Identification | |
---|---|
Name | 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE |
Accession Number | DB08159 |
Type | small molecule |
Description | Not Available |
Structure |
|
Categories (*) | |
Molecular Weight | 333.3374 |
Groups | experimental |
Monoisotopic Weight | 333.100107973 |
Pharmacology | |
Indication | Not Available |
Mechanism of action | Not Available |
Absorption | Not Available |
Protein binding | Not Available |
Biotransformation | Not Available |
Route of elimination | Not Available |
Toxicity | Not Available |
Affected organisms | Not Available |
Interactions | |
Drug Interactions | Not Available |
Food Interactions | Not Available |
DNA topoisomerase 1 | |
---|---|
Name | DNA topoisomerase 1 |
Gene Name | TOP1 |
Pharmacological action | unknown |
Actions | Not Available |
References |
|
DTHybrid score | 0.9971 |
Id | Partner name | Gene Name | Score |
---|---|---|---|
3552 | DNA topoisomerase 1 | topA | 0.9971 |
4180 | DNA-(apurinic or apyrimidinic site) lyase | APEX1 | 0.1088 |
102 | DNA topoisomerase I, mitochondrial | TOP1MT | 0.0647 |
1732 | ATP-binding cassette sub-family G member 2 | ABCG2 | 0.0608 |
1588 | Multidrug resistance protein 1 | ABCB1 | 0.0467 |
817 | DNA topoisomerase 2-alpha | TOP2A | 0.0423 |
4512 | Cytochrome P450 3A4 | CYP3A4 | 0.0178 |
4604 | Liver carboxylesterase 1 | CES1 | 0.0086 |
6018 | UDP-glucuronosyltransferase 1-9 | UGT1A9 | 0.0076 |
6022 | UDP-glucuronosyltransferase 1-1 | UGT1A1 | 0.0071 |
6147 | Solute carrier family 22 member 3 | SLC22A3 | 0.007 |
3923 | Cholinesterase | BCHE | 0.0065 |
862 | Multidrug resistance-associated protein 1 | ABCC1 | 0.0064 |
1490 | Solute carrier organic anion transporter family member 1B1 | SLCO1B1 | 0.0064 |
1735 | Canalicular multispecific organic anion transporter 1 | ABCC2 | 0.0059 |
587 | Serum albumin | ALB | 0.0055 |
6030 | Cytochrome P450 2B6 | CYP2B6 | 0.0054 |
6107 | Cytochrome P450 3A7 | CYP3A7 | 0.0052 |
4118 | Cytochrome P450 3A5 | CYP3A5 | 0.005 |