DT-Web

DB08741 - 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine


Identification
Name 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
Accession Number DB08741
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 354.403
Groups experimental
Monoisotopic Weight 354.16919059
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Dihydrofolate reductase
Name Dihydrofolate reductase
Gene Name folA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.0835

Predictions


Id Partner name Gene Name Score
6236 Trimethoprim-sensitive dihydrofolate reductase dfrB 0.1505
365 Dihydrofolate reductase DHFR 0.0835
2381 Dihydrofolate reductase DFR1 0.0835
2833 Dihydrofolate reductase Not Available 0.0835
2931 Dihydrofolate reductase folA 0.0835
3544 Dihydrofolate reductase folA 0.0835
3682 Dihydrofolate reductase folA 0.0835
6756 Dihydrofolate reductase dfrA 0.0835
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