DT-Web

DB02458 - Glutathione S-(2,4 Dinitrobenzene)


Identification
Name Glutathione S-(2,4 Dinitrobenzene)
Accession Number DB02458 (DB04412, EXPT01572)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 473.415
Groups experimental
Monoisotopic Weight 473.085262543
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glutathione S-transferase Mu 1
Name Glutathione S-transferase Mu 1
Gene Name GSTM1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7133
Glutathione S-transferase Mu 2
Name Glutathione S-transferase Mu 2
Gene Name GSTM2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0543

Predictions


Id Partner name Gene Name Score
714 Glutathione reductase, mitochondrial GSR 0.1519
904 Glutathione S-transferase P GSTP1 0.0913
2314 Triosephosphate isomerase TPI 0.0595
3417 Triosephosphate isomerase tpiA 0.0595
3443 Triosephosphate isomerase tpiA 0.0595
6346 Triosephosphate isomerase TPI1 0.0595
4031 Glutathione S-transferase A1 GSTA1 0.0501
3932 Glutathione S-transferase A2 GSTA2 0.0438
4041 Microsomal glutathione S-transferase 2 MGST2 0.0356
908 Glutathione S-transferase theta-1 GSTT1 0.0289
3947 Xanthine dehydrogenase/oxidase XDH 0.0253
6163 Copper-transporting ATPase 2 ATP7B 0.0224
6165 Copper-transporting ATPase 1 ATP7A 0.0224
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0211
6146 High affinity copper uptake protein 1 SLC31A1 0.021
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0193
1405 Thiopurine S-methyltransferase TPMT 0.0181
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.018
4035 Glutathione S-transferase Mu 5 GSTM5 0.017
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0168
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0166
1757 Myeloperoxidase MPO 0.016
900 Glutathione S-transferase A4 GSTA4 0.0151
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0151
903 Glutathione S-transferase A5 GSTA5 0.0151
4034 Glutaredoxin-1 GLRX 0.0151
4040 Glutathione peroxidase 7 GPX7 0.0151
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0151
1928 Leukotriene C4 synthase LTC4S 0.0151
4036 Glutathione peroxidase 6 GPX6 0.0151
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0151
4037 Hypothetical protein GPX1 0.0151
4297 Hypothetical protein SP_1951 0.0151
4521 Hypothetical protein BC_2969 0.0151
4540 Hypothetical protein TM_1070 0.0151
4555 Hypothetical protein MT1739 0.0151
4569 Hypothetical protein mshD 0.0151
4578 Hypothetical protein PA3270 0.0151
4747 Hypothetical protein PA3967 0.0151
5177 Hypothetical protein TM_0096 0.0151
5194 Hypothetical protein PA1204 0.0151
5240 Hypothetical protein Rv2991 0.0151
5370 Hypothetical protein TM_1158 0.0151
5710 Hypothetical protein Tb927.5.1360 0.0151
910 Epididymal secretory glutathione peroxidase GPX5 0.0151
911 Glutathione peroxidase 3 GPX3 0.0151
4029 Microsomal glutathione S-transferase 3 MGST3 0.0151
4032 Microsomal glutathione S-transferase 1 MGST1 0.0151
907 Glutathione peroxidase 2 GPX2 0.0151
4038 Glutathione peroxidase 4 GPX4 0.0151
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0151
906 Glutathione peroxidase 1 GPX1 0.0151
4033 S-formylglutathione hydrolase ESD 0.0151
4042 Glutathione transferase omega-2 GSTO2 0.0151
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0151
897 Glutathione S-transferase kappa 1 GSTK1 0.0139
898 Glutathione S-transferase A3 GSTA3 0.0137
3319 Hydroxyacylglutathione hydrolase HAGH 0.0137
909 Maleylacetoacetate isomerase GSTZ1 0.0134
901 Glutathione S-transferase Mu 4 GSTM4 0.0128
899 Glutathione S-transferase Mu 3 GSTM3 0.0122
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0119
905 Glutathione transferase omega-1 GSTO1 0.0114
6136 Multidrug resistance-associated protein 5 ABCC5 0.0107
207 Glutathione synthetase GSS 0.0103
5269 Glutathione synthetase gshB 0.0103
1313 Lactoylglutathione lyase GLO1 0.0102
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0096
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0096
4512 Cytochrome P450 3A4 CYP3A4 0.0077
6144 Solute carrier family 22 member 2 SLC22A2 0.0069
2164 Multidrug resistance-associated protein 4 ABCC4 0.0056
862 Multidrug resistance-associated protein 1 ABCC1 0.0054
6147 Solute carrier family 22 member 3 SLC22A3 0.0045
1898 Cytochrome P450 1B1 CYP1B1 0.0044
468 Cytochrome P450 4A11 CYP4A11 0.0042
6137 Multidrug resistance-associated protein 6 ABCC6 0.0042
6145 Solute carrier family 22 member 1 SLC22A1 0.0038
6024 Cytochrome P450 1A1 CYP1A1 0.0036
6013 Cytochrome P450 2E1 CYP2E1 0.0034
3923 Cholinesterase BCHE 0.0032
290 Prostaglandin G/H synthase 2 PTGS2 0.0031
4200 Cytochrome P450 1A2 CYP1A2 0.003
6030 Cytochrome P450 2B6 CYP2B6 0.0027
1588 Multidrug resistance protein 1 ABCB1 0.0023
4757 Cytochrome P450 2C9 CYP2C9 0.0023
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