DT-Web

DB03469 - Heme D


Identification
Name Heme D
Accession Number DB03469 (EXPT01189)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 712.484
Groups experimental
Monoisotopic Weight 712.146785397
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Nitrite reductase
Name Nitrite reductase
Gene Name nirS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8194
Nitrite reductase
Name Nitrite reductase
Gene Name nirS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8194

Predictions


Id Partner name Gene Name Score
3497 Ribonuclease PH rph 0.1124
5214 Phosphoprotein P/V 0.1123
3444 Cyanovirin-N Not Available 0.0903
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0851
5221 Cytochrome c3, 13 kDa Not Available 0.067
5220 Split-Soret cytochrome c Ddes_2150 0.067
3152 Cytochrome c'' cycA 0.067
3700 Cytochrome c-552 precursor nrfA 0.0669
4948 Cytochrome c-553 Not Available 0.0626
4923 Cytochrome c3 DvMF_2499 0.0626
4945 Cytochrome c3 Not Available 0.0626
4949 Cytochrome c3 DVU_3171 0.0626
4968 Cytochrome c3 cytc3 0.0626
4997 Cytochrome c3 SO_2727 0.0626
5219 Cytochrome c3 cyd 0.0626
4902 Nine-heme cytochrome c Ddes_2038 0.0626
3189 High-molecular-weight cytochrome c hmcA 0.0625
4386 Hemoglobin-like protein HbN glbN 0.0577
3221 Cytochrome c4 cc4 0.0545
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0507
1507 Cytochrome c CYCS 0.0464
4757 Cytochrome P450 2C9 CYP2C9 0.0163
4925 Cytochrome c-type protein SHP shp 0.0049
4943 Cytochrome c6 petJ 0.0049
4954 Soluble cytochrome b558 Not Available 0.0049
4942 Diheme cytochrome c napB napB 0.0049
4934 Cytochrome c-551 nirM 0.0049
5218 Cytochrome c-551 nirM 0.0049
4936 Cytochrome c2 iso-2 Not Available 0.0049
4981 Iron-starvation protein PigA pigA 0.0049
4915 Cytochrome c-550 psbV 0.0049
4959 Cytochrome c-550 psbV 0.0049
5216 Cytochrome c-550 psbV 0.0049
4905 Cytochrome c2 Not Available 0.0049
4939 Cytochrome c2 cycA 0.0049
4964 Cytochrome c2 cycA 0.0049
4979 Cytochrome c2 cycA 0.0049
6673 Cytochrome c2 cycA 0.0049
4975 Cytochrome c-556 RPA3973 0.0049
3116 Bacterioferritin bfr 0.0049
4906 Bacterioferritin bfr 0.0049
4965 Bacterioferritin bfr 0.0049
4961 Hemophore HasA hasA 0.0049
4910 Cytoglobin CYGB 0.0049
4984 Neuroglobin NGB 0.0049
4907 Cytochrome c-L moxG 0.0049
6865 Cytochrome c-L moxG 0.0049
4971 Nonaheme cytochrome c hmcA 0.0049
4989 Cytochrome c551 peroxidase ccp 0.0049
5222 Cytochrome c551 peroxidase ccpA 0.0049
4976 Apocytochrome f petA 0.0049
6407 Apocytochrome f petA 0.0049
4916 Cyanoglobin glbN 0.0049
4909 CooA protein cooA 0.0049
4994 Hemoglobin-like protein HbO glbO 0.0049
5000 HemO hemO 0.0049
4998 Hemoglobin-like protein yjbI yjbI 0.0049
4935 Cytochrome c-554 cycA1 0.0049
644 Heme oxygenase 2 HMOX2 0.0049
4982 Heme oxygenase 2 pbsA2 0.0049
4947 Bacterial hemoglobin vhb 0.0049
4764 Cytochrome P450 165C4 CYP165C4 0.0049
4960 Putative cytochrome P450-family protein SCO7417 0.0049
4937 Cytochrome oxidase subunit II rcoxA 0.0049
4904 Cytochrome c family protein GSU1996 0.0049
4999 Cytochrome P450 165B3 CYP165B3 0.0049
4972 P450cin cinA 0.0049
4931 Cytochrome P450 167A1 CYP167A1 0.0049
4926 Heme-based aerotactic transducer hemAT hemAT 0.0049
4922 Cytochrome c, putative SO_4144 0.0049
4952 Catalase/peroxidase katA 0.0049
3093 Catalase HPII katE 0.0049
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0049
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0049
4993 Hydroxylamine oxidoreductase hao1 0.0049
4903 Methyl-accepting chemotaxis protein Tar4 0.0049
4385 Cytochrome c' Not Available 0.0043
4967 Cytochrome c' cycA 0.0043
5038 Cytochrome c' Not Available 0.0043
5223 Cytochrome c' cycP 0.0043
4813 Heme oxygenase hmuO 0.0043
5769 Heme oxygenase Not Available 0.0043
4990 PpcA ppcA 0.0043
3375 Acidic cytochrome c3 Not Available 0.0043
4037 Hypothetical protein GPX1 0.0043
4297 Hypothetical protein SP_1951 0.0043
4521 Hypothetical protein BC_2969 0.0043
4540 Hypothetical protein TM_1070 0.0043
4555 Hypothetical protein MT1739 0.0043
4569 Hypothetical protein mshD 0.0043
4578 Hypothetical protein PA3270 0.0043
4747 Hypothetical protein PA3967 0.0043
5177 Hypothetical protein TM_0096 0.0043
5194 Hypothetical protein PA1204 0.0043
5240 Hypothetical protein Rv2991 0.0043
5370 Hypothetical protein TM_1158 0.0043
5710 Hypothetical protein Tb927.5.1360 0.0043
2119 Cytochrome b5 CYB5A 0.0043
2915 Sensor protein fixL fixL 0.0043
4944 Sensor protein fixL fixL 0.0043
4992 Cytochrome c peroxidase Not Available 0.0043
4289 Cytochrome P450 TT_P0059 0.0043
6262 Cytochrome P450 staP 0.0043
3570 Cytochrome P450 152A1 cypC 0.0043
4988 Sulfite oxidase, mitochondrial SUOX 0.0043
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0042
4920 Peroxidase/catalase katG 0.0042
3291 Cytochrome c-552 cycA 0.0039
4927 Cytochrome c-552 nrfA 0.0039
4938 Cytochrome c-552 cycA 0.0039
4953 Cytochrome c-552 nrfA 0.0039
5217 Cytochrome c-552 cycM 0.0039
3670 Soluble cytochrome b562 precursor cybC 0.0039
2617 Nitric oxide synthase oxygenase nos 0.0039
2701 Nitric oxide synthase oxygenase nos 0.0039
3411 Cytochrome P450 121 cyp121 0.0039
3102 Flavohemoprotein hmp 0.0039
4969 Flavohemoprotein hmp 0.0039
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0037
2230 Catalase CAT 0.0036
3249 Catalase katA 0.0036
3625 Catalase katA 0.0036
4539 Catalase katA 0.0036
4941 Catalase katB 0.0036
4608 Putative cytochrome P450 SCO1207 0.0035
4963 Putative cytochrome P450 SCO2884 0.0035
6254 Putative cytochrome P450 SCO6998 0.0035
605 Fumarate reductase flavoprotein subunit frdA 0.0034
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0034
3673 Fumarate reductase flavoprotein subunit fccA 0.0034
4912 Fumarate reductase flavoprotein subunit ifcA 0.0034
6549 Fumarate reductase flavoprotein subunit frdA 0.0034
2972 6-deoxyerythronolide B hydroxylase eryF 0.0034
260 Cytochrome P450 51 ERG11 0.0033
761 Cytochrome P450 51 ERG11 0.0033
3163 Cytochrome P450 51 cyp51 0.0033
518 Peroxidase/catalase T katG 0.0032
693 Hemoglobin subunit beta HBB 0.0031
6268 Hydroxyacid oxidase 1 HAO1 0.0031
810 Heme oxygenase 1 HMOX1 0.0029
3391 Heme oxygenase 1 pbsA1 0.0029
358 Cystathionine beta-synthase CBS 0.0027
2298 Cytochrome P450-cam camC 0.0027
76 Nitric-oxide synthase, brain NOS1 0.0025
7 Nitric oxide synthase, inducible NOS2 0.0022
291 Nitric-oxide synthase, endothelial NOS3 0.0022
275 Arachidonate 5-lipoxygenase ALOX5 0.0022
6106 Cytochrome P450 2C18 CYP2C18 0.0018
290 Prostaglandin G/H synthase 2 PTGS2 0.0016
20 Prostaglandin G/H synthase 1 PTGS1 0.0015
587 Serum albumin ALB 0.0014
6030 Cytochrome P450 2B6 CYP2B6 0.0014
4924 Cytochrome P450 2C8 CYP2C8 0.0013
4512 Cytochrome P450 3A4 CYP3A4 0.0011
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