DT-Web

DB07919 - 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE


Identification
Name 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE
Accession Number DB07919
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 212.2472
Groups experimental
Monoisotopic Weight 212.094963016
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.3828

Predictions


Id Partner name Gene Name Score
3939 Amine oxidase [flavin-containing] B MAOB 0.1689
824 Sodium-dependent serotonin transporter SLC6A4 0.0339
511 5-hydroxytryptamine 1F receptor HTR1F 0.0325
713 Sodium-dependent dopamine transporter SLC6A3 0.032
4200 Cytochrome P450 1A2 CYP1A2 0.032
725 5-hydroxytryptamine 1D receptor HTR1D 0.0262
885 5-hydroxytryptamine 1B receptor HTR1B 0.0258
4119 Cytochrome P450 2D6 CYP2D6 0.0239
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0217
131 Synaptic vesicular amine transporter SLC18A2 0.0179
6016 Cytochrome P450 2C19 CYP2C19 0.0169
556 Alpha-1A adrenergic receptor ADRA1A 0.0164
318 Alpha-2A adrenergic receptor ADRA2A 0.0163
3810 Catechol O-methyltransferase COMT 0.0147
4757 Cytochrome P450 2C9 CYP2C9 0.0144
320 5-hydroxytryptamine 1A receptor HTR1A 0.0143
1588 Multidrug resistance protein 1 ABCB1 0.0116
193 Beta-1 adrenergic receptor ADRB1 0.0113
5698 Riboflavin synthase alpha chain ribE 0.0105
408 Riboflavin kinase RFK 0.0101
4512 Cytochrome P450 3A4 CYP3A4 0.01
6013 Cytochrome P450 2E1 CYP2E1 0.0097
23 D(1A) dopamine receptor DRD1 0.0094
146 Androgen receptor AR 0.0089
3811 Cytochrome P450 19A1 CYP19A1 0.0088
654 Flavin reductase BLVRB 0.0075
4924 Cytochrome P450 2C8 CYP2C8 0.0074
789 Alpha-1D adrenergic receptor ADRA1D 0.0068
502 5-hydroxytryptamine 2A receptor HTR2A 0.0067
3917 Methylenetetrahydrofolate reductase MTHFR 0.0066
6147 Solute carrier family 22 member 3 SLC22A3 0.0065
5718 Cytochrome P450 2A6 CYP2A6 0.0062
632 Alpha-1B adrenergic receptor ADRA1B 0.0061
766 Beta-2 adrenergic receptor ADRB2 0.0059
1757 Myeloperoxidase MPO 0.0059
6030 Cytochrome P450 2B6 CYP2B6 0.0059
378 Alpha-2C adrenergic receptor ADRA2C 0.0053
629 Alpha-2B adrenergic receptor ADRA2B 0.0052
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0051
118 Organic cation/carnitine transporter 2 SLC22A5 0.0047
6031 Cytochrome P450 3A43 CYP3A43 0.0042
831 D(2) dopamine receptor DRD2 0.0042
3913 Glutamic acid decarboxylase GAD65 0.0042
1636 Trace amine-associated receptor 1 TAAR1 0.0041
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0041
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0041
1729 Solute carrier family 22 member 6 SLC22A6 0.0041
1656 CYP2B protein CYP2B 0.0039
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0039
1483 Membrane copper amine oxidase AOC3 0.0039
1517 Beta-3 adrenergic receptor ADRB3 0.0037
6014 Cytochrome P450 2A13 CYP2A13 0.0036
436 5-hydroxytryptamine 2B receptor HTR2B 0.0036
735 Alanine aminotransferase 1 GPT 0.0034
3904 Alanine aminotransferase 2 GPT2 0.0034
6145 Solute carrier family 22 member 1 SLC22A1 0.0034
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0032
590 5-hydroxytryptamine 2C receptor HTR2C 0.0031
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0031
474 Acetylcholinesterase ACHE 0.003
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0028
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0027
6107 Cytochrome P450 3A7 CYP3A7 0.0026
4118 Cytochrome P450 3A5 CYP3A5 0.0025
153 Dopamine beta-hydroxylase DBH 0.0025
6144 Solute carrier family 22 member 2 SLC22A2 0.0024
833 Organic cation/carnitine transporter 1 SLC22A4 0.0024
6133 Sodium channel subunit beta-2 SCN2B 0.002
6134 Sodium channel subunit beta-3 SCN3B 0.002
6132 Sodium channel subunit beta-1 SCN1B 0.002
6135 Sodium channel subunit beta-4 SCN4B 0.002
6127 Carbonic anhydrase-related protein CA8 0.002
6129 Carbonic anhydrase-related protein 11 CA11 0.002
6128 Carbonic anhydrase-related protein 10 CA10 0.002
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.002
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.002
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.002
163 D(1B) dopamine receptor DRD5 0.0019
6024 Cytochrome P450 1A1 CYP1A1 0.0019
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0018
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0018
6130 Carbonic anhydrase 13 CA13 0.0018
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0018
432 D(4) dopamine receptor DRD4 0.0018
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0018
638 D(3) dopamine receptor DRD3 0.0017
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0017
6131 Carbonic anhydrase 14 CA14 0.0017
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0017
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0016
6122 Carbonic anhydrase 3 CA3 0.0016
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0015
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0015
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0015
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0015
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0015
756 Sex hormone-binding globulin SHBG 0.0015
3007 Carbonic anhydrase 12 CA12 0.0014
4205 Carbonic anhydrase 9 CA9 0.0014
6141 Sodium/bile acid cotransporter SLC10A1 0.0014
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0014
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0013
6126 Carbonic anhydrase 7 CA7 0.0013
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0013
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0013
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0012
1898 Cytochrome P450 1B1 CYP1B1 0.0012
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0011
6143 Solute carrier family 22 member 7 SLC22A7 0.0011
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0011
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0011
6020 Aldehyde oxidase AOX1 0.0011
592 Carbonic anhydrase 4 CA4 0.0011
295 Carbonic anhydrase 1 CA1 0.001
6142 Solute carrier family 22 member 8 SLC22A8 0.001
220 Sodium channel protein type 5 subunit alpha SCN5A 0.001
587 Serum albumin ALB 0.0009
4439 Ferredoxin reductase bphA4 0.0009
4486 Phenol 2-hydroxylase component B pheA2 0.0009
4477 Dihydrolipoyl dehydrogenase lpdV 0.0009
5077 Dihydrolipoyl dehydrogenase Not Available 0.0009
5117 Dihydrolipoyl dehydrogenase lpd 0.0009
5078 Amine oxidase, flavin-containing PSPTO1126 0.0009
5095 Putidaredoxin reductase camA 0.0009
5122 Mersacidin decarboxylase mrsD 0.0009
526 Thioredoxin reductase trxB 0.0009
3767 Thioredoxin reductase trxB 0.0009
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0009
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0009
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0009
5109 Outer membrane protein p64k or PM-6 m-6 0.0009
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0009
5115 FkbI fkbI 0.0009
3133 UDP-galactopyranose mutase glf 0.0009
5099 UDP-galactopyranose mutase glf 0.0009
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0009
5083 Cryptochrome DASH cry 0.0009
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0009
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0009
3763 5,10-methylenetetrahydrofolate reductase metF 0.0009
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0009
5094 5,10-methylenetetrahydrofolate reductase metF 0.0009
5081 L-aspartate oxidase nadB 0.0009
5111 Phenylacetone monooxygenase pamO 0.0009
1410 Oxidoreductase HSD17B6 0.0008
4725 Oxidoreductase Not Available 0.0008
5124 Oxidoreductase Not Available 0.0008
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0008
357 Carbonic anhydrase 2 CA2 0.0008
4440 NADH peroxidase npr 0.0008
3102 Flavohemoprotein hmp 0.0008
4969 Flavohemoprotein hmp 0.0008
327 Glutathione reductase gor 0.0007
5110 Glutathione reductase GR2 0.0007
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0007
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0007
3594 Deoxyribodipyrimidine photo-lyase phr 0.0007
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0007
5080 Deoxyribodipyrimidine photo-lyase phr 0.0007
5072 N,N-dimethylglycine oxidase dmg 0.0007
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0007
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0007
2470 Pyruvate oxidase pox5 0.0007
5073 Ferredoxin--NADP reductase petH 0.0007
5076 Ferredoxin--NADP reductase fpr 0.0007
5119 Ferredoxin--NADP reductase petH 0.0007
5121 Ferredoxin--NADP reductase fpr 0.0007
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0007
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0007
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0007
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0007
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0007
2268 Cholesterol oxidase choB 0.0007
2822 Cholesterol oxidase choA 0.0007
2526 NADPH-ferredoxin reductase fprA fprA 0.0007
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0007
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0007
126 D-lactate dehydrogenase dld 0.0007
3545 D-lactate dehydrogenase Not Available 0.0007
4510 D-lactate dehydrogenase ldhA 0.0007
605 Fumarate reductase flavoprotein subunit frdA 0.0007
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0007
3673 Fumarate reductase flavoprotein subunit fccA 0.0007
4912 Fumarate reductase flavoprotein subunit ifcA 0.0007
6549 Fumarate reductase flavoprotein subunit frdA 0.0007
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0007
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0007
2893 Glycine oxidase thiO 0.0007
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0006
2769 P-hydroxybenzoate hydroxylase pobA 0.0006
2809 P-hydroxybenzoate hydroxylase pobA 0.0006
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0006
2567 Thymidylate synthase thyX thyX 0.0006
2823 Trypanothione reductase TPR 0.0006
6645 D-amino-acid oxidase DAO 0.0006
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0006
2380 Monomeric sarcosine oxidase soxA 0.0006
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0005
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0005
714 Glutathione reductase, mitochondrial GSR 0.0005
4120 NADPH--cytochrome P450 reductase POR 0.0005
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0005
76 Nitric-oxide synthase, brain NOS1 0.0005
3947 Xanthine dehydrogenase/oxidase XDH 0.0004
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