DT-Web

DB08770 - 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol


Identification
Name 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol
Accession Number DB08770
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 337.336
Groups experimental
Monoisotopic Weight 337.128722759
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenosine A2a receptor
Name Adenosine A2a receptor
Gene Name ADORA2A
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5068

Predictions


Id Partner name Gene Name Score
16 Adenosine A1 receptor ADORA1 0.1541
268 Adenosine A2b receptor ADORA2B 0.0878
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0565
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0499
4200 Cytochrome P450 1A2 CYP1A2 0.0343
4122 Histone deacetylase 2 HDAC2 0.0268
1830 5'-nucleotidase NT5E 0.0234
390 Adenosine A3 receptor ADORA3 0.0233
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.022
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.022
6013 Cytochrome P450 2E1 CYP2E1 0.0207
3957 Adenosine deaminase ADA 0.0202
691 cAMP-specific 3',5'-cyclic phosphodiesterase 7B PDE7B 0.0199
6021 Adenosine kinase ADK 0.0185
779 High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A PDE7A 0.0182
6171 Solute carrier family 28 member 3 SLC28A3 0.018
6143 Solute carrier family 22 member 7 SLC22A7 0.0163
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.0154
144 Hemoglobin subunit alpha HBA1 0.0146
4119 Cytochrome P450 2D6 CYP2D6 0.0131
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0124
4512 Cytochrome P450 3A4 CYP3A4 0.0118
1588 Multidrug resistance protein 1 ABCB1 0.0103
1898 Cytochrome P450 1B1 CYP1B1 0.0103
3811 Cytochrome P450 19A1 CYP19A1 0.01
474 Acetylcholinesterase ACHE 0.0099
814 Ryanodine receptor 1 RYR1 0.0098
3923 Cholinesterase BCHE 0.0092
6024 Cytochrome P450 1A1 CYP1A1 0.0083
4924 Cytochrome P450 2C8 CYP2C8 0.0072
4757 Cytochrome P450 2C9 CYP2C9 0.0066
6107 Cytochrome P450 3A7 CYP3A7 0.0042
4118 Cytochrome P450 3A5 CYP3A5 0.004
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