DT-Web

DB07718 - 3-(4-HYDROXY-PHENYL)PYRUVIC ACID


Identification
Name 3-(4-HYDROXY-PHENYL)PYRUVIC ACID
Accession Number DB07718
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 180.1574
Groups experimental
Monoisotopic Weight 180.042258744
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prothrombin
Name Prothrombin
Gene Name F2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7337
Macrophage migration inhibitory factor
Name Macrophage migration inhibitory factor
Gene Name MIF
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5932
Prephenate dehydrogenase
Name Prephenate dehydrogenase
Gene Name tyrA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7642

Predictions


Id Partner name Gene Name Score
3099 Tyrosine phenol-lyase tpl 0.3261
6627 Tyrosine phenol-lyase tpl 0.3261
3176 Trypsin-1 PRSS1 0.1044
2369 Photoactive yellow protein pyp 0.0854
96 Histidine ammonia-lyase HAL 0.0853
6257 Histidine ammonia-lyase Not Available 0.0853
6536 Histidine ammonia-lyase hutH 0.0853
357 Carbonic anhydrase 2 CA2 0.0547
239 Coagulation factor X F10 0.0394
1074 Urokinase-type plasminogen activator PLAU 0.0362
369 Coagulation factor VII F7 0.0173
3119 Fimbrial protein pilE1 0.0168
6240 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 0.0122
2331 HTH-type transcriptional regulator qacR qacR 0.01
6461 HTH-type transcriptional regulator qacR qacR 0.01
6828 TetR family transcriptional repressor LfrR lfrR 0.0095
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0093
19 Coagulation factor VIII F8 0.0083
1757 Myeloperoxidase MPO 0.0083
798 Osteocalcin BGLAP 0.008
3831 Low-density lipoprotein receptor-related protein 1 LRP1 0.0075
3851 Serine protease hepsin HPN 0.0071
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0064
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0049
4757 Cytochrome P450 2C9 CYP2C9 0.0048
4165 P2Y purinoceptor 2 P2RY2 0.0047
5591 Complement component C8 gamma chain C8G 0.0046
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0046
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0046
4695 UPF0124 protein yfiH yfiH 0.0046
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0046
2300 Lysozyme E 0.0046
3633 Lysozyme R 0.0046
5597 Lysozyme 17 0.0046
5575 Short tail fiber protein 12 0.0046
5587 Iron(III)-binding periplasmic protein fbpA 0.0046
5600 Pyruvate decarboxylase pdc 0.0046
5582 Regulator of transcription; stringent starvation protein A sspA 0.0046
2838 Ribose-5-phosphate isomerase A rpiA 0.0046
2952 Ribose-5-phosphate isomerase A rpiA 0.0046
5595 Ribose-5-phosphate isomerase A rpiA 0.0046
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0046
5593 Transferase Not Available 0.0046
4238 50S ribosomal protein L4 rplD 0.0046
5578 50S ribosomal protein L4 rplD 0.0046
6173 50S ribosomal protein L4 rplD 0.0046
6219 50S ribosomal protein L4 rplD 0.0046
5060 Intron-associated endonuclease 1 ITEVIR 0.0046
5588 Cell division protein FtsY TM_0570 0.0046
5590 N utilization substance protein B homolog nusB 0.0046
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0046
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0046
4375 Glutamine synthetase 1 glnA1 0.0046
5581 Beta-fructosidase bfrA 0.0046
5580 Hexon protein PII 0.0046
5574 Invasin YPTB1668 0.0046
5006 RNASE4 protein RNASE4 0.004
4533 Glyoxalase family protein BC_1747 0.004
4992 Cytochrome c peroxidase Not Available 0.004
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.004
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.004
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.004
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.004
3132 Tryptophan synthase alpha chain trpA 0.004
6568 Tryptophan synthase alpha chain trpA 0.004
5328 Prostaglandin F synthase Tb11.02.2310 0.004
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.004
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.004
3729 Citrate synthase gltA 0.004
4575 Citrate synthase cit 0.004
4580 Citrate synthase gltA 0.004
2555 Pol polyprotein pol 0.004
3242 Pol polyprotein gag-pol 0.004
3471 Pol polyprotein gag-pro-pol 0.004
5256 Pol polyprotein pol 0.004
6469 Pol polyprotein gag-pol 0.004
6565 Pol polyprotein Not Available 0.004
400 Coagulation factor IX F9 0.0039
5461 Coagulation factor IX F9 0.0039
1547 Coagulation factor XI F11 0.0039
2654 Complement control protein C3L 0.0037
2149 Angiogenin ANG 0.0037
3583 6-phosphogluconolactonase pgl 0.0037
2603 Beta-lactamase II blm 0.0037
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0037
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0037
2521 Cell division protein ftsZ ftsZ 0.0037
3301 Cell division protein ftsZ ftsZ 0.0037
1959 Platelet factor 4 PF4 0.0035
3865 Serpin B6 SERPINB6 0.0035
1986 Ceruloplasmin CP 0.0035
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0035
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0035
2286 Isocitrate dehydrogenase [NADP] icd 0.0035
2302 Isocitrate dehydrogenase [NADP] icd 0.0035
2771 Isocitrate dehydrogenase [NADP] icd 0.0035
3486 Fumarate hydratase class II fumC 0.0035
2942 Sialidase nanH 0.0035
3546 Sialidase nedA 0.0035
1245 Vitamin K-dependent protein S PROS1 0.0035
4118 Cytochrome P450 3A5 CYP3A5 0.0035
430 Follicle-stimulating hormone receptor FSHR 0.0034
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0034
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0033
422 Vitamin K-dependent protein C PROC 0.0033
3842 Multiple coagulation factor deficiency protein 2 MCFD2 0.0033
3841 ERGIC-53 protein LMAN1 0.0033
3840 Asialoglycoprotein receptor 2 ASGR2 0.0033
1847 78 kDa glucose-regulated protein HSPA5 0.0033
1635 von Willebrand factor VWF 0.0033
1123 Eosinophil cationic protein RNASE3 0.0033
332 Beta-lactamase blaZ 0.0032
2478 Beta-lactamase ampC 0.0032
2613 Beta-lactamase ampC 0.0032
2635 Beta-lactamase ampC 0.0032
2700 Beta-lactamase penP 0.0032
5445 Beta-lactamase blaB 0.0032
6019 Beta-lactamase SHV-7 0.0032
6701 Beta-lactamase cphA 0.0032
5455 Arylsulfatase A ARSA 0.0032
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0032
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0032
2697 Uridine-cytidine kinase 2 UCK2 0.0032
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0032
857 Malate dehydrogenase, mitochondrial MDH2 0.0032
2452 Tryptophanyl-tRNA synthetase trpS 0.0032
3833 Plasma serine protease inhibitor SERPINA5 0.0031
4604 Liver carboxylesterase 1 CES1 0.0031
2072 Endothelial protein C receptor PROCR 0.0031
46 Coagulation factor V F5 0.0031
5579 Carboxypeptidase B CPB1 0.003
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0029
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0029
814 Ryanodine receptor 1 RYR1 0.0029
4512 Cytochrome P450 3A4 CYP3A4 0.0028
1516 Calnexin CANX 0.0028
411 Glycine N-methyltransferase GNMT 0.0028
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0027
2981 Phospholipase A2, membrane associated PLA2G2A 0.0026
2021 Thrombomodulin THBD 0.0026
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0025
128 Adenine phosphoribosyltransferase APRT 0.0025
3830 Calreticulin CALR 0.0023
3839 Phytanoyl-CoA dioxygenase, peroxisomal PHYH 0.0023
5682 Ribonuclease pancreatic RNASE1 0.0023
822 Aldose reductase AKR1B1 0.0023
267 Plasminogen activator inhibitor 1 SERPINE1 0.0023
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0023
723 Cytosolic phospholipase A2 PLA2G4A 0.0023
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0021
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0017
1588 Multidrug resistance protein 1 ABCB1 0.0016
604 Vitamin K-dependent protein Z PROZ 0.0014
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0014
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.001
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.001
3917 Methylenetetrahydrofolate reductase MTHFR 0.0009
6020 Aldehyde oxidase AOX1 0.0009
3947 Xanthine dehydrogenase/oxidase XDH 0.0008
5718 Cytochrome P450 2A6 CYP2A6 0.0006
6024 Cytochrome P450 1A1 CYP1A1 0.0006
6013 Cytochrome P450 2E1 CYP2E1 0.0006
4200 Cytochrome P450 1A2 CYP1A2 0.0005
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