DT-Web

DB07173 - 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE


Identification
Name 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
Accession Number DB07173
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 376.1504
Groups experimental
Monoisotopic Weight 376.003233722
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenosine kinase
Name Adenosine kinase
Gene Name ADK
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6657

Predictions


Id Partner name Gene Name Score
6171 Solute carrier family 28 member 3 SLC28A3 0.0582
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0434
311 RNA-directed RNA polymerase catalytic subunit PB1 0.0392
752 Large structural protein L 0.0391
390 Adenosine A3 receptor ADORA3 0.038
268 Adenosine A2b receptor ADORA2B 0.0356
508 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1 0.0303
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0268
1178 Adenosine A2a receptor ADORA2A 0.0266
16 Adenosine A1 receptor ADORA1 0.0261
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.026
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.026
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.026
297 Adenylate cyclase type 1 ADCY1 0.026
3957 Adenosine deaminase ADA 0.0247
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0229
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0218
851 5'-AMP-activated protein kinase subunit beta-2 PRKAB2 0.0203
388 AMP deaminase 1 AMPD1 0.0203
1291 cAMP response element-binding protein CREB1 0.0154
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0154
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.015
128 Adenine phosphoribosyltransferase APRT 0.0131
4198 Fructose-1,6-bisphosphatase 1 FBP1 0.0119
10 Glycogen phosphorylase, liver form PYGL 0.0108
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0099
825 Arsenical pump-driving ATPase ASNA1 0.0098
3435 Arsenical pump-driving ATPase arsA 0.0098
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0098
733 Activin receptor type 1B ACVR1B 0.0098
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0098
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0098
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0098
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0098
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0098
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0098
154 AFG3-like protein 2 AFG3L2 0.0098
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0098
395 ALK tyrosine kinase receptor Not Available 0.0098
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0095
340 Apoptotic protease-activating factor 1 APAF1 0.0094
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0088
292 Activin receptor type-1 ACVR1 0.0082
849 Activated CDC42 kinase 1 TNK2 0.0082
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0074
484 Tyrosine-protein kinase ABL2 ABL2 0.007
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0065
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0064
661 ADP/ATP translocase 1 SLC25A4 0.0061
740 Argininosuccinate synthase ASS1 0.0059
865 Argininosuccinate synthase ASS1 0.0059
2680 Argininosuccinate synthase argG 0.0059
3194 Argininosuccinate synthase argG 0.0059
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0055
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0052
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0046
776 Bile salt export pump ABCB11 0.0038
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0032
1588 Multidrug resistance protein 1 ABCB1 0.0025
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