DT-Web

DB04493 - Fructose-6-Phosphate


Identification
Name Fructose-6-Phosphate
Accession Number DB04493 (EXPT01383)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 260.1358
Groups experimental
Monoisotopic Weight 260.029718526
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Fructose-1,6-bisphosphatase 1
Name Fructose-1,6-bisphosphatase 1
Gene Name FBP1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8667
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene Name PFKFB1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0725
6-phosphofructokinase
Name 6-phosphofructokinase
Gene Name pfkA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6488
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Gene Name PFKFB4
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5863
Glucose-6-phosphate isomerase
Name Glucose-6-phosphate isomerase
Gene Name GPI
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3105

Predictions


Id Partner name Gene Name Score
2314 Triosephosphate isomerase TPI 0.1716
3417 Triosephosphate isomerase tpiA 0.1716
3443 Triosephosphate isomerase tpiA 0.1716
6346 Triosephosphate isomerase TPI1 0.1716
2677 Glucose-6-phosphate isomerase B pgiB 0.1405
2803 Pyridoxine 5'-phosphate synthase pdxJ 0.1258
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.1002
2621 Thermoresistant gluconokinase gntK 0.0937
3134 Phospho-2-dehydro-3-deoxyheptonate aldolase aroF 0.0937
2904 Phosphatase yniC yniC 0.089
3676 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive aroG 0.0775
3192 Glucosamine-6-phosphate deaminase 1 nagB 0.0775
3467 Methylglyoxal synthase mgsA 0.0715
2310 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.071
2542 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.071
52 Pyruvate kinase isozymes R/L PKLR 0.0625
2897 ATP-dependent DNA helicase recQ recQ 0.0587
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0583
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0559
4837 Cag-alfa cag-alfa 0.0511
2878 Probable serine/threonine-protein kinase pknB pknB 0.0511
4839 DNA polymerase III subunit tau dnaX 0.0511
4838 PMS1 protein homolog 2 PMS2 0.0511
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.051
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.049
1881 Hexokinase-1 HK1 0.0433
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0402
1673 GTP cyclohydrolase I GCH1 0.0313
3302 GTP cyclohydrolase I folE 0.0313
3209 Ornithine decarboxylase, inducible odcI 0.0313
2393 Maltose-6'-phosphate glucosidase glvA 0.0312
2538 6-phospho-beta-glucosidase bglT bglT 0.0312
3335 Probable GTP-binding protein engB engB 0.0273
3354 Ras-related protein Rap-2a RAP2A 0.0273
3311 mRNA-capping enzyme A103R 0.0273
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0273
2647 RNA-directed RNA polymerase P2 0.0273
2439 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] otsA 0.0272
2503 Phosphomannomutase/phosphoglucomutase algC 0.026
1758 GTPase HRas HRAS 0.0227
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0213
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0213
3794 Osmolarity sensor protein envZ envZ 0.0213
5641 Rod shape-determining protein MreB TM_0588 0.0213
5644 Sensor protein phoQ phoQ 0.0213
6316 ADP-ribosylation factor 1 ARF1 0.0213
5643 General secretion pathway protein E epsE 0.0213
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0213
5645 DNA topoisomerase 4 subunit B parE 0.0213
6227 DNA topoisomerase 4 subunit B parE 0.0213
5649 Potassium-transporting ATPase B chain kdpB 0.0213
5642 Chaperone clpB clpB 0.0212
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0204
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.02
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0185
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0185
2282 Protein recA recA 0.0185
2315 Protein recA recA 0.0185
2332 Protein recA recA 0.0185
5263 Protein recA recA 0.0185
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0185
4751 Mitogen-activated protein kinase 12 MAPK12 0.0185
5646 Galactokinase GALK1 0.0185
740 Argininosuccinate synthase ASS1 0.0185
865 Argininosuccinate synthase ASS1 0.0185
2680 Argininosuccinate synthase argG 0.0185
3194 Argininosuccinate synthase argG 0.0185
5302 TrwB trwB 0.0185
2397 Dihydroxyacetone kinase dhaK 0.0185
2852 DNA mismatch repair protein mutL mutL 0.0185
5265 FtsH ftsH 0.0185
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.018
822 Aldose reductase AKR1B1 0.0178
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0171
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0171
3231 Death-associated protein kinase 1 DAPK1 0.0171
5312 Kinesin-like protein KIF1A KIF1A 0.0171
2297 Genome polyprotein Not Available 0.0163
2322 Genome polyprotein Not Available 0.0163
2694 Genome polyprotein Not Available 0.0163
2719 Genome polyprotein Not Available 0.0163
2860 Genome polyprotein Not Available 0.0163
2928 Genome polyprotein Not Available 0.0163
3160 Genome polyprotein Not Available 0.0163
3260 Genome polyprotein Not Available 0.0163
4783 Genome polyprotein Not Available 0.0163
5726 Genome polyprotein Not Available 0.0163
5779 Genome polyprotein Not Available 0.0163
5867 Genome polyprotein Not Available 0.0163
6253 Genome polyprotein Not Available 0.0163
6301 Genome polyprotein Not Available 0.0163
6380 Genome polyprotein Not Available 0.0163
6381 Genome polyprotein Not Available 0.0163
6437 Genome polyprotein Not Available 0.0163
6520 Genome polyprotein Not Available 0.0163
6521 Genome polyprotein Not Available 0.0163
6652 Genome polyprotein Not Available 0.0163
6734 Genome polyprotein Not Available 0.0163
6735 Genome polyprotein Not Available 0.0163
6736 Genome polyprotein Not Available 0.0163
6737 Genome polyprotein Not Available 0.0163
6738 Genome polyprotein Not Available 0.0163
6739 Genome polyprotein Not Available 0.0163
6744 Genome polyprotein Not Available 0.0163
6748 Genome polyprotein Not Available 0.0163
6894 Genome polyprotein Not Available 0.0163
6898 Genome polyprotein Not Available 0.0163
1152 Glycogen phosphorylase, muscle form PYGM 0.0163
2892 Acetylglutamate kinase argB 0.0161
3550 Acetylglutamate kinase argB 0.0161
2371 Pantothenate kinase coaA 0.0161
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0161
825 Arsenical pump-driving ATPase ASNA1 0.0161
3435 Arsenical pump-driving ATPase arsA 0.0161
2615 Chemotaxis protein cheA cheA 0.0161
2727 S-adenosylmethionine synthetase metK 0.0154
887 DNA gyrase subunit B gyrB 0.0149
4150 DNA gyrase subunit B gyrB 0.0149
6225 DNA gyrase subunit B gyrB 0.0149
936 Ephrin type-A receptor 2 EPHA2 0.0148
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0147
958 Insulin-like growth factor 1 receptor IGF1R 0.0137
2251 Thymidylate kinase tmk 0.0134
2254 Thymidylate kinase DTYMK 0.0134
3522 Thymidylate kinase tmk 0.0134
3822 Actin, alpha skeletal muscle ACTA1 0.0125
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0123
851 5'-AMP-activated protein kinase subunit beta-2 PRKAB2 0.0121
1836 Mitogen-activated protein kinase 10 MAPK10 0.0121
388 AMP deaminase 1 AMPD1 0.0121
4192 DNA topoisomerase 2-beta TOP2B 0.0119
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0119
207 Glutathione synthetase GSS 0.0118
5269 Glutathione synthetase gshB 0.0118
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0117
1721 Glycogen synthase kinase-3 beta GSK3B 0.0114
2236 Casein kinase II subunit alpha CSNK2A1 0.0113
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0103
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0103
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0103
297 Adenylate cyclase type 1 ADCY1 0.0103
1291 cAMP response element-binding protein CREB1 0.01
128 Adenine phosphoribosyltransferase APRT 0.0098
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.0097
10 Glycogen phosphorylase, liver form PYGL 0.0095
6021 Adenosine kinase ADK 0.0094
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0093
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0083
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0072
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