DT-Web

DB02381 - Nor-N-Omega-Hydroxy-L-Arginine


Identification
Name Nor-N-Omega-Hydroxy-L-Arginine
Accession Number DB02381 (EXPT02371)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 176.1738
Groups experimental
Monoisotopic Weight 176.09094027
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Arginase-1
Name Arginase-1
Gene Name ARG1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2885

Predictions


Id Partner name Gene Name Score
834 Arginase-2, mitochondrial ARG2 0.0915
3627 UPF0190 protein yedY yedY 0.0376
1392 Catenin beta-1 CTNNB1 0.0375
3352 Structural polyprotein Not Available 0.0375
3628 Structural polyprotein Not Available 0.0375
4892 Structural polyprotein Not Available 0.0375
2617 Nitric oxide synthase oxygenase nos 0.0369
2701 Nitric oxide synthase oxygenase nos 0.0369
365 Dihydrofolate reductase DHFR 0.0255
2381 Dihydrofolate reductase DFR1 0.0255
2833 Dihydrofolate reductase Not Available 0.0255
2931 Dihydrofolate reductase folA 0.0255
3544 Dihydrofolate reductase folA 0.0255
3682 Dihydrofolate reductase folA 0.0255
6642 Dihydrofolate reductase folA 0.0255
6756 Dihydrofolate reductase dfrA 0.0255
76 Nitric-oxide synthase, brain NOS1 0.0231
7 Nitric oxide synthase, inducible NOS2 0.0207
291 Nitric-oxide synthase, endothelial NOS3 0.0206
5691 DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC rmlC 0.0152
5694 Transcription antiterminator licT licT 0.0152
3361 Serpin B5 SERPINB5 0.0152
357 Carbonic anhydrase 2 CA2 0.0139
3981 Ornithine decarboxylase antizyme 3 OAZ3 0.0127
3980 Ornithine decarboxylase antizyme 2 OAZ2 0.0127
410 Ornithine decarboxylase antizyme OAZ1 0.0126
224 Mitochondrial ornithine transporter 1 SLC25A15 0.0126
285 Mitochondrial ornithine transporter 2 SLC25A2 0.0126
56 Delta-aminolevulinic acid dehydratase ALAD 0.0122
2356 Delta-aminolevulinic acid dehydratase hemB 0.0122
3613 Delta-aminolevulinic acid dehydratase hemB 0.0122
3674 Delta-aminolevulinic acid dehydratase hemB 0.0122
2286 Isocitrate dehydrogenase [NADP] icd 0.0115
2302 Isocitrate dehydrogenase [NADP] icd 0.0115
2771 Isocitrate dehydrogenase [NADP] icd 0.0115
4534 Cytohesin-2 CYTH2 0.0109
619 Low-affinity cationic amino acid transporter 2 SLC7A2 0.0109
336 Ornithine carbamoyltransferase, mitochondrial OTC 0.0108
3668 Maltose-binding periplasmic protein precursor malE 0.0105
383 Glycine amidinotransferase, mitochondrial GATM 0.0105
472 Ornithine aminotransferase, mitochondrial OAT 0.0104
150 Cationic amino acid transporter 3 SLC7A3 0.01
235 High-affinity cationic amino acid transporter 1 SLC7A1 0.01
58 Cationic amino acid transporter 4 SLC7A4 0.01
2592 Beta-galactosidase lacZ 0.0093
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0082
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.008
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0071
24 Thymidylate synthase TMP1 0.0066
359 Thymidylate synthase TYMS 0.0066
2626 Thymidylate synthase thyA 0.0066
2729 Thymidylate synthase thyA 0.0066
5352 Thymidylate synthase THYA 0.0066
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0063
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