DT-Web

DB07929 - N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE


Identification
Name N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE
Accession Number DB07929
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 396.4794
Groups experimental
Monoisotopic Weight 396.204907394
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Oxysterols receptor LXR-alpha
Name Oxysterols receptor LXR-alpha
Gene Name NR1H3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8952
Retinoic acid receptor RXR-beta
Name Retinoic acid receptor RXR-beta
Gene Name RXRB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6763

Predictions


Id Partner name Gene Name Score
459 Retinoic acid receptor RXR-alpha RXRA 0.2249
6241 Nuclear receptor coactivator 2 NCOA2 0.1983
780 Retinoic acid receptor RXR-gamma RXRG 0.0993
2907 Oxysterols receptor LXR-beta NR1H2 0.098
229 Retinoic acid receptor beta RARB 0.0852
730 Retinoic acid receptor alpha RARA 0.0838
162 Retinoic acid receptor gamma-1 RARG 0.0828
6228 Nuclear receptor coactivator 1 NCOA1 0.0672
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0619
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0363
5934 Cytochrome P450 26A1 CYP26A1 0.029
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0208
331 Retinol-binding protein I, cellular RBP1 0.0171
4924 Cytochrome P450 2C8 CYP2C8 0.0143
4757 Cytochrome P450 2C9 CYP2C9 0.0132
4512 Cytochrome P450 3A4 CYP3A4 0.0116
719 Retinoic acid receptor responder protein 1 RARRES1 0.0089
770 Retinoic acid-induced protein 3 GPRC5A 0.0089
3811 Cytochrome P450 19A1 CYP19A1 0.0088
84 Nuclear receptor 0B1 NR0B1 0.0072
569 Retinal dehydrogenase 2 ALDH1A2 0.0071
587 Serum albumin ALB 0.007
611 Retinal dehydrogenase 1 ALDH1A1 0.0068
4200 Cytochrome P450 1A2 CYP1A2 0.0054
1588 Multidrug resistance protein 1 ABCB1 0.0053
468 Cytochrome P450 4A11 CYP4A11 0.005
6106 Cytochrome P450 2C18 CYP2C18 0.0042
5718 Cytochrome P450 2A6 CYP2A6 0.0034
6024 Cytochrome P450 1A1 CYP1A1 0.0033
6030 Cytochrome P450 2B6 CYP2B6 0.0031
6107 Cytochrome P450 3A7 CYP3A7 0.0031
4118 Cytochrome P450 3A5 CYP3A5 0.0029
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