DT-Web

DB07010 - N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE


Identification
Name N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE
Accession Number DB07010
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 376.839
Groups experimental
Monoisotopic Weight 376.109088893
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Mitogen-activated protein kinase 1
Name Mitogen-activated protein kinase 1
Gene Name MAPK1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0347
Mitogen-activated protein kinase 10
Name Mitogen-activated protein kinase 10
Gene Name MAPK10
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7344

Predictions


Id Partner name Gene Name Score
6653 cDNA FLJ42801 fis, clone BRCAN2001223, highly similar to Mitogen-activated protein kinase 10 (EC 2.7.11.24) MAPK10 0.103
1540 Mitogen-activated protein kinase 14 MAPK14 0.09
1372 Insulin receptor substrate 1 IRS1 0.065
6293 Dual specificity protein kinase TTK TTK 0.0441
36 Insulin receptor INSR 0.0421
1714 Mitogen-activated protein kinase 3 MAPK3 0.0352
6292 Mitogen-activated protein kinase 8 MAPK8 0.0348
6291 C-jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 0.0334
3959 Cell division protein kinase 4 CDK4 0.0284
1742 D-HSCDK2 CDK2deltaT 0.0274
1771 Cell division control protein 2 homolog CDK1 0.0274
3321 Cell division control protein 2 homolog CRK2 0.0274
2240 Cell division protein kinase 2 CDK2 0.0269
1058 Cell division protein kinase 5 CDK5 0.0266
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0256
4751 Mitogen-activated protein kinase 12 MAPK12 0.0222
4750 Protein S100-A11 S100A11 0.0216
3482 Cell division protein kinase 7 CDK7 0.0189
3005 Threonine-phosphate decarboxylase cobD 0.0188
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0181
2530 Protein kinase C theta type PRKCQ 0.0174
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0173
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0173
1422 Serine/threonine-protein kinase 6 AURKA 0.0135
1517 Beta-3 adrenergic receptor ADRB3 0.0127
2207 Rhodopsin RHO 0.0122
6024 Cytochrome P450 1A1 CYP1A1 0.0115
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0109
1569 G1/S-specific cyclin-D1 CCND1 0.0106
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0102
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0102
1629 Transcription factor AP-1 JUN 0.0086
193 Beta-1 adrenergic receptor ADRB1 0.0086
766 Beta-2 adrenergic receptor ADRB2 0.0083
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0082
1898 Cytochrome P450 1B1 CYP1B1 0.0056
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0048
5643 General secretion pathway protein E epsE 0.0038
5641 Rod shape-determining protein MreB TM_0588 0.0038
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0038
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
3794 Osmolarity sensor protein envZ envZ 0.0038
5644 Sensor protein phoQ phoQ 0.0038
5642 Chaperone clpB clpB 0.0038
5645 DNA topoisomerase 4 subunit B parE 0.0038
6227 DNA topoisomerase 4 subunit B parE 0.0038
5649 Potassium-transporting ATPase B chain kdpB 0.0038
1588 Multidrug resistance protein 1 ABCB1 0.0038
5646 Galactokinase GALK1 0.0033
740 Argininosuccinate synthase ASS1 0.0033
865 Argininosuccinate synthase ASS1 0.0033
2680 Argininosuccinate synthase argG 0.0033
3194 Argininosuccinate synthase argG 0.0033
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0033
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0033
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0033
2282 Protein recA recA 0.0033
2315 Protein recA recA 0.0033
2332 Protein recA recA 0.0033
5263 Protein recA recA 0.0033
2397 Dihydroxyacetone kinase dhaK 0.0033
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0033
5302 TrwB trwB 0.0033
2852 DNA mismatch repair protein mutL mutL 0.0033
5265 FtsH ftsH 0.0033
4512 Cytochrome P450 3A4 CYP3A4 0.0033
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0031
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0031
3231 Death-associated protein kinase 1 DAPK1 0.0031
5312 Kinesin-like protein KIF1A KIF1A 0.0031
2892 Acetylglutamate kinase argB 0.0029
3550 Acetylglutamate kinase argB 0.0029
2371 Pantothenate kinase coaA 0.0029
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0029
825 Arsenical pump-driving ATPase ASNA1 0.0029
3435 Arsenical pump-driving ATPase arsA 0.0029
2615 Chemotaxis protein cheA cheA 0.0029
1881 Hexokinase-1 HK1 0.0029
2727 S-adenosylmethionine synthetase metK 0.0028
887 DNA gyrase subunit B gyrB 0.0027
4150 DNA gyrase subunit B gyrB 0.0027
6225 DNA gyrase subunit B gyrB 0.0027
936 Ephrin type-A receptor 2 EPHA2 0.0027
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0027
958 Insulin-like growth factor 1 receptor IGF1R 0.0025
2251 Thymidylate kinase tmk 0.0024
2254 Thymidylate kinase DTYMK 0.0024
3522 Thymidylate kinase tmk 0.0024
3822 Actin, alpha skeletal muscle ACTA1 0.0023
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0022
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0022
4192 DNA topoisomerase 2-beta TOP2B 0.0021
207 Glutathione synthetase GSS 0.0021
5269 Glutathione synthetase gshB 0.0021
1721 Glycogen synthase kinase-3 beta GSK3B 0.0021
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0021
2236 Casein kinase II subunit alpha CSNK2A1 0.002
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