| Name |
Ribonuclease PH |
| Synonyms |
5542 |
| Gene name |
rph |
| General function |
Translation, ribosomal structure and biogenesis |
| Specific function |
Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates |
| Gene sequence |
+ ...
TCATTCGGCCAGCGCGGCGCGCTGAGTTCGAACAAGCTCCTGCATGCCCTGCTGGGCCAGTTCGAGCATGGCGTTCAGCTCGGCGGGACGGAACGGCGCGCCTTCGGCGGTTCCCTGCACCTCGATGAACCGCCGGCAATCGGTCATCACTACGTTCAGGTCGGATTCCGCGGCGGAATCCTCCAGGTAGTCCAGGTCGAGGACCGGCACCCCCTGGTAGATGCCCACGGAAACGGCGGCGACTATTTGCTTCAGCGGATTGCCCTTGAGCGCGACACGCTTCTTCAGCACCGCCAGGGCGTCGATCAGCGACACGGTGGCGCCGGTGATTGAGGCGGTGCGGGTGCCGCCGTCGGTCTGGATCACGTCGCAGTCGATGTACAGGGTGTTCTCGCCGAGCTTGCTGAGGTCCAGCGCCGCTCGCAGGGAGCGGTCGATCAGGCGCTGGATCTCCAGGGTACGACCGCCCTGCTTGCCGCGGCTGGCCTCGCGCTGGTTACGCTCGCCCGTGGAGCGCCGCAGCATGCCGTACTCGGCGGTCAACCAACCCTGGCCCTGGCCCTTGAGGAAGCGCGGCACCCCGGACTCGGCGCTGACGGTGCAGATCACCTTGGTATCGCCGAACTCGACCAGCACCGAACCTTCTGCGTGCTTGGTGTAATGGCGGGTGATGCGGATCGGGCGCAGCTGGTCGGCGGCACGGCCACTGGGACGATTCAT
|
| Protein sequence |
+ ...
MNRPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLKGQGQGWLTAEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDLSKLGENTLYIDCDVIQADGGTRTASITGATVALIDALAVLKKRGALKGNPLKQMVAAVSVGIYQGVPVLDLDYLEDSAAETDLNVVMTDAGGFIEVQGTAEGAPFRPAELNAMLELAQQGMQELFELQRAALAE
|
| GO Classification |
| function |
| hydrolase activity, acting on ester bonds |
| tRNA binding |
| nuclease activity |
| binding |
| exonuclease activity |
| 3'-5' exonuclease activity |
| catalytic activity |
| ribonuclease activity |
| tRNA-specific ribonuclease activity |
| hydrolase activity |
| 3'-5'-exoribonuclease activity |
| nucleic acid binding |
| RNA binding |
| process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
| RNA metabolism |
| physiological process |
| RNA processing |
| metabolism |
| cellular metabolism |
| tRNA processing |
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