Acidic cytochrome c3 Not Available 0.0074
4385 Cytochrome c' Not Available 0.0074
4967 Cytochrome c' cycA 0.0074
5038 Cytochrome c' Not Available 0.0074
5223 Cytochrome c' cycP 0.0074
4923 Cytochrome c3 DvMF_2499 0.0074
4945 Cytochrome c3 Not Available 0.0074
4949 Cytochrome c3 DVU_3171 0.0074
4968 Cytochrome c3 cytc3 0.0074
4997 Cytochrome c3 SO_2727 0.0074
5219 Cytochrome c3 cyd 0.0074
2119 Cytochrome b5 CYB5A 0.0074
4992 Cytochrome c peroxidase Not Available 0.0074
4813 Heme oxygenase hmuO 0.0074
5769 Heme oxygenase Not Available 0.0074
2915 Sensor protein fixL fixL 0.0074
4944 Sensor protein fixL fixL 0.0074
4902 Nine-heme cytochrome c Ddes_2038 0.0074
4289 Cytochrome P450 TT_P0059 0.0074
6262 Cytochrome P450 staP 0.0074
3570 Cytochrome P450 152A1 cypC 0.0074
4920 Peroxidase/catalase katG 0.0074
4988 Sulfite oxidase, mitochondrial SUOX 0.0074
3189 High-molecular-weight cytochrome c hmcA 0.0074
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0074
357 Carbonic anhydrase 2 CA2 0.0073
3670 Soluble cytochrome b562 precursor cybC 0.0069
3291 Cytochrome c-552 cycA 0.0069
4927 Cytochrome c-552 nrfA 0.0069
4938 Cytochrome c-552 cycA 0.0069
4953 Cytochrome c-552 nrfA 0.0069
5217 Cytochrome c-552 cycM 0.0069
4386 Hemoglobin-like protein HbN glbN 0.0069
3411 Cytochrome P450 121 cyp121 0.0068
3102 Flavohemoprotein hmp 0.0068
4969 Flavohemoprotein hmp 0.0068
2617 Nitric oxide synthase oxygenase nos 0.0068
2701 Nitric oxide synthase oxygenase nos 0.0068
2230 Catalase CAT 0.0066
3249 Catalase katA 0.0066
3625 Catalase katA 0.0066
4539 Catalase katA 0.0066
4941 Catalase katB 0.0066
3221 Cytochrome c4 cc4 0.0065
3127 Nitrite reductase nirS 0.0064
3284 Nitrite reductase nirS 0.0064
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0064
2240 Cell division protein kinase 2 CDK2 0.0064
4608 Putative cytochrome P450 SCO1207 0.0062
4963 Putative cytochrome P450 SCO2884 0.0062
6254 Putative cytochrome P450 SCO6998 0.0062
605 Fumarate reductase flavoprotein subunit frdA 0.0061
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0061
3673 Fumarate reductase flavoprotein subunit fccA 0.0061
4912 Fumarate reductase flavoprotein subunit ifcA 0.0061
6549 Fumarate reductase flavoprotein subunit frdA 0.0061
2972 6-deoxyerythronolide B hydroxylase eryF 0.0061
518 Peroxidase/catalase T katG 0.0059
6142 Solute carrier family 22 member 8 SLC22A8 0.0058
260 Cytochrome P450 51 ERG11 0.0058
761 Cytochrome P450 51 ERG11 0.0058
3163 Cytochrome P450 51 cyp51 0.0058
1507 Cytochrome c CYCS 0.0056
358 Cystathionine beta-synthase CBS 0.0055
693 Hemoglobin subunit beta HBB 0.0054
6268 Hydroxyacid oxidase 1 HAO1 0.0054
2298 Cytochrome P450-cam camC 0.0047
275 Arachidonate 5-lipoxygenase ALOX5 0.0042
7 Nitric oxide synthase, inducible NOS2 0.004
291 Nitric-oxide synthase, endothelial NOS3 0.0039
6106 Cytochrome P450 2C18 CYP2C18 0.0035
1588 Multidrug resistance protein 1 ABCB1 0.0033
290 Prostaglandin G/H synthase 2 PTGS2 0.0031
6030 Cytochrome P450 2B6 CYP2B6 0.0027
4512 Cytochrome P450 3A4 CYP3A4 0.002
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