DT-Web

DB03557 - N-{1-[5-(1-Carbamoyl-2-Mercapto-Ethylcarbamoyl)-Pentylcarbamoyl]-2-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Ethyl}-3-{2-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Acetylamino}-Succinamic Acid


Identification
Name N-{1-[5-(1-Carbamoyl-2-Mercapto-Ethylcarbamoyl)-Pentylcarbamoyl]-2-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Ethyl}-3-{2-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Acetylamino}-Succinamic Acid
Accession Number DB03557 (EXPT02927)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 873.7
Groups experimental
Monoisotopic Weight 873.183292957
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Tyrosine-protein phosphatase non-receptor type 1
Name Tyrosine-protein phosphatase non-receptor type 1
Gene Name PTPN1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8574

Predictions


Id Partner name Gene Name Score
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0227
6057 V-type proton ATPase catalytic subunit A ATP6V1A 0.0193
136 Estrogen receptor ESR1 0.0125
3105 M-phase inducer phosphatase 2 CDC25B 0.0076
4340 Hypothetical conserved protein GK2698 0.0049
6484 Hypothetical conserved protein TT_C0834 0.0049
4341 Beta crystallin B1 CRYBB1 0.0049
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0049
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0049
1434 Protein DJ-1 PARK7 0.0049
4339 Sucrose phosphorylase sucP 0.0049
5366 Sugar-phosphate isomerase TM_1080 0.0046
5367 Peroxiredoxin prx 0.0046
5369 Golgi-associated plant pathogenesis-related protein 1 GLIPR2 0.0046
4037 Hypothetical protein GPX1 0.0046
4297 Hypothetical protein SP_1951 0.0046
4521 Hypothetical protein BC_2969 0.0046
4540 Hypothetical protein TM_1070 0.0046
4555 Hypothetical protein MT1739 0.0046
4569 Hypothetical protein mshD 0.0046
4578 Hypothetical protein PA3270 0.0046
4747 Hypothetical protein PA3967 0.0046
5177 Hypothetical protein TM_0096 0.0046
5194 Hypothetical protein PA1204 0.0046
5240 Hypothetical protein Rv2991 0.0046
5370 Hypothetical protein TM_1158 0.0046
5710 Hypothetical protein Tb927.5.1360 0.0046
4699 Methylaspartate ammonia-lyase Not Available 0.0046
5365 Metallo beta-lactamase blaVIM-2 0.0046
2688 Peptide deformylase def 0.0043
2708 Peptide deformylase def 0.0043
3004 Peptide deformylase def 0.0043
4337 Peptide deformylase def 0.0043
4338 Peptide deformylase def 0.0043
5368 Peptide deformylase def 0.0043
5371 Peptide deformylase def 0.0043
6375 Peptide deformylase def 0.0043
6378 Peptide deformylase def 0.0043
6379 Peptide deformylase def 0.0043
6776 Peptide deformylase def 0.0043
6900 Peptide deformylase def 0.0043
3421 Hydroxyethylthiazole kinase thiM 0.0043
3596 Deoxynucleotide monophosphate kinase 1 0.004
3858 Cathepsin L CTSL1 0.004
4343 Alpha-glucosidase aglA 0.0039
2664 S-ribosylhomocysteine lyase luxS 0.0035
2725 S-ribosylhomocysteine lyase luxS 0.0035
2840 Beta-lactamase IMP-1 Not Available 0.0034
2385 Penicillin acylase Not Available 0.0032
3873 Prolyl endopeptidase PREP 0.0032
6928 Prolyl endopeptidase Not Available 0.0032
615 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.003
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.003
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.003
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.003
2240 Cell division protein kinase 2 CDK2 0.0018
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