| Name |
Stromal cell-derived factor 1 |
| Synonyms |
3740 |
| Gene name |
CXCL12 |
| General function |
Involved in cytokine activity |
| Specific function |
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites |
| Gene sequence |
+ ...
ATGAACGCCAAGGTCGTGGTCGTGCTGGTCCTCGTGCTGACCGCGCTCTGCCTCAGCGACGGGAAGCCCGTCAGCCTGAGCTACAGATGCCCATGCCGATTCTTCGAAAGCCATGTTGCCAGAGCCAACGTCAAGCATCTCAAAATTCTCAACACTCCAAACTGTGCCCTTCAGATTGTAGCCCGGCTGAAGAACAACAACAGACAAGTGTGCATTGACCCGAAGCTAAAGTGGATTCAGGAGTACCTGGAGAAAGCTTTAAACAAGAGGTTCAAGATGTGA
|
| Protein sequence |
+ ...
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
|
| GO Classification |
| component |
| extracellular region |
| function |
| chemokine activity |
| signal transducer activity |
| receptor binding |
| cytokine activity |
| process |
| response to stimulus |
| response to biotic stimulus |
| defense response |
| immune response |
|
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