DT-Web

DB07202 - 6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE


Identification
Name 6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE
Accession Number DB07202
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 336.772
Groups experimental
Monoisotopic Weight 336.066555377
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Macrophage colony-stimulating factor 1 receptor
Name Macrophage colony-stimulating factor 1 receptor
Gene Name CSF1R
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8501

Predictions


Id Partner name Gene Name Score
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0351
228 Beta platelet-derived growth factor receptor PDGFRB 0.0318
504 Mast/stem cell growth factor receptor KIT 0.0306
165 FL cytokine receptor FLT3 0.0222
26 Vascular endothelial growth factor receptor 3 FLT4 0.0218
32 Vascular endothelial growth factor receptor 1 FLT1 0.0212
407 Vascular endothelial growth factor receptor 2 KDR 0.0175
1864 RET proto-oncogene RET 0.017
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.017
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0169
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0169
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0169
6107 Cytochrome P450 3A7 CYP3A7 0.015
4118 Cytochrome P450 3A5 CYP3A5 0.0143
1618 High affinity nerve growth factor receptor NTRK1 0.0137
1588 Multidrug resistance protein 1 ABCB1 0.0131
2164 Multidrug resistance-associated protein 4 ABCC4 0.0117
4512 Cytochrome P450 3A4 CYP3A4 0.0115
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0109
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0103
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0076
6144 Solute carrier family 22 member 2 SLC22A2 0.0067
6145 Solute carrier family 22 member 1 SLC22A1 0.0066
20 Prostaglandin G/H synthase 1 PTGS1 0.0064
587 Serum albumin ALB 0.006
6016 Cytochrome P450 2C19 CYP2C19 0.0053
4200 Cytochrome P450 1A2 CYP1A2 0.0052
4757 Cytochrome P450 2C9 CYP2C9 0.005
4119 Cytochrome P450 2D6 CYP2D6 0.0049
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