DT-Web

DB02032 - 1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid


Identification
Name 1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid
Accession Number DB02032 (EXPT02137)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 217.285
Groups experimental
Monoisotopic Weight 217.077264041
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Angiotensin-converting enzyme
Name Angiotensin-converting enzyme
Gene Name ACE
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.9968
FEZ-1 protein
Name FEZ-1 protein
Gene Name blaFEZ-1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2683
Carbapenem-hydrolyzing beta-lactamase blaB-1
Name Carbapenem-hydrolyzing beta-lactamase blaB-1
Gene Name blaB1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2685
Metallo-beta-lactamase L1
Name Metallo-beta-lactamase L1
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 2.4037
Beta-lactamase
Name Beta-lactamase
Gene Name cphA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2686
Organic hydroperoxide resistance protein, putative
Name Organic hydroperoxide resistance protein, putative
Gene Name VC_A1006
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2689

Predictions


Id Partner name Gene Name Score
332 Beta-lactamase blaZ 1.2686
2478 Beta-lactamase ampC 1.2686
2613 Beta-lactamase ampC 1.2686
2635 Beta-lactamase ampC 1.2686
2700 Beta-lactamase penP 1.2686
5445 Beta-lactamase blaB 1.2686
6019 Beta-lactamase SHV-7 1.2686
2618 Methyl-accepting chemotaxis protein II tar 0.1795
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.1789
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.1375
1385 Angiotensin-converting enzyme 2 ACE2 0.0605
294 Neprilysin MME 0.0432
1588 Multidrug resistance protein 1 ABCB1 0.0349
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0231
3923 Cholinesterase BCHE 0.0227
3917 Methylenetetrahydrofolate reductase MTHFR 0.0182
4604 Liver carboxylesterase 1 CES1 0.0158
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0142
3626 Probable polysaccharide deacetylase pdaA pdaA 0.0138
4787 Envelope glycoprotein gp160 env 0.0125
4820 Envelope glycoprotein gp160 env 0.0125
5727 Envelope glycoprotein gp160 env 0.0125
707 72 kDa type IV collagenase MMP2 0.0119
1373 Glucosylceramidase GBA 0.0114
4666 Fucose-binding lectin PA-IIL lecB 0.0114
1729 Solute carrier family 22 member 6 SLC22A6 0.011
3140 Hemagglutinin-neuraminidase HN 0.0104
3609 Hemagglutinin-neuraminidase HN 0.0104
65 Matrix metalloproteinase-9 Not Available 0.0096
4785 Ig gamma-1 chain C region IGHG1 0.0074
6143 Solute carrier family 22 member 7 SLC22A7 0.0068
474 Acetylcholinesterase ACHE 0.006
6142 Solute carrier family 22 member 8 SLC22A8 0.006
587 Serum albumin ALB 0.0054
4119 Cytochrome P450 2D6 CYP2D6 0.0045
4512 Cytochrome P450 3A4 CYP3A4 0.0041
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