| Name |
Tyrosyl-tRNA synthetase |
| Synonyms |
762 |
| Gene name |
YARS |
| General function |
Translation, ribosomal structure and biogenesis |
| Specific function |
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction:tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) |
| Gene sequence |
+ ...
ATGACTTATGTCAAAAAATATCATCCTACCACTAAATATTATGGTATTATTCATGGTGAAAAGTATGAATTACAAGACGTTTTATTTTACAGTTTTAATTACTCTAATAGAGAAGAAGTATGTCCAATTAGTGGTACTGCACATAAATCCAACGGATTTTATGTAATTGAAACCAGTAAAGGATACTTTATGAAATGCCATTCTGATAAATGTAAGAATAAAAAAGCCAAATATCTAGGTCCAGCTGATGCGACAGATATGTTTGTTAAATGTGCCAATCAAATTGATCAACAATACCTGATTATGAAAGGAGGAATTGCCGATGCTCCTAAAGAACCAGTTAAAGATATCATTATCAATTGGTTATCCAATGATAAAATTAAAACGTTGGCTGTTCGATCTCCAATGGGAACTGGAAAGACAACCATGATCAAAAAAATTCTTGATCATTATGACAATATCAAAAAAATATTATGGATATCTCATAGACAAACTTTATCCAAACAAATTTACGGATCTTTCAAAAATCACGGATTTGTTAATTACATGGATCAAAAAGGTAATCTGTTCGAACATGATAGACTTATTATTCAGATTGATAGTTTAAAAAGGATTTTTAAATACGACAAAGATTATAATACTGTATTTAAACAGTATGATTTGGTTATTATTGATGAGATCGAAGGGAACATGAATCATTTTATGAGTCCATATTTGAGAAAAGATTCTGATTTTTCTGTCAGACAAACTTTTCAGAAAATGTTGAATTGTATTGATACTGCTAAGAAACTACTAGTATTAGATGCCGATTTAGGAATGAGAAGTAAATTGTTTATTGATAATTTCGGTAAATCTATTGTCGTCAATAATAATTATAAACCTATCCAGAAGATTTTTGAGATTACTAATGATCTCTCTAGTTTTCAAGAAATTCTTCTAGCCGATATTAAAGATGGTAAAAATGTTTGTGTTGTTTCTATGTCAGCATCTTACTTGGATAAACTTGAACCTAAATTTGCCGGATTAAAGTATGTTATCCATACAAGTAAATCTGATGACAAACTCAAGAACGAACTTGAGAATGTAAATTATTTCTGGAAGAAATTTCAGATATGTTGTTTTAGTCCGACAATTGAATGTGGTGTTGATTTCAATGAGAAGCATTTTGATAAGATTTATTGTTATCTAAAAAATGGTTCCAAAACATGTTCACAAAGAAGTTTGTTGCAAATGGTTGGTAGGATTAGACAATTAGGTAATAATAAAATTCTCTGTTACTATTCAGGTCCTACTAATATTGATGCTGATATTTACACTTATGATGATATTCTTGGATATTTTAGACATTATGAAAAAATAAATGGTCGAAAAGTATTAGAAAATGTCGAATACAAAAAATTTATAGCCAATGGTGAAGTTACACTGAAAAGAGTTAGTGCTAATATTTCTCTATTTGATCATATTCACATTTATAATGAAGTCGAAGAATCCAATAAAAATCACTCGATGTTCATAACGGTGTTGTTTAAATTAATCCAAAGAGCCGGTCATTCAATGATTTTTAATACTGTTGAAGAACCTGAAGAAGTTGAACCTGATAATAATGTCATAAGTCATGCAGAAATTTTATCTATGATTAATGAAACAAAATACAAAATTTCAGATCTTATGAAAAAACAATCTAAAAATCAATTGTCACGTACCGAAAAATTGGTCCTAGAAAAATACTTTTTTATGAAAAATTTTGGTGTCAAAGATTCTTCTAATAAAGATGAATTCGTTAAATTTCACAAAAAATATGCCAATAAAGAAATCACATTCAAACATTTTAAGAGATTTTTTGGTTATGATAATCCTAATAATTCGATAGACGAATTAAAACATCTAGATATATTTGTTTCTAATAAGAAACCACCAAACAATAATAATAATAATTTCTTGGACGAACACAATGATAGTAAGGATGCTGTCAGAGATAAAATTATCGTTAATTTCCTTAATCTAATTCTAGATGTGAAAAAGAACGGATATGGACCAGATGATTTAGGCTACACATTAACTCAAGATGAACATAATACTGCTGTTTTAACTGTTGCTGAACAGTCTATGTACTTTGCAAACGAAGATAAATACAGACCTTTATTCAATAAAAATAAAGGTAAATTCAAAGAAATAAATGAATACAATTTCAAACATTACTTCAAAACTGTAAAGGCTATTCTTCAATCTTATGGAATAGATTACTATAGAGGTAATAGAAAAAGAGTCAATAGTAGAAGAGAATTTGAATATTCTTTATCTGTCGATAAACAGATAAGGGATATTGTCGATTTTAAGTTCGGATTATCTGATACTGTTGATGAATTTCCTAATTTGTTCCATAAATAG
|
| Protein sequence |
+ ...
MENTDHTNNEHRLTQLLSIAEECETLDRLKQLVDSGRIFTAYNGFEPSGRIHIAQALITVMNTNNIIECGGQMIIYIADWFAKMNLKMNGDINKIRELGRYFIEVFKACGINLDGTRFIWASEFIASNPSYIERMLDIAEFSTISRVKRCCQIMGRNESDCLKASQIFYPCMQAADVFELVPEGIDICQLGIDQRKVNMLAIEYANDRGLKIPISLSHHMLMSLSGPKKKMSKSDPQGAIFMDDTEQEVSEKISRAYCTDETFDNPIFEYIKYLLLRWFGTLNLCGKIYTDIESIQEDFSSMNKRELKTDVANYINTIIDLVREHFKKPELSELLSNVKSYQQPSK
|
| GO Classification |
| function |
| ligase activity |
| ligase activity, forming phosphoric ester bonds |
| RNA ligase activity |
| binding |
| tRNA ligase activity |
| nucleotide binding |
| catalytic activity |
| purine nucleotide binding |
| adenyl nucleotide binding |
| ATP binding |
| process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
| physiological process |
| RNA metabolism |
| tRNA metabolism |
| tRNA aminoacylation |
| metabolism |
| tRNA aminoacylation for protein translation |
| cellular metabolism |
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