DT-Web

DB07715 - 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE


Identification
Name 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE
Accession Number DB07715
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 270.2369
Groups experimental
Monoisotopic Weight 270.05282343
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Casein kinase II subunit alpha
Name Casein kinase II subunit alpha
Gene Name CSNK2A1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8081
Putative ketoacyl reductase
Name Putative ketoacyl reductase
Gene Name actIII
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.3555
(3R)-hydroxymyristoyl-acyl carrier protein dehydratase
Name (3R)-hydroxymyristoyl-acyl carrier protein dehydratase
Gene Name fabZ
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8544

Predictions


Id Partner name Gene Name Score
2889 Kallikrein-6 KLK6 0.0149
2947 Trypsin sprT 0.0149
4037 Hypothetical protein GPX1 0.0145
4297 Hypothetical protein SP_1951 0.0145
4521 Hypothetical protein BC_2969 0.0145
4540 Hypothetical protein TM_1070 0.0145
4555 Hypothetical protein MT1739 0.0145
4569 Hypothetical protein mshD 0.0145
4578 Hypothetical protein PA3270 0.0145
4747 Hypothetical protein PA3967 0.0145
5177 Hypothetical protein TM_0096 0.0145
5194 Hypothetical protein PA1204 0.0145
5240 Hypothetical protein Rv2991 0.0145
5370 Hypothetical protein TM_1158 0.0145
5710 Hypothetical protein Tb927.5.1360 0.0145
4527 Putative hydrolase ycdX ycdX 0.0144
4538 Hypothetical protein VC1899 VC_1899 0.0144
2501 Protein ygbM ygbM 0.0144
4545 Molybdopterin-converting factor subunit 2 moaE 0.0144
4514 Citrate lyase beta subunit-like protein citE 0.0144
4781 Citrate lyase beta subunit-like protein DR_1240 0.0144
4536 Transcriptional regulator, IclR family TM_0065 0.0144
4522 Arginine N-succinyltransferase subunit alpha astA 0.0144
4106 Guanylate kinase GUK1 0.0144
4516 Guanylate kinase gmk 0.0144
4529 Oxalate decarboxylase oxdC oxdC 0.0144
4547 Iron binding protein FbpA fbpA 0.0144
658 Para-aminobenzoate synthase component 1 pabB 0.0144
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0144
4524 Mannose-6-phosphate isomerase yvyI 0.0144
4548 Gyrase B gyrB 0.0144
4546 Aminotransferase, putative TM_1131 0.0144
4515 Peripheral plasma membrane protein CASK CASK 0.0144
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0144
6837 Serine/threonine-protein kinase 17B STK17B 0.0142
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0142
76 Nitric-oxide synthase, brain NOS1 0.0135
4814 Copper transport protein ATOX1 ATOX1 0.013
3211 3,2-trans-enoyl-CoA isomerase, mitochondrial DCI 0.013
3011 Suppressor of tumorigenicity protein 14 ST14 0.013
2929 (S)-2-haloacid dehalogenase dhlB 0.0126
2995 (S)-2-haloacid dehalogenase Not Available 0.0126
4533 Glyoxalase family protein BC_1747 0.0126
3237 Beta-lactamase OXA-2 bla 0.0126
4542 Glutaminase 1 glsA1 0.0126
4544 Glutaminase 1 glsA1 0.0126
56 Delta-aminolevulinic acid dehydratase ALAD 0.0126
2356 Delta-aminolevulinic acid dehydratase hemB 0.0126
3613 Delta-aminolevulinic acid dehydratase hemB 0.0126
3674 Delta-aminolevulinic acid dehydratase hemB 0.0126
4528 Phenazine biosynthesis protein PhzD phzD1 0.0126
4517 Probable butyrate kinase 2 buk2 0.0126
3759 Glutathione S-transferase gst 0.0126
4541 Glutathione S-transferase GST 0.0126
3261 Signal recognition particle protein ffh 0.0126
4496 C-terminal-binding protein 1 CTBP1 0.0126
4532 Gephyrin GPHN 0.0126
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0124
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0122
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0122
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0122
5332 MtdA bifunctional protein mtdA 0.0122
4403 Protein iolS iolS 0.0122
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0122
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0122
3778 NAD(P) transhydrogenase subunit beta pntB 0.0122
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0122
5322 Oxidoreductase ydhF ydhF 0.0122
5330 General stress protein 69 yhdN 0.0122
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0122
3467 Methylglyoxal synthase mgsA 0.0116
2775 Dihydroorotate dehydrogenase pyrD 0.0116
3583 6-phosphogluconolactonase pgl 0.0116
2230 Catalase CAT 0.0116
3249 Catalase katA 0.0116
3625 Catalase katA 0.0116
4539 Catalase katA 0.0116
4941 Catalase katB 0.0116
6599 HTH-type transcriptional regulator ttgR ttgR 0.0114
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0109
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0109
2599 Tyrosine-protein kinase HCK HCK 0.0108
989 L-xylulose reductase DCXR 0.0107
4582 Putative pteridine reductase 2 ptr2 0.0106
3446 NADP-dependent alcohol dehydrogenase adh 0.0106
5073 Ferredoxin--NADP reductase petH 0.0106
5076 Ferredoxin--NADP reductase fpr 0.0106
5119 Ferredoxin--NADP reductase petH 0.0106
5121 Ferredoxin--NADP reductase fpr 0.0106
2636 Shikimate dehydrogenase aroE 0.0106
3515 Shikimate dehydrogenase aroE 0.0106
5328 Prostaglandin F synthase Tb11.02.2310 0.0106
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0106
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0106
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0106
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0106
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0106
729 GDP-L-fucose synthetase TSTA3 0.0106
3463 GDP-L-fucose synthetase fcl 0.0106
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0106
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0106
2286 Isocitrate dehydrogenase [NADP] icd 0.0106
2302 Isocitrate dehydrogenase [NADP] icd 0.0106
2771 Isocitrate dehydrogenase [NADP] icd 0.0106
2688 Peptide deformylase def 0.0105
2708 Peptide deformylase def 0.0105
3004 Peptide deformylase def 0.0105
4337 Peptide deformylase def 0.0105
4338 Peptide deformylase def 0.0105
5368 Peptide deformylase def 0.0105
5371 Peptide deformylase def 0.0105
6375 Peptide deformylase def 0.0105
6378 Peptide deformylase def 0.0105
6379 Peptide deformylase def 0.0105
6776 Peptide deformylase def 0.0105
6900 Peptide deformylase def 0.0105
4534 Cytohesin-2 CYTH2 0.0105
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0103
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0103
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0103
2548 Subtilisin Carlsberg apr 0.0101
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0099
2886 Trypsin-3 PRSS3 0.0098
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0098
6297 Prostaglandin reductase 1 PTGR1 0.0098
3062 Aspartate-semialdehyde dehydrogenase asd 0.0098
2675 Pteridine reductase 1 PTR1 0.0093
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0093
1124 Sepiapterin reductase SPR 0.0092
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0092
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0091
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0089
666 NADP-dependent malic enzyme ME1 0.0089
646 Malate dehydrogenase, cytoplasmic MDH1 0.0087
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0087
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0086
2159 Quinone oxidoreductase CRYZ 0.0086
760 Fibroblast growth factor 1 FGF1 0.0085
810 Heme oxygenase 1 HMOX1 0.0085
3391 Heme oxygenase 1 pbsA1 0.0085
3027 Streptavidin Not Available 0.0084
500 Monocarboxylate transporter 4 SLC16A3 0.0081
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.008
489 Monocarboxylate transporter 2 SLC16A7 0.0079
357 Carbonic anhydrase 2 CA2 0.0078
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0077
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0076
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0076
654 Flavin reductase BLVRB 0.0075
1074 Urokinase-type plasminogen activator PLAU 0.0073
5682 Ribonuclease pancreatic RNASE1 0.0072
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0071
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0069
444 Alcohol dehydrogenase 1B ADH1B 0.0068
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0066
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0066
373 Transthyretin TTR 0.0065
822 Aldose reductase AKR1B1 0.0061
738 Monocarboxylate transporter 1 SLC16A1 0.006
3176 Trypsin-1 PRSS1 0.0059
6024 Cytochrome P450 1A1 CYP1A1 0.0059
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0057
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0057
365 Dihydrofolate reductase DHFR 0.0057
2381 Dihydrofolate reductase DFR1 0.0057
2833 Dihydrofolate reductase Not Available 0.0057
2931 Dihydrofolate reductase folA 0.0057
3544 Dihydrofolate reductase folA 0.0057
3682 Dihydrofolate reductase folA 0.0057
6642 Dihydrofolate reductase folA 0.0057
6756 Dihydrofolate reductase dfrA 0.0057
4120 NADPH--cytochrome P450 reductase POR 0.0055
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0053
1898 Cytochrome P450 1B1 CYP1B1 0.0049
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0049
997 Protein kinase C beta type PRKCB 0.0047
2408 Tyrosine-protein kinase SYK SYK 0.0047
290 Prostaglandin G/H synthase 2 PTGS2 0.0046
862 Multidrug resistance-associated protein 1 ABCC1 0.0045
20 Prostaglandin G/H synthase 1 PTGS1 0.0043
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0042
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0042
6131 Carbonic anhydrase 14 CA14 0.0041
1970 Protein kinase C alpha type PRKCA 0.0041
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0041
6122 Carbonic anhydrase 3 CA3 0.0041
634 Squalene monooxygenase SQLE 0.0037
7196 Squalene monooxygenase ERG1 0.0037
4205 Carbonic anhydrase 9 CA9 0.0035
3007 Carbonic anhydrase 12 CA12 0.0035
4924 Cytochrome P450 2C8 CYP2C8 0.0035
4200 Cytochrome P450 1A2 CYP1A2 0.0034
6126 Carbonic anhydrase 7 CA7 0.0033
1588 Multidrug resistance protein 1 ABCB1 0.0032
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0031
4512 Cytochrome P450 3A4 CYP3A4 0.0029
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0029
5641 Rod shape-determining protein MreB TM_0588 0.0029
3794 Osmolarity sensor protein envZ envZ 0.0029
5644 Sensor protein phoQ phoQ 0.0029
5643 General secretion pathway protein E epsE 0.0029
5645 DNA topoisomerase 4 subunit B parE 0.0029
6227 DNA topoisomerase 4 subunit B parE 0.0029
5649 Potassium-transporting ATPase B chain kdpB 0.0029
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0029
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0029
5642 Chaperone clpB clpB 0.0029
2282 Protein recA recA 0.0025
2315 Protein recA recA 0.0025
2332 Protein recA recA 0.0025
5263 Protein recA recA 0.0025
740 Argininosuccinate synthase ASS1 0.0025
865 Argininosuccinate synthase ASS1 0.0025
2680 Argininosuccinate synthase argG 0.0025
3194 Argininosuccinate synthase argG 0.0025
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0025
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0025
4751 Mitogen-activated protein kinase 12 MAPK12 0.0025
5646 Galactokinase GALK1 0.0025
2852 DNA mismatch repair protein mutL mutL 0.0025
5265 FtsH ftsH 0.0025
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0025
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0025
5302 TrwB trwB 0.0025
2397 Dihydroxyacetone kinase dhaK 0.0025
592 Carbonic anhydrase 4 CA4 0.0025
295 Carbonic anhydrase 1 CA1 0.0025
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0023
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0023
3231 Death-associated protein kinase 1 DAPK1 0.0023
5312 Kinesin-like protein KIF1A KIF1A 0.0023
2892 Acetylglutamate kinase argB 0.0022
3550 Acetylglutamate kinase argB 0.0022
2371 Pantothenate kinase coaA 0.0022
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0022
2615 Chemotaxis protein cheA cheA 0.0022
825 Arsenical pump-driving ATPase ASNA1 0.0022
3435 Arsenical pump-driving ATPase arsA 0.0022
1881 Hexokinase-1 HK1 0.0022
1024 Solute carrier family 22 member 11 SLC22A11 0.0022
2727 S-adenosylmethionine synthetase metK 0.0021
887 DNA gyrase subunit B gyrB 0.0021
4150 DNA gyrase subunit B gyrB 0.0021
6225 DNA gyrase subunit B gyrB 0.0021
936 Ephrin type-A receptor 2 EPHA2 0.0021
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.002
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.002
958 Insulin-like growth factor 1 receptor IGF1R 0.0019
2251 Thymidylate kinase tmk 0.0018
2254 Thymidylate kinase DTYMK 0.0018
3522 Thymidylate kinase tmk 0.0018
1729 Solute carrier family 22 member 6 SLC22A6 0.0018
6013 Cytochrome P450 2E1 CYP2E1 0.0018
3822 Actin, alpha skeletal muscle ACTA1 0.0017
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0017
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0017
1836 Mitogen-activated protein kinase 10 MAPK10 0.0017
4192 DNA topoisomerase 2-beta TOP2B 0.0016
207 Glutathione synthetase GSS 0.0016
5269 Glutathione synthetase gshB 0.0016
1721 Glycogen synthase kinase-3 beta GSK3B 0.0016
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