DT-Web

DB01839 - 1,2-Propanediol


Identification
Name 1,2-Propanediol
Accession Number DB01839 (EXPT02572)
Type small molecule
Description A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 76.0944
Groups experimental
Monoisotopic Weight 76.0524295
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Coagulation factor XIII A chain
Name Coagulation factor XIII A chain
Gene Name F13A1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2572
Haloalkane dehalogenase
Name Haloalkane dehalogenase
Gene Name linB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.2046
Clavaminate synthase 1
Name Clavaminate synthase 1
Gene Name cs1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.3843
Lactaldehyde reductase
Name Lactaldehyde reductase
Gene Name fucO
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8832
Glycerol dehydratase
Name Glycerol dehydratase
Gene Name dhaB1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9263

Predictions


Id Partner name Gene Name Score
4561 Beta-agarase A agaA 0.3536
2885 Carboxyethyl-arginine beta-lactam-synthase bls 0.2681
6316 ADP-ribosylation factor 1 ARF1 0.1095
4593 ADP compounds hydrolase nudE nudE 0.0979
2460 ADP-ribose pyrophosphatase nudF 0.0852
4349 ADP-ribose pyrophosphatase ndx4 0.0852
3108 CDP-glucose 4,6-dehydratase rfbG 0.0852
4037 Hypothetical protein GPX1 0.0786
4297 Hypothetical protein SP_1951 0.0786
4521 Hypothetical protein BC_2969 0.0786
4540 Hypothetical protein TM_1070 0.0786
4555 Hypothetical protein MT1739 0.0786
4569 Hypothetical protein mshD 0.0786
4578 Hypothetical protein PA3270 0.0786
4747 Hypothetical protein PA3967 0.0786
5177 Hypothetical protein TM_0096 0.0786
5194 Hypothetical protein PA1204 0.0786
5240 Hypothetical protein Rv2991 0.0786
5370 Hypothetical protein TM_1158 0.0786
5710 Hypothetical protein Tb927.5.1360 0.0786
6790 Elongation factor 2 EEF2 0.0741
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0709
2769 P-hydroxybenzoate hydroxylase pobA 0.0709
2809 P-hydroxybenzoate hydroxylase pobA 0.0709
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0673
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0673
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0673
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0673
3986 Protein-glutamine gamma-glutamyltransferase 6 TGM6 0.0217
3990 Protein-glutamine gamma-glutamyltransferase 4 TGM4 0.0217
3988 Protein-glutamine gamma-glutamyltransferase K TGM1 0.0217
3983 Protein-glutamine gamma-glutamyltransferase 5 TGM5 0.0217
3992 Protein-glutamine gamma-glutamyltransferase Z TGM7 0.0217
1008 CTP synthase 1 CTPS 0.0217
3985 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 0.0217
3989 Glutaminyl-tRNA synthetase QARS 0.0217
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0197
5 Glutaminase liver isoform, mitochondrial GLS2 0.0181
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0181
917 Glutaminase kidney isoform, mitochondrial GLS 0.0181
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0181
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0181
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0181
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0181
5261 Phosphoribosylformylglycinamidine synthase purL 0.0181
263 Neutral amino acid transporter B(0) SLC1A5 0.0179
3971 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase CAD 0.0175
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0168
413 Amidophosphoribosyltransferase PPAT 0.0164
2515 Amidophosphoribosyltransferase purF 0.0164
3714 Amidophosphoribosyltransferase purF 0.0164
314 System N amino acid transporter 1 SLC38A3 0.016
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0156
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0151
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.014
3426 Glutamine synthetase glnA 0.0127
3987 Glutamine synthetase GLUL 0.0127
6151 Monocarboxylate transporter 10 SLC16A10 0.0103
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