| Name |
Profilin-2 |
| Synonyms |
9054 |
| Gene name |
PFN2 |
| General function |
Involved in actin binding |
| Specific function |
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG |
| Gene sequence |
+ ...
ATGGCCGGTTGGCAGAGCTACGTGGATAACCTGATGTGCGATGGCTGCTGCCAGGAGGCCGCCATTGTCGGCTACTGCGACGCCAAATACGTCTGGGCAGCCACGGCCGGGGGCGTCTTTCAGAGCATTACGCCAATAGAAATAGATATGATTGTAGGAAAAGACCGGGAAGGTTTCTTTACCAACGGTTTGACTCTTGGCGCGAAGAAATGCTCAGTGATCAGAGATAGTCTATACGTCGATGGTGACTGCACAATGGACATCCGGACAAAGAGTCAAGGTGGGGAGCCAACATACAATGTGGCTGTCGGCAGAGCTGGTAGAGCATTGGTTATAGTCATGGGAAAGGAAGGTGTCCACGGAGGCACACTTAACAAGAAAGCATATGAACTCGCTTTATACCTGAGGAGGTCTGATGTGTAA
|
| Protein sequence |
+ ...
MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
|
| GO Classification |
| component |
| intracellular non-membrane-bound organelle |
| cytoskeleton |
| actin cytoskeleton |
| organelle |
| non-membrane-bound organelle |
| function |
| cytoskeletal protein binding |
| actin binding |
| binding |
| protein binding |
| process |
| actin filament-based process |
| physiological process |
| actin cytoskeleton organization and biogenesis |
| cellular physiological process |
| cell organization and biogenesis |
| organelle organization and biogenesis |
| cytoskeleton organization and biogenesis |
|
|
See more information at →
www.drugbank.ca
|