DT-Web

DB08386 - 2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline


Identification
Name 2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline
Accession Number DB08386
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 378.4259
Groups experimental
Monoisotopic Weight 378.148061218
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Gene Name PDE10A
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0564
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0422
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0416
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0402
7 Nitric oxide synthase, inducible NOS2 0.0288
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0249
20 Prostaglandin G/H synthase 1 PTGS1 0.0198
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0188
3957 Adenosine deaminase ADA 0.0176
6136 Multidrug resistance-associated protein 5 ABCC5 0.0152
2164 Multidrug resistance-associated protein 4 ABCC4 0.0128
4512 Cytochrome P450 3A4 CYP3A4 0.0109
1588 Multidrug resistance protein 1 ABCB1 0.0089
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