| Name |
1-phosphatidylinositol phosphodiesterase |
| Synonyms |
5597 |
| Gene name |
plcA |
| General function |
Involved in phospholipase C activity |
| Specific function |
Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Important factor in pathogenesis, PI-PLC activity is present only in virulent listeria species. It may participate in the lysis of the phagolysosomal membrane |
| Gene sequence |
+ ...
TTGTATAAGAATTATTTGCAACGCACATTAGTTTTATTACTCTGTTTTATTTTATACTTTTTTACTTTCCCATTAGGCGGAAAAGCATATTCGCTTAATAACTGGAATAAGCCAATAAAGAACTCTGTAACTACAAAACAATGGATGTCCGCTCTACCTGACACAACAAACCTAGCAGCGCTCTCTATACCAGGTACACATGATACGATGAGCTATAACGGAGACATAACATGGACATTAACCAAACCACTAGCTCAAACACAAACGATGTCATTGTACCAACAACTAGAAGCAGGAATACGGTACATCGATATTAGAGCAAAAGACAATCTCAACATTTACCATGGGCCAATTTTTTTAAATGCATCACTTTCAGGTGTATTAGAAACGATTACTCAATTTTTAAAGAAAAATCCAAAAGAAACCATTATTATGCGTTTAAAAGACGAGCAAAACAGCAACGATAGTTTTGATTATCGGATCCAACCACTAATCAACATTTATAAAGATTATTTTTACACTACTCCCAGAACTGACACGAGCAATAAAATCCCTACATTAAAAGATGTCCGCGGAAAAATATTATTACTTTCAGAGAACCACACAAAAAAGCCATTAGTCATTAACTCACGCAAATTCGGCATGCAGTTCGGCGCACCTAACCAAGTAATTCAAGATGACTACAATGGTCCGAGTGTGAAAACAAAATTCAAAGAGATTGTCCAGACTGCTTATCAAGCTTCCAAAGCGGACAATAAACTTTTTCTTAACCATATTAGCGCCACTTCATTAACATTCACACCTCGTCAGTATGCTGCAGCATTAAACAACAAAGTAGAGCAATTCGTACTCAACTTAACATCGGAAAAAGTTCGAGGATTAGGCATACTAATCATGGACTTCCCCGAAAAACAAACAATTAAAAACATCATAAAAAACAATAAATTCAACTAA
|
| Protein sequence |
+ ...
MYKNYLQRTLVLLLCFILYFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
|
| GO Classification |
| function |
| phospholipase activity |
| phospholipase C activity |
| catalytic activity |
| hydrolase activity |
| hydrolase activity, acting on ester bonds |
| carboxylic ester hydrolase activity |
| lipase activity |
| process |
| cellular process |
| cell communication |
| signal transduction |
| intracellular signaling cascade |
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