DT-Web

DB02216 - S-Methylcysteine


Identification
Name S-Methylcysteine
Accession Number DB02216 (EXPT01076, EXPT02919)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 135.185
Groups experimental
Monoisotopic Weight 135.035399227
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cathepsin D
Name Cathepsin D
Gene Name CTSD
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2684
Methylated-DNA--protein-cysteine methyltransferase
Name Methylated-DNA--protein-cysteine methyltransferase
Gene Name MGMT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0964

Carriers


Predictions


Id Partner name Gene Name Score
6231 Pepsin A PGA3 0.1088
2853 14 kDa fatty acid-binding protein Not Available 0.0545
2211 Fatty acid-binding protein, heart FABP3 0.0503
6677 Myelin P2 protein PMP2 0.0475
3382 Glycolipid transfer protein GLTP 0.0437
171 Cysteine dioxygenase CDO-1 0.0424
774 Cysteinyl-tRNA synthetase, cytoplasmic CARS 0.0423
4064 Probable cysteinyl-tRNA synthetase, mitochondrial CARS2 0.0423
1314 Thiamine transporter 2 SLC19A3 0.0423
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0417
2009 Protein NOV homolog NOV 0.0417
3847 Neuroendocrine convertase 2 PCSK2 0.0417
1949 Carboxypeptidase E CPE 0.0417
3850 Synaptotagmin-like protein 4 SYTL4 0.0417
3848 Neuroendocrine convertase 1 PCSK1 0.0416
3846 Retinoblastoma-associated protein RB1 0.0416
1992 Vitamin D-binding protein GC 0.0379
2183 Fatty acid-binding protein, adipocyte FABP4 0.0375
3312 Fatty acid-binding protein, brain FABP7 0.0362
2155 Insulin-degrading enzyme IDE 0.0352
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0341
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.034
958 Insulin-like growth factor 1 receptor IGF1R 0.034
89 Cysteine sulfinic acid decarboxylase CSAD 0.031
626 Cysteine dioxygenase type 1 CDO1 0.0306
169 Cysteine desulfurase, mitochondrial NFS1 0.0297
36 Insulin receptor INSR 0.0296
868 Cystathionine gamma-lyase CTH 0.0287
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0284
207 Glutathione synthetase GSS 0.0282
5269 Glutathione synthetase gshB 0.0282
358 Cystathionine beta-synthase CBS 0.0272
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0269
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0231
6151 Monocarboxylate transporter 10 SLC16A10 0.0187
587 Serum albumin ALB 0.0166
2391 Ferrochelatase hemH 0.0165
6502 Ferrochelatase DKFZp686P18130 0.0165
1591 Ferrochelatase, mitochondrial FECH 0.0165
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0145
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0144
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0144
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0144
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0144
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0144
6559 Cytochrome c oxidase subunit 2 ctaC 0.0144
6669 Cytochrome c oxidase subunit 2 ctaC 0.0144
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0144
6493 Cytochrome c oxidase subunit 6C COX6C 0.0144
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0144
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0144
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0144
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0144
6558 Cytochrome c oxidase subunit 1 ctaD 0.0144
3587 Gastrotropin FABP6 0.0133
2540 Choloylglycine hydrolase cbh 0.0133
6500 Phospholipase A2 PLA2G1B 0.0131
4200 Cytochrome P450 1A2 CYP1A2 0.0126
3809 Estrogen-related receptor gamma ESRRG 0.0099
4604 Liver carboxylesterase 1 CES1 0.0093
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0089
517 Alcohol dehydrogenase 1C ADH1C 0.0085
6141 Sodium/bile acid cotransporter SLC10A1 0.0071
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0061
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0055
776 Bile salt export pump ABCB11 0.0055
2164 Multidrug resistance-associated protein 4 ABCC4 0.0052
6143 Solute carrier family 22 member 7 SLC22A7 0.0052
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0051
862 Multidrug resistance-associated protein 1 ABCC1 0.0051
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.005
4878 Glycoprotein hormones alpha chain CGA 0.0049
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0049
4880 Membrane cofactor protein CD46 0.0049
4877 Beta-mannanase man 0.0049
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0049
4889 Ig epsilon chain C region IGHE 0.0049
4850 Beta-2-glycoprotein 1 APOH 0.0049
757 Fusion glycoprotein F0 F 0.0049
4875 Fusion glycoprotein F0 F 0.0049
442 Envelope glycoprotein gp41 0.0049
4859 Envelope glycoprotein env 0.0049
4189 Alpha-galactosidase A GLA 0.0049
4869 Major capsid protein A430L 0.0049
1072 Granzyme B GZMB 0.0049
4852 Reticulon-4 receptor RTN4R 0.0049
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0049
1354 Beta-glucuronidase GUSB 0.0049
4856 CD209 antigen CD209 0.0049
4845 ADAM 33 ADAM33 0.0049
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0049
4721 Beta-1,4-mannanase manA 0.0049
3352 Structural polyprotein Not Available 0.0049
3628 Structural polyprotein Not Available 0.0049
4892 Structural polyprotein Not Available 0.0049
6142 Solute carrier family 22 member 8 SLC22A8 0.0048
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0046
1184 Interferon beta IFNB1 0.0043
6858 Inactive carboxylesterase 4 CES1P1 0.0043
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0043
4861 Interleukin-6 receptor alpha chain IL6R 0.0043
1379 Interleukin-12 subunit beta IL12B 0.0043
793 T-cell surface antigen CD2 CD2 0.0043
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0043
4890 Hemagglutinin HA 0.0043
6566 Hemagglutinin Not Available 0.0043
3837 Cytokine receptor common beta chain CSF2RB 0.0043
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0043
3444 Cyanovirin-N Not Available 0.0039
1859 Prostatic acid phosphatase ACPP 0.0039
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0039
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0039
3140 Hemagglutinin-neuraminidase HN 0.0039
3609 Hemagglutinin-neuraminidase HN 0.0039
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0039
2297 Genome polyprotein Not Available 0.0039
2322 Genome polyprotein Not Available 0.0039
2694 Genome polyprotein Not Available 0.0039
2719 Genome polyprotein Not Available 0.0039
2860 Genome polyprotein Not Available 0.0039
2928 Genome polyprotein Not Available 0.0039
3160 Genome polyprotein Not Available 0.0039
3260 Genome polyprotein Not Available 0.0039
4783 Genome polyprotein Not Available 0.0039
5726 Genome polyprotein Not Available 0.0039
5779 Genome polyprotein Not Available 0.0039
5867 Genome polyprotein Not Available 0.0039
6253 Genome polyprotein Not Available 0.0039
6301 Genome polyprotein Not Available 0.0039
6380 Genome polyprotein Not Available 0.0039
6381 Genome polyprotein Not Available 0.0039
6437 Genome polyprotein Not Available 0.0039
6520 Genome polyprotein Not Available 0.0039
6521 Genome polyprotein Not Available 0.0039
6652 Genome polyprotein Not Available 0.0039
6734 Genome polyprotein Not Available 0.0039
6735 Genome polyprotein Not Available 0.0039
6736 Genome polyprotein Not Available 0.0039
6737 Genome polyprotein Not Available 0.0039
6738 Genome polyprotein Not Available 0.0039
6739 Genome polyprotein Not Available 0.0039
6744 Genome polyprotein Not Available 0.0039
6748 Genome polyprotein Not Available 0.0039
6894 Genome polyprotein Not Available 0.0039
6898 Genome polyprotein Not Available 0.0039
554 Low-density lipoprotein receptor LDLR 0.0037
4666 Fucose-binding lectin PA-IIL lecB 0.0037
2372 Bifunctional tail protein 9 0.0037
4787 Envelope glycoprotein gp160 env 0.0037
4820 Envelope glycoprotein gp160 env 0.0037
5727 Envelope glycoprotein gp160 env 0.0037
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0036
1588 Multidrug resistance protein 1 ABCB1 0.0036
852 Heparin cofactor 2 SERPIND1 0.0036
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0035
3480 Mannan endo-1,4-beta-mannosidase manA 0.0034
64 Neuraminidase NA 0.0034
641 Neuraminidase NA 0.0034
2676 Neuraminidase NA 0.0034
3026 Neuraminidase NA 0.0034
3519 Neuraminidase NA 0.0034
6007 Neuraminidase NA 0.0034
1439 Lactotransferrin LTF 0.0033
595 Fibrinogen alpha chain FGA 0.0033
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0032
2430 Chondroitinase B cslB 0.0031
6307 Ig gamma-2 chain C region IGHG2 0.0031
2581 Chondroitinase AC cslA 0.0031
6847 Lactase-phlorizin hydrolase LCT 0.003
2207 Rhodopsin RHO 0.0028
309 Antithrombin-III SERPINC1 0.0028
3814 Complement C1r subcomponent C1R 0.0027
4785 Ig gamma-1 chain C region IGHG1 0.0025
76 Nitric-oxide synthase, brain NOS1 0.0025
952 Dipeptidyl peptidase 4 DPP4 0.0022
3923 Cholinesterase BCHE 0.0018
20 Prostaglandin G/H synthase 1 PTGS1 0.0016
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