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DB02344 - O-Sialic Acid (Chair Conformation)


Identification
Name O-Sialic Acid (Chair Conformation)
Accession Number DB02344 (EXPT02908)
Type small molecule
Description An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 309.2699
Groups experimental
Monoisotopic Weight 309.105981211
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


3-deoxy-manno-octulosonate cytidylyltransferase
Name 3-deoxy-manno-octulosonate cytidylyltransferase
Gene Name kpsU
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7611

Predictions


Id Partner name Gene Name Score
3120 3-deoxy-manno-octulosonate cytidylyltransferase kdsB 0.7611
2909 Cytidylate kinase cmk 0.0991
3692 Coenzyme A biosynthesis bifunctional protein coaBC coaBC 0.0967
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0914
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0914
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0914
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0914
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0914
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0914
2944 N-acylneuraminate cytidylyltransferase neuA 0.0784
7074 N-acylneuraminate cytidylyltransferase CMAS 0.0784
2697 Uridine-cytidine kinase 2 UCK2 0.0776
2967 CDP-paratose 2-epimerase rfbE 0.0682
4677 Glucose-1-phosphate cytidylyltransferase rfbF 0.0588
4676 CCA-adding enzyme cca 0.0588
3779 Alpha-2,3/8-sialyltransferase cst-II 0.0523
2991 Glycerol-3-phosphate cytidylyltransferase tagD 0.0512
3019 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ispD 0.0472
3344 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ispD 0.0472
3188 IspD/ispF bifunctional enzyme [Includes: 2-C-methyl-D-erythritol 4- phosphate cytidylyltransferase ispDF 0.0455
702 UMP-CMP kinase CMPK1 0.0331
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