DT-Web

DB08063 - 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE


Identification
Name 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE
Accession Number DB08063
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 384.4272
Groups experimental
Monoisotopic Weight 384.147392516
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Retinoic acid receptor RXR-alpha
Name Retinoic acid receptor RXR-alpha
Gene Name RXRA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5203
Oxysterols receptor LXR-alpha
Name Oxysterols receptor LXR-alpha
Gene Name NR1H3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.826

Predictions


Id Partner name Gene Name Score
88 Retinoic acid receptor RXR-beta RXRB 0.3518
6241 Nuclear receptor coactivator 2 NCOA2 0.2714
780 Retinoic acid receptor RXR-gamma RXRG 0.0923
6228 Nuclear receptor coactivator 1 NCOA1 0.077
2907 Oxysterols receptor LXR-beta NR1H2 0.0739
229 Retinoic acid receptor beta RARB 0.0598
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0594
730 Retinoic acid receptor alpha RARA 0.058
162 Retinoic acid receptor gamma-1 RARG 0.0553
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0443
6350 Nuclear receptor subfamily 1 group I member 3 NR1I3 0.0432
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0333
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0286
5934 Cytochrome P450 26A1 CYP26A1 0.0283
331 Retinol-binding protein I, cellular RBP1 0.0164
4757 Cytochrome P450 2C9 CYP2C9 0.016
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0138
587 Serum albumin ALB 0.0134
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0112
4512 Cytochrome P450 3A4 CYP3A4 0.0094
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.009
3811 Cytochrome P450 19A1 CYP19A1 0.0089
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0087
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0084
290 Prostaglandin G/H synthase 2 PTGS2 0.0072
20 Prostaglandin G/H synthase 1 PTGS1 0.0068
1729 Solute carrier family 22 member 6 SLC22A6 0.0063
4200 Cytochrome P450 1A2 CYP1A2 0.0055
1588 Multidrug resistance protein 1 ABCB1 0.0053
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