DT-Web

DB02097 - Cytidine


Identification
Name Cytidine
Accession Number DB02097 (EXPT01051)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 243.2166
Groups experimental
Monoisotopic Weight 243.085520541
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Uridine-cytidine kinase 2
Name Uridine-cytidine kinase 2
Gene Name UCK2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5315

Predictions


Id Partner name Gene Name Score
2297 Genome polyprotein Not Available 0.1177
2322 Genome polyprotein Not Available 0.1177
2694 Genome polyprotein Not Available 0.1177
2719 Genome polyprotein Not Available 0.1177
2860 Genome polyprotein Not Available 0.1177
2928 Genome polyprotein Not Available 0.1177
3160 Genome polyprotein Not Available 0.1177
3260 Genome polyprotein Not Available 0.1177
4783 Genome polyprotein Not Available 0.1177
5726 Genome polyprotein Not Available 0.1177
5779 Genome polyprotein Not Available 0.1177
5867 Genome polyprotein Not Available 0.1177
6253 Genome polyprotein Not Available 0.1177
6301 Genome polyprotein Not Available 0.1177
6380 Genome polyprotein Not Available 0.1177
6381 Genome polyprotein Not Available 0.1177
6437 Genome polyprotein Not Available 0.1177
6520 Genome polyprotein Not Available 0.1177
6521 Genome polyprotein Not Available 0.1177
6652 Genome polyprotein Not Available 0.1177
6734 Genome polyprotein Not Available 0.1177
6735 Genome polyprotein Not Available 0.1177
6736 Genome polyprotein Not Available 0.1177
6737 Genome polyprotein Not Available 0.1177
6738 Genome polyprotein Not Available 0.1177
6739 Genome polyprotein Not Available 0.1177
6744 Genome polyprotein Not Available 0.1177
6748 Genome polyprotein Not Available 0.1177
6894 Genome polyprotein Not Available 0.1177
6898 Genome polyprotein Not Available 0.1177
3692 Coenzyme A biosynthesis bifunctional protein coaBC coaBC 0.0836
2765 3-deoxy-manno-octulosonate cytidylyltransferase kpsU 0.0695
3120 3-deoxy-manno-octulosonate cytidylyltransferase kdsB 0.0695
4677 Glucose-1-phosphate cytidylyltransferase rfbF 0.0508
4676 CCA-adding enzyme cca 0.0508
3779 Alpha-2,3/8-sialyltransferase cst-II 0.0452
2991 Glycerol-3-phosphate cytidylyltransferase tagD 0.0442
3019 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ispD 0.0408
3344 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ispD 0.0408
3188 IspD/ispF bifunctional enzyme [Includes: 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase ispDF 0.0393
2909 Cytidylate kinase cmk 0.0342
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0316
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0316
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0316
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0316
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0316
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0316
702 UMP-CMP kinase CMPK1 0.0314
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0077
5590 N utilization substance protein B homolog nusB 0.0064
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0064
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0064
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0064
5582 Regulator of transcription; stringent starvation protein A sspA 0.0064
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0064
2838 Ribose-5-phosphate isomerase A rpiA 0.0064
2952 Ribose-5-phosphate isomerase A rpiA 0.0064
5595 Ribose-5-phosphate isomerase A rpiA 0.0064
4238 50S ribosomal protein L4 rplD 0.0064
5578 50S ribosomal protein L4 rplD 0.0064
6173 50S ribosomal protein L4 rplD 0.0064
6219 50S ribosomal protein L4 rplD 0.0064
4695 UPF0124 protein yfiH yfiH 0.0064
5581 Beta-fructosidase bfrA 0.0064
5588 Cell division protein FtsY TM_0570 0.0064
5060 Intron-associated endonuclease 1 ITEVIR 0.0064
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0064
2300 Lysozyme E 0.0064
3633 Lysozyme R 0.0064
5597 Lysozyme 17 0.0064
5587 Iron(III)-binding periplasmic protein fbpA 0.0064
5591 Complement component C8 gamma chain C8G 0.0063
4375 Glutamine synthetase 1 glnA1 0.0063
5575 Short tail fiber protein 12 0.0063
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0063
5593 Transferase Not Available 0.0063
5580 Hexon protein PII 0.0063
5574 Invasin YPTB1668 0.0063
5600 Pyruvate decarboxylase pdc 0.0063
4533 Glyoxalase family protein BC_1747 0.0055
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0055
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0055
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0055
5006 RNASE4 protein RNASE4 0.0055
3132 Tryptophan synthase alpha chain trpA 0.0055
6568 Tryptophan synthase alpha chain trpA 0.0055
5328 Prostaglandin F synthase Tb11.02.2310 0.0055
4992 Cytochrome c peroxidase Not Available 0.0055
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0055
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0055
3729 Citrate synthase gltA 0.0055
4575 Citrate synthase cit 0.0055
4580 Citrate synthase gltA 0.0055
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0055
2555 Pol polyprotein pol 0.0055
3242 Pol polyprotein gag-pol 0.0055
3471 Pol polyprotein gag-pro-pol 0.0055
5256 Pol polyprotein pol 0.0055
6469 Pol polyprotein gag-pol 0.0055
6565 Pol polyprotein Not Available 0.0055
5682 Ribonuclease pancreatic RNASE1 0.0051
2603 Beta-lactamase II blm 0.0051
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0051
3583 6-phosphogluconolactonase pgl 0.0051
2149 Angiogenin ANG 0.0051
2521 Cell division protein ftsZ ftsZ 0.0051
3301 Cell division protein ftsZ ftsZ 0.0051
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0051
857 Malate dehydrogenase, mitochondrial MDH2 0.0048
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0048
2286 Isocitrate dehydrogenase [NADP] icd 0.0048
2302 Isocitrate dehydrogenase [NADP] icd 0.0048
2771 Isocitrate dehydrogenase [NADP] icd 0.0048
3486 Fumarate hydratase class II fumC 0.0048
2942 Sialidase nanH 0.0048
3546 Sialidase nedA 0.0048
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0046
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0045
332 Beta-lactamase blaZ 0.0045
2478 Beta-lactamase ampC 0.0045
2613 Beta-lactamase ampC 0.0045
2635 Beta-lactamase ampC 0.0045
2700 Beta-lactamase penP 0.0045
5445 Beta-lactamase blaB 0.0045
6019 Beta-lactamase SHV-7 0.0045
6701 Beta-lactamase cphA 0.0045
1123 Eosinophil cationic protein RNASE3 0.0045
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0044
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0044
2452 Tryptophanyl-tRNA synthetase trpS 0.0044
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0042
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0042
5579 Carboxypeptidase B CPB1 0.0042
411 Glycine N-methyltransferase GNMT 0.0041
3384 Macrophage migration inhibitory factor MIF 0.0041
128 Adenine phosphoribosyltransferase APRT 0.0039
5304 UPF0166 protein TM_0021 TM_0021 0.0038
5293 Shikimate kinase 2 aroL 0.0038
5287 Signaling protein Not Available 0.0038
5288 Shikimate kinase aroK 0.0038
3199 Phosphopantetheine adenylyltransferase coaD 0.0038
3543 Phosphopantetheine adenylyltransferase coaD 0.0038
3567 Phosphopantetheine adenylyltransferase coaD 0.0038
5289 Phosphopantetheine adenylyltransferase coaD 0.0038
5292 Putative partitioning protein TT_C1605 0.0038
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0038
2874 Nitrogenase iron protein 1 nifH1 0.0038
4346 Polynucleotide kinase pseT 0.0038
5281 Plasmid segregation protein parM parM 0.0038
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0038
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0038
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0038
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0038
5266 Activator of hgdC 0.0038
5291 Glycogen synthase 1 glgA1 0.0038
5264 DNA replication protein REP 0.0038
5283 D-alanine--D-alanine ligase B ddlB 0.0038
5315 Chaperone protein htpG htpG 0.0038
5299 D-alanine--D-alanine ligase ddl 0.0038
6598 D-alanine--D-alanine ligase ddl 0.0038
5284 Large T antigen Not Available 0.0038
5276 Chromosomal replication initiator protein dnaA dnaA 0.0038
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0038
5259 Transcriptional regulator ntrC1 0.0038
6699 Transcriptional regulator Cgl2612 0.0038
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0038
5277 Preprotein translocase subunit secA secA 0.0038
5308 Preprotein translocase secA 1 subunit secA1 0.0038
5285 Kinesin heavy chain KIF5B 0.0038
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0038
5261 Phosphoribosylformylglycinamidine synthase purL 0.0038
2270 Dephospho-CoA kinase coaE 0.0033
2284 Adenylate kinase adk 0.0033
2296 Adenylate kinase adk 0.0033
2311 Adenylate kinase adk 0.0033
2312 Adenylate kinase Not Available 0.0033
4837 Cag-alfa cag-alfa 0.0033
3470 Hypothetical protein MG245 homolog MPN_348 0.0033
3426 Glutamine synthetase glnA 0.0033
3987 Glutamine synthetase GLUL 0.0033
4774 NTPase P4 Not Available 0.0033
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0033
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0033
4106 Guanylate kinase GUK1 0.0033
4516 Guanylate kinase gmk 0.0033
5646 Galactokinase GALK1 0.0033
5265 FtsH ftsH 0.0033
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0033
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0033
413 Amidophosphoribosyltransferase PPAT 0.0033
2515 Amidophosphoribosyltransferase purF 0.0033
3714 Amidophosphoribosyltransferase purF 0.0033
5302 TrwB trwB 0.0033
3175 Glutamate--cysteine ligase gshA 0.0033
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0033
4839 DNA polymerase III subunit tau dnaX 0.0033
6277 Heat shock cognate 71 kDa protein HSPA8 0.0033
5189 Trimethylamine dehydrogenase tmd 0.0033
4838 PMS1 protein homolog 2 PMS2 0.0033
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0032
822 Aldose reductase AKR1B1 0.0032
2683 Mono-ADP-ribosyltransferase C3 C3 0.0031
2390 Nonsecretory ribonuclease RNASE2 0.0031
2922 Glycerol kinase glpK 0.0031
5271 Focal adhesion kinase 1 PTK2 0.0031
5312 Kinesin-like protein KIF1A KIF1A 0.0031
340 Apoptotic protease-activating factor 1 APAF1 0.003
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.003
3669 Ribokinase rbsK 0.0029
2371 Pantothenate kinase coaA 0.0029
2892 Acetylglutamate kinase argB 0.0029
3550 Acetylglutamate kinase argB 0.0029
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0029
825 Arsenical pump-driving ATPase ASNA1 0.0029
3435 Arsenical pump-driving ATPase arsA 0.0029
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0029
2615 Chemotaxis protein cheA cheA 0.0029
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0029
1881 Hexokinase-1 HK1 0.0029
2282 Protein recA recA 0.0029
2315 Protein recA recA 0.0029
2332 Protein recA recA 0.0029
5263 Protein recA recA 0.0029
408 Riboflavin kinase RFK 0.0028
5300 Antigen peptide transporter 1 TAP1 0.0028
2727 S-adenosylmethionine synthetase metK 0.0028
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0028
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0027
2334 Dethiobiotin synthetase bioD 0.0027
6555 Dethiobiotin synthetase bioD 0.0027
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0027
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0027
788 Creatine kinase M-type CKM 0.0027
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0026
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0026
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0026
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0025
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0025
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0025
6395 Myosin-14 MYH14 0.0025
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0025
2251 Thymidylate kinase tmk 0.0024
2254 Thymidylate kinase DTYMK 0.0024
3522 Thymidylate kinase tmk 0.0024
2091 Endoplasmin HSP90B1 0.0024
48 Pyridoxal kinase PDXK 0.0024
1422 Serine/threonine-protein kinase 6 AURKA 0.0024
3379 Kinesin-like protein KIF11 KIF11 0.0023
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0023
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0023
3822 Actin, alpha skeletal muscle ACTA1 0.0023
207 Glutathione synthetase GSS 0.0022
5269 Glutathione synthetase gshB 0.0022
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0022
509 Thymidine kinase TK 0.0021
570 Thymidine kinase TK 0.0021
2559 Thymidine kinase TK 0.0021
3430 Thymidine kinase tdk 0.0021
3518 Thymidine kinase TK 0.0021
5301 Thymidine kinase tdk 0.0021
5771 Thymidine kinase ORF36 0.0021
7009 Thymidine kinase ORF36 0.0021
504 Mast/stem cell growth factor receptor KIT 0.0021
5294 Nucleoside diphosphate kinase A NME1 0.0021
1721 Glycogen synthase kinase-3 beta GSK3B 0.0021
4773 Deoxycytidine kinase DCK 0.0019
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0019
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0019
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0018
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