| Name |
Tyrosine-protein phosphatase yopH |
| Synonyms |
4346 |
| Gene name |
yopH |
| General function |
Involved in protein tyrosine phosphatase activity |
| Specific function |
Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of yopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages |
| Gene sequence |
+ ...
ATGAACTTATCATTAAGCGATCTTCATCGTCAGGTATCTCGATTGGTGCAGCAAGAGAGCGGTGATTGTACCGGGAAATTAAGAGGTAACGTTGCTGCCAATAAAGAAACTACCTTTCAAGGTTTGACCATAGCCAGTGGTGCCAGAGAGTCAGAAAAAGTATTTGCTCAAACTGTACTAAGCCACGTAGCAAATATTGTTCTAACTCAAGAAGATACCGCTAAGCTATTGCAAAGCACGGTAAAGCATAATTTGAATAATTATGAATTAAGAAGTGTCGGCAATGGTAATAGTGTACTTGTCAGTTTACGTAGTGACCAAATGACACTACAAGACGCCAAAGTGCTGTTGGAGGCTGCATTGCGACAAGAGTCGGGAGCGAGGGGGCATGTATCATCTCATTCACATTCAGTCCTTCACGCACCGGGAACCCCGGTGCGTGAAGGACTGCGTTCACATCTAGACCCCAGAACACCACCGTTGCCACCGCGTGAACGACCACACACTTCTGGCCATCACGGGGCTGGCGAAGCCAGAGCCACCGCACCAAGCACTGTTTCTCCTTATGGCCCAGAAGCGCGCGCAGAACTCAGCAGCCGCCTCACCACATTGCGCAATACGCTGGCGCCAGCAACGAATGATCCGCGTTACTTACAAGCCTGCGGCGGTGAAAAGCTAAACCGATTTAGAGATATTCAATGCTGTCGGCAAACCGCAGTACGCGCCGATCTTAATGCCAATTACATCCAGGTCGGTAACACTCGTACCATAGCGTGCCAGTATCCGCTACAATCTCAACTTGAAAGCCATTTCCGTATGCTGGCAGAAAACCGAACGCCAGTGTTGGCTGTTTTAGCGTCCAGTTCTGAGATAGCCAATCAAAGATTCGGTATGCCAGATTATTTCCGCCAGAGTGGTACCTATGGCAGTATCACTGTAGAGTCTAAAATGACTCAGCAAGTTGGTCTCGGTGACGGGATTATGGCAGATATGTATACTTTAACGATTCGTGAAGCGGGTCAAAAAACAATTTCTGTTCCTGTGGTTCATGTTGGCAATTGGCCCGATCAGACCGCAGTCAGCTCTGAAGTTACCAAGGCACTCGCTTCACTGGTAGATCAAACAGCAGAAACAAAACGCAATATGTATGAAAGCAAAGGAAGTTCAGCGGTAGCAGATGACTCCAAATTACGGCCGGTAATACATTGCCGTGCGGGTGTTGGCCGTACTGCGCAACTGATTGGCGCAATGTGCATGAATGATAGTCGTAATAGTCAGTTAAGCGTAGAAGATATGGTCAGCCAAATGCGAGTACAAAGAAATGGTATTATGGTACAAAAAGATGAGCAACTTGATGTTCTGATTAAGTTGGCTGAAGGACAAGGGCGACCATTATTAAATAGCTAA
|
| Protein sequence |
+ ...
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
|
| GO Classification |
| function |
| hydrolase activity, acting on ester bonds |
| phosphoric ester hydrolase activity |
| phosphoric monoester hydrolase activity |
| phosphoprotein phosphatase activity |
| protein tyrosine phosphatase activity |
| catalytic activity |
| hydrolase activity |
| process |
| physiological process |
| protein amino acid dephosphorylation |
| metabolism |
| macromolecule metabolism |
| biopolymer metabolism |
| biopolymer modification |
| protein modification |
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