Identification | |
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Name | Dehydroascorbic Acid |
Accession Number | DB08830 |
Type | small molecule |
Description | Dehydroascorbic acid is made from the oxidation of ascorbic acid. This reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic acid. Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans. In the body, both dehydroascorbic acid and ascorbic acid have similar biological activity as antivirals but dehydroascorbic acid also has neuroprotective effects. Currently dehydroascorbic acid is an experimental drug with no known approved indications. |
Structure |
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Categories (*) | |
Molecular Weight | 174.1082 |
Groups | experimental |
Monoisotopic Weight | 174.016437924 |
Pharmacology | |
Indication | There is no approved indication for dehydroascorbic acid, but it has potential therapeutic use in patients with certain viruses and ischemic stroke. |
Mechanism of action | Even though dehydroascorbic acid and ascorbic acid have similar effects, their mechanism of action seems to be different. The exact mechanism of action is still being investigated, but some have been elucidated. Concerning dehydroascorbic acid's antiviral effect against herpes simplex virus type 1, it is suggested that dehydroascorbic acid acts after replication of viral DNA and prevents the assembly of progeny virus particles. |
Absorption | Not Available |
Protein binding | Not Available |
Biotransformation | Not Available |
Route of elimination | Not Available |
Toxicity | Not Available |
Affected organisms |
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Interactions | |
Drug Interactions | Not Available |
Food Interactions | Not Available |
Solute carrier family 2, facilitated glucose transporter member 1 | |
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Name | Solute carrier family 2, facilitated glucose transporter member 1 |
Gene Name | SLC2A1 |
Actions | Not Available |
References |
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DTHybrid score | 1.2198 |
Id | Partner name | Gene Name | Score |
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6023 | Cytochrome P450 11B2, mitochondrial | CYP11B2 | 0.0531 |
805 | Cytochrome P450 11B1, mitochondrial | CYP11B1 | 0.0446 |
629 | Alpha-2B adrenergic receptor | ADRA2B | 0.0389 |
3811 | Cytochrome P450 19A1 | CYP19A1 | 0.0378 |
872 | Gamma-aminobutyric-acid receptor subunit alpha-1 | GABRA1 | 0.0319 |