DT-Web

DB01862 - 1-(Isopropylthio)-Beta-Galactopyranside


Identification
Name 1-(Isopropylthio)-Beta-Galactopyranside
Accession Number DB01862 (EXPT01924)
Type small molecule
Description A non-metabolizable galactose analog that induces expression of the LAC operon. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 238.301
Groups experimental
Monoisotopic Weight 238.087494376
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Beta-galactosidase
Name Beta-galactosidase
Gene Name lacZ
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0257
Galactoside O-acetyltransferase
Name Galactoside O-acetyltransferase
Gene Name lacA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0009
Lactose operon repressor
Name Lactose operon repressor
Gene Name lacI
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.6111

Predictions


Id Partner name Gene Name Score
4669 Endo-1,4-beta-xylanase A xynA 0.0272
4715 Endo-1,4-beta-xylanase A xlnA 0.0272
5560 Endo-1,4-beta-xylanase A xynA 0.0272
4335 Trans-sialidase Not Available 0.0272
5481 Trans-sialidase TCTS-154 0.0272
3547 Enterotoxin type B entB 0.0251
4819 Hydrolase Not Available 0.0251
5249 Hydrolase Not Available 0.0251
5436 Hydrolase Not Available 0.0251
2942 Sialidase nanH 0.0237
3546 Sialidase nedA 0.0237
3382 Glycolipid transfer protein GLTP 0.0218
2570 Tetanus toxin tetX 0.0218
4579 Serine acetyltransferase cysE 0.0173
6807 Serine acetyltransferase cysE 0.0173
4576 Aac(6')-Ii protein aac(6')-Ii 0.0173
4577 4'-phosphopantetheinyl transferase sfp sfp 0.0173
4567 Putative acyl-CoA thioester hydrolase HI0827 HI_0827 0.0173
4564 YvbK protein yvbK 0.0173
4566 Acyl-CoA hydrolase BC_2038 0.0173
4572 Acyl-CoA hydrolase BH0798 0.0173
2528 Fatty acid metabolism regulator protein fadR 0.0173
6740 Fatty acid metabolism regulator protein fadR 0.0173
4037 Hypothetical protein GPX1 0.0173
4297 Hypothetical protein SP_1951 0.0173
4521 Hypothetical protein BC_2969 0.0173
4540 Hypothetical protein TM_1070 0.0173
4555 Hypothetical protein MT1739 0.0173
4569 Hypothetical protein mshD 0.0173
4578 Hypothetical protein PA3270 0.0173
4747 Hypothetical protein PA3967 0.0173
5177 Hypothetical protein TM_0096 0.0173
5194 Hypothetical protein PA1204 0.0173
5240 Hypothetical protein Rv2991 0.0173
5370 Hypothetical protein TM_1158 0.0173
5710 Hypothetical protein Tb927.5.1360 0.0173
5694 Transcription antiterminator licT licT 0.0167
5691 DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC rmlC 0.0167
3361 Serpin B5 SERPINB5 0.0167
3317 Holo-[acyl-carrier-protein] synthase acpS 0.015
4381 Holo-[acyl-carrier-protein] synthase acpS 0.015
4565 Aminoglycoside 6'-N-acetyltransferase aac(6')-Iy 0.015
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.015
3560 Gentamicin 3'-acetyltransferase aacC1 0.015
4563 Acetyl transferase rimL 0.015
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.015
4574 PROBABLE NAPHTHOATE SYNTHASE MENB menB 0.015
3489 Acetyl-coenzyme A synthetase acs 0.015
3729 Citrate synthase gltA 0.015
4575 Citrate synthase cit 0.015
4580 Citrate synthase gltA 0.015
3024 Crotonobetainyl-CoA:carnitine CoA-transferase caiB 0.015
2396 Formyl-coenzyme A transferase frc 0.015
3457 Formyl-coenzyme A transferase frc 0.015
2285 Streptogramin A acetyltransferase vatD 0.0139
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0139
3199 Phosphopantetheine adenylyltransferase coaD 0.0139
3543 Phosphopantetheine adenylyltransferase coaD 0.0139
3567 Phosphopantetheine adenylyltransferase coaD 0.0139
5289 Phosphopantetheine adenylyltransferase coaD 0.0139
2377 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Not Available 0.0138
4573 Histone acetyltransferase PCAF KAT2B 0.0138
2248 Malate synthase G glcB 0.0138
3190 Malate synthase G glcB 0.0138
3178 Formate acetyltransferase 1 pflB 0.0138
56 Delta-aminolevulinic acid dehydratase ALAD 0.0134
2356 Delta-aminolevulinic acid dehydratase hemB 0.0134
3613 Delta-aminolevulinic acid dehydratase hemB 0.0134
3674 Delta-aminolevulinic acid dehydratase hemB 0.0134
4404 FcbC1 protein fcbC 0.0131
2371 Pantothenate kinase coaA 0.0131
2286 Isocitrate dehydrogenase [NADP] icd 0.0126
2302 Isocitrate dehydrogenase [NADP] icd 0.0126
2771 Isocitrate dehydrogenase [NADP] icd 0.0126
2376 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase dapD 0.0125
4534 Cytohesin-2 CYTH2 0.0121
551 Carnitine O-acetyltransferase CRAT 0.012
3668 Maltose-binding periplasmic protein precursor malE 0.0116
2596 Acetyl-CoA acetyltransferase phbA 0.0114
615 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0113
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0113
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0113
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0113
4388 Aminoglycoside 2'-N-acetyltransferase aac 0.0109
315 Arginase-1 ARG1 0.0098
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0089
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0089
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0081
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0081
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0078
24 Thymidylate synthase TMP1 0.0073
359 Thymidylate synthase TYMS 0.0073
2626 Thymidylate synthase thyA 0.0073
2729 Thymidylate synthase thyA 0.0073
5352 Thymidylate synthase THYA 0.0073
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.007
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