DT-Web

DB07288 - N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide


Identification
Name N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
Accession Number DB07288
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 337.803
Groups experimental
Monoisotopic Weight 337.098189856
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Vascular endothelial growth factor receptor 1
Name Vascular endothelial growth factor receptor 1
Gene Name FLT1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.3913

Predictions


Id Partner name Gene Name Score
26 Vascular endothelial growth factor receptor 3 FLT4 0.0801
407 Vascular endothelial growth factor receptor 2 KDR 0.0627
228 Beta platelet-derived growth factor receptor PDGFRB 0.0471
504 Mast/stem cell growth factor receptor KIT 0.0447
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0407
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.035
1588 Multidrug resistance protein 1 ABCB1 0.0291
165 FL cytokine receptor FLT3 0.0287
4512 Cytochrome P450 3A4 CYP3A4 0.0256
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0253
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0229
4118 Cytochrome P450 3A5 CYP3A5 0.0215
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0208
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0204
4200 Cytochrome P450 1A2 CYP1A2 0.0194
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0193
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0193
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0182
6016 Cytochrome P450 2C19 CYP2C19 0.0179
3856 Fibroblast growth factor receptor 3 FGFR3 0.0177
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0166
5798 Mitogen-activated protein kinase 11 MAPK11 0.0153
2164 Multidrug resistance-associated protein 4 ABCC4 0.0148
4924 Cytochrome P450 2C8 CYP2C8 0.0144
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0131
760 Fibroblast growth factor 1 FGF1 0.0127
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0125
6107 Cytochrome P450 3A7 CYP3A7 0.0117
5787 Angiopoietin-1 receptor TEK 0.011
936 Ephrin type-A receptor 2 EPHA2 0.0109
1618 High affinity nerve growth factor receptor NTRK1 0.0102
823 Fibroblast growth factor receptor 2 FGFR2 0.01
4119 Cytochrome P450 2D6 CYP2D6 0.0092
6030 Cytochrome P450 2B6 CYP2B6 0.009
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0081
4757 Cytochrome P450 2C9 CYP2C9 0.0076
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