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DB08175 - (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID


Identification
Name (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID
Accession Number DB08175
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 268.3917
Groups experimental
Monoisotopic Weight 268.203844762
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Nuclear receptor coactivator 2
Name Nuclear receptor coactivator 2
Gene Name NCOA2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0553
Retinoic acid receptor RXR-beta
Name Retinoic acid receptor RXR-beta
Gene Name RXRB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7089
Oxysterols receptor LXR-alpha
Name Oxysterols receptor LXR-alpha
Gene Name NR1H3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.9468

Predictions


Id Partner name Gene Name Score
136 Estrogen receptor ESR1 0.4099
459 Retinoic acid receptor RXR-alpha RXRA 0.3045
2907 Oxysterols receptor LXR-beta NR1H2 0.1153
780 Retinoic acid receptor RXR-gamma RXRG 0.0993
6228 Nuclear receptor coactivator 1 NCOA1 0.0862
229 Retinoic acid receptor beta RARB 0.0852
730 Retinoic acid receptor alpha RARA 0.0838
162 Retinoic acid receptor gamma-1 RARG 0.0828
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0729
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0379
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0363
5934 Cytochrome P450 26A1 CYP26A1 0.029
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0208
146 Androgen receptor AR 0.0184
614 Progesterone receptor PGR 0.0178
331 Retinol-binding protein I, cellular RBP1 0.0171
4924 Cytochrome P450 2C8 CYP2C8 0.0143
4757 Cytochrome P450 2C9 CYP2C9 0.0132
4512 Cytochrome P450 3A4 CYP3A4 0.0116
719 Retinoic acid receptor responder protein 1 RARRES1 0.0089
770 Retinoic acid-induced protein 3 GPRC5A 0.0089
3811 Cytochrome P450 19A1 CYP19A1 0.0088
4200 Cytochrome P450 1A2 CYP1A2 0.0083
1588 Multidrug resistance protein 1 ABCB1 0.0081
992 Protein tyrosine kinase 2 beta PTK2B 0.0078
84 Nuclear receptor 0B1 NR0B1 0.0072
569 Retinal dehydrogenase 2 ALDH1A2 0.0071
587 Serum albumin ALB 0.007
611 Retinal dehydrogenase 1 ALDH1A1 0.0068
869 Estrogen receptor beta ESR2 0.0058
373 Transthyretin TTR 0.0055
468 Cytochrome P450 4A11 CYP4A11 0.005
817 DNA topoisomerase 2-alpha TOP2A 0.0044
6106 Cytochrome P450 2C18 CYP2C18 0.0042
862 Multidrug resistance-associated protein 1 ABCC1 0.004
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0037
5718 Cytochrome P450 2A6 CYP2A6 0.0034
6024 Cytochrome P450 1A1 CYP1A1 0.0033
6030 Cytochrome P450 2B6 CYP2B6 0.0031
6107 Cytochrome P450 3A7 CYP3A7 0.0031
4118 Cytochrome P450 3A5 CYP3A5 0.0029
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