DT-Web

DB03141 - 3-({5-Benzyl-6-Hydroxy-2,4-Bis-(4-Hydroxy-Benzyl)-3-Oxo-[1,2,4]-Triazepane-1-Sulfonyl)-Benzonitrile


Identification
Name 3-({5-Benzyl-6-Hydroxy-2,4-Bis-(4-Hydroxy-Benzyl)-3-Oxo-[1,2,4]-Triazepane-1-Sulfonyl)-Benzonitrile
Accession Number DB03141 (EXPT00690)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 598.669
Groups experimental
Monoisotopic Weight 598.188605402
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Gag-Pol polyprotein
Name Gag-Pol polyprotein
Gene Name gag-pol
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0359
V-1 protease
Name V-1 protease
Gene Name ORF
Pharmacological action unknown
Actions Not Available
References
  • Huang PP, Randolph JT, Klein LL, Vasavanonda S, Dekhtyar T, Stoll VS, Kempf DJ: Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors. Bioorg Med Chem Lett. 2004 Aug 2;14(15):4075-8. - Pubmed
DTHybrid score 1.0409

Predictions


Id Partner name Gene Name Score
4623 Protease PROF 0.0405
4821 Protease pol 0.0405
5748 Protease pol 0.0405
6733 Protease pol 0.0405
864 Gag-Pol polyprotein gag-pol 0.0359
2237 Gag-Pol polyprotein gag-pol 0.0359
2326 Gag-Pol polyprotein gag-pol 0.0359
2451 Gag-Pol polyprotein gag-pol 0.0359
2901 Gag-Pol polyprotein gag-pol 0.0359
3165 Gag-Pol polyprotein gag-pol 0.0359
6306 Gag-Pol polyprotein gag-pol 0.0359
6624 Gag-Pol polyprotein gag-pol 0.0359
2555 Pol polyprotein pol 0.0274
3242 Pol polyprotein gag-pol 0.0274
3471 Pol polyprotein gag-pro-pol 0.0274
5256 Pol polyprotein pol 0.0274
6469 Pol polyprotein gag-pol 0.0274
6565 Pol polyprotein Not Available 0.0274
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