DT-Web

DB07315 - 5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide


Identification
Name 5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide
Accession Number DB07315
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 330.766
Groups experimental
Monoisotopic Weight 330.077120063
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glycogen phosphorylase, liver form
Name Glycogen phosphorylase, liver form
Gene Name PYGL
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2165

Predictions


Id Partner name Gene Name Score
1152 Glycogen phosphorylase, muscle form PYGM 0.0599
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0127
2514 Phosphocarrier protein HPr ptsH 0.0116
5689 Phosphocarrier protein HPr ptsH 0.0116
3602 Anti-sigma F factor antagonist spoIIAA 0.0116
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0115
1130 Lithostathine 1 alpha REG1A 0.01
4542 Glutaminase 1 glsA1 0.01
4544 Glutaminase 1 glsA1 0.01
4318 Siroheme synthase cysG 0.0095
2530 Protein kinase C theta type PRKCQ 0.0092
3119 Fimbrial protein pilE1 0.0092
3453 Alkaline phosphatase phoA 0.0087
851 5'-AMP-activated protein kinase subunit beta-2 PRKAB2 0.0086
388 AMP deaminase 1 AMPD1 0.0086
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0084
2503 Phosphomannomutase/phosphoglucomutase algC 0.0084
5150 Endo-1,4-beta-xylanase Y xynY 0.0083
4198 Fructose-1,6-bisphosphatase 1 FBP1 0.0076
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0074
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0074
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0074
297 Adenylate cyclase type 1 ADCY1 0.0074
1291 cAMP response element-binding protein CREB1 0.0073
128 Adenine phosphoribosyltransferase APRT 0.0071
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.007
6021 Adenosine kinase ADK 0.0068
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0068
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0067
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0067
2207 Rhodopsin RHO 0.0065
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0061
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0054
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0053
3689 Endoglucanase A celA 0.0025
5563 Galectin-2 LGALS2 0.0025
5411 Slt-IIvB stxB2e 0.0025
5046 Ecotin eco 0.0025
5554 D-galactose-binding periplasmic protein mglB 0.0025
3741 D-galactose-binding periplasmic protein precursor mglB 0.0025
3009 Beta-glucanase Not Available 0.0025
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0025
5562 Hexokinase Not Available 0.0025
5568 Endoglucanase C307 celC307 0.0025
3744 Endoglucanase SS precursor celS 0.0025
3793 Aspartate ammonia-lyase aspA 0.0025
4668 Laminarinase TM_0024 0.0025
5569 Endo-1,4-beta glucanase EngF engF 0.0025
5553 Endoglucanase E1 Acel_0614 0.0025
5570 Endoglucanase E-4 celD 0.0025
5559 Neopullulanase nplT 0.0025
4670 Cellulase B celB 0.0025
1875 Pulmonary surfactant-associated protein D SFTPD 0.0025
4667 BH0236 protein BH0236 0.0025
4671 Endoglucanase C cenC 0.0025
3875 Glycogen phosphorylase, brain form PYGB 0.0023
3882 Brain glycogen phosphorylase variant Not Available 0.0023
1184 Interferon beta IFNB1 0.0022
4509 Acetoin(diacetyl) reductase budC 0.0022
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0022
5176 YtnJ moxC 0.0022
5498 Maltoporin lamB 0.0022
5561 Maltoporin lamB 0.0022
1503 Galectin-7 LGALS7 0.0022
5247 Endo-1,4-beta-xylanase Not Available 0.0022
5248 Endo-1,4-beta-xylanase xlnA 0.0022
5250 Endo-1,4-beta-xylanase xyl 0.0022
4669 Endo-1,4-beta-xylanase A xynA 0.0022
4715 Endo-1,4-beta-xylanase A xlnA 0.0022
5560 Endo-1,4-beta-xylanase A xynA 0.0022
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0022
5416 Coat protein VP1 Not Available 0.0022
4622 Amylase Not Available 0.0022
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0022
2705 Dimethyl sulfoxide reductase dmsA 0.0022
3887 Phosphorylase PYGB 0.0021
203 Pyridoxine-5'-phosphate oxidase PNPO 0.002
3091 Maltodextrin phosphorylase malP 0.002
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.002
3911 Uncharacterized protein C20orf38 SPTLC3 0.002
3883 Ornithine aminotransferase variant Not Available 0.002
3906 Serine dehydratase-like SDSL 0.002
3891 Putative L-Dopa decarboxylase DDC 0.002
3881 Selenocysteine lyase variant Not Available 0.002
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.002
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.002
306 Pyridoxal phosphate phosphatase PDXP 0.002
3893 DDC protein DDC 0.002
3908 P-selectin cytoplasmic tail-associated protein pcap 0.002
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.002
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.002
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.002
3878 GAD1 protein GAD1 0.002
664 Glutamate decarboxylase 2 GAD2 0.002
3890 Glutamate decarboxylase 2 GAD2 0.002
2531 Alpha-amylase amyE 0.002
2948 Alpha-amylase amy 0.002
3169 Alpha-amylase Not Available 0.002
3880 Serine hydroxymethyltransferase 1 Not Available 0.002
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.002
4819 Hydrolase Not Available 0.002
5249 Hydrolase Not Available 0.002
5436 Hydrolase Not Available 0.002
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.002
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.002
3905 Molybdenum cofactor sulfurase MOCOS 0.002
3886 Migration-inducing protein 4 ALAS1 0.002
2541 Neopullulanase 1 tvaI 0.002
3894 KIAA0251 protein PDXDC1 0.002
3547 Enterotoxin type B entB 0.002
2324 Botulinum neurotoxin type B botB 0.002
3747 Cellulase B precursor celB 0.002
2606 Neopullulanase 2 tvaII 0.002
4811 Amylosucrase ams 0.002
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.002
1881 Hexokinase-1 HK1 0.0019
2826 Glucose--fructose oxidoreductase gfo 0.0019
4666 Fucose-binding lectin PA-IIL lecB 0.0019
2372 Bifunctional tail protein 9 0.0019
4830 Aldose 1-epimerase galM 0.0019
3365 Beta-amylase spoII 0.0019
3225 Shiga toxin B-chain stxB 0.0019
472 Ornithine aminotransferase, mitochondrial OAT 0.0018
868 Cystathionine gamma-lyase CTH 0.0018
6614 Lactase-like protein LCTL 0.0018
1675 Glucokinase GCK 0.0018
4662 Glucokinase glk 0.0018
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0018
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0018
2508 Cyclomaltodextrin glucanotransferase cgt 0.0018
2523 Cyclomaltodextrin glucanotransferase cgt 0.0018
3207 Cyclomaltodextrin glucanotransferase amyA 0.0018
435 Kynureninase KYNU 0.0018
4654 Kynureninase kynU 0.0018
3030 Salivary alpha-amylase AMY1A 0.0018
4692 A/G-specific adenine glycosylase mutY 0.0018
449 Ornithine decarboxylase ODC1 0.0017
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0017
2802 Endoglucanase G celCCG 0.0017
2570 Tetanus toxin tetX 0.0017
3668 Maltose-binding periplasmic protein precursor malE 0.0017
3913 Glutamic acid decarboxylase GAD65 0.0017
184 L-serine dehydratase SDS 0.0017
431 Serine racemase SRR 0.0017
727 Serine palmitoyltransferase 2 SPTLC2 0.0017
491 Serine palmitoyltransferase 1 SPTLC1 0.0017
3 Histidine decarboxylase HDC 0.0017
4272 POSSIBLE CELLULASE CELA1 celA1 0.0017
534 Threonine synthase-like 1 THNSL1 0.0017
89 Cysteine sulfinic acid decarboxylase CSAD 0.0017
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0017
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0017
665 Phosphoserine aminotransferase PSAT1 0.0017
4652 Phosphoserine aminotransferase serC 0.0017
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0017
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0017
420 Glutamate decarboxylase 1 GAD1 0.0017
3900 Glutamate decarboxylase 1 GAD1 0.0017
499 Arginine decarboxylase ADC 0.0017
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0017
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0017
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0017
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0016
426 Aspartate aminotransferase, mitochondrial GOT2 0.0016
2430 Chondroitinase B cslB 0.0016
2440 Endoglucanase F celCCF 0.0016
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0016
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0016
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0016
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0016
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0016
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0016
349 Serine--pyruvate aminotransferase AGXT 0.0016
358 Cystathionine beta-synthase CBS 0.0016
3884 SHMT2 protein SHMT2 0.0016
3901 SHMT2 protein SHMT2 0.0016
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0016
3879 Serine hydroxymethyltransferase 2 Not Available 0.0016
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0016
169 Cysteine desulfurase, mitochondrial NFS1 0.0015
3877 Growth-inhibiting protein 18 GIG18 0.0015
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0015
2245 Xylose isomerase xylA 0.0015
2253 Xylose isomerase xylA 0.0015
2260 Xylose isomerase xylA 0.0015
2431 Xylose isomerase xylA 0.0015
2252 Endoglucanase 5A cel5A 0.0015
763 Tyrosine aminotransferase TAT 0.0015
5493 Tyrosine aminotransferase Not Available 0.0015
2723 Cholera enterotoxin subunit B ctxB 0.0015
735 Alanine aminotransferase 1 GPT 0.0014
3904 Alanine aminotransferase 2 GPT2 0.0014
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0014
2427 Ferrichrome-iron receptor fhuA 0.0014
4513 Pancreatic alpha-amylase AMY2A 0.0014
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0014
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0014
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0013
20 Prostaglandin G/H synthase 1 PTGS1 0.0007
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