DT-Web

DB06933 - N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide


Identification
Name N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide
Accession Number DB06933
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 432.538
Groups experimental
Monoisotopic Weight 432.161996722
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Mitogen-activated protein kinase 10
Name Mitogen-activated protein kinase 10
Gene Name MAPK10
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.679

Predictions


Id Partner name Gene Name Score
6653 cDNA FLJ42801 fis, clone BRCAN2001223, highly similar to Mitogen-activated protein kinase 10 (EC 2.7.11.24) MAPK10 0.103
1176 Mitogen-activated protein kinase 1 MAPK1 0.0493
6293 Dual specificity protein kinase TTK TTK 0.0441
6292 Mitogen-activated protein kinase 8 MAPK8 0.0348
6291 C-jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 0.0334
5643 General secretion pathway protein E epsE 0.0038
5641 Rod shape-determining protein MreB TM_0588 0.0038
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0038
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
3794 Osmolarity sensor protein envZ envZ 0.0038
5644 Sensor protein phoQ phoQ 0.0038
5642 Chaperone clpB clpB 0.0038
5645 DNA topoisomerase 4 subunit B parE 0.0038
6227 DNA topoisomerase 4 subunit B parE 0.0038
5649 Potassium-transporting ATPase B chain kdpB 0.0038
4751 Mitogen-activated protein kinase 12 MAPK12 0.0034
5646 Galactokinase GALK1 0.0033
740 Argininosuccinate synthase ASS1 0.0033
865 Argininosuccinate synthase ASS1 0.0033
2680 Argininosuccinate synthase argG 0.0033
3194 Argininosuccinate synthase argG 0.0033
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0033
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0033
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0033
2282 Protein recA recA 0.0033
2315 Protein recA recA 0.0033
2332 Protein recA recA 0.0033
5263 Protein recA recA 0.0033
2397 Dihydroxyacetone kinase dhaK 0.0033
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0033
5302 TrwB trwB 0.0033
2852 DNA mismatch repair protein mutL mutL 0.0033
5265 FtsH ftsH 0.0033
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0031
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0031
3231 Death-associated protein kinase 1 DAPK1 0.0031
5312 Kinesin-like protein KIF1A KIF1A 0.0031
2892 Acetylglutamate kinase argB 0.0029
3550 Acetylglutamate kinase argB 0.0029
2371 Pantothenate kinase coaA 0.0029
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0029
825 Arsenical pump-driving ATPase ASNA1 0.0029
3435 Arsenical pump-driving ATPase arsA 0.0029
2615 Chemotaxis protein cheA cheA 0.0029
1881 Hexokinase-1 HK1 0.0029
2727 S-adenosylmethionine synthetase metK 0.0028
887 DNA gyrase subunit B gyrB 0.0027
4150 DNA gyrase subunit B gyrB 0.0027
6225 DNA gyrase subunit B gyrB 0.0027
936 Ephrin type-A receptor 2 EPHA2 0.0027
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0027
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0026
958 Insulin-like growth factor 1 receptor IGF1R 0.0025
2251 Thymidylate kinase tmk 0.0024
2254 Thymidylate kinase DTYMK 0.0024
3522 Thymidylate kinase tmk 0.0024
3822 Actin, alpha skeletal muscle ACTA1 0.0023
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0022
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0022
4192 DNA topoisomerase 2-beta TOP2B 0.0021
207 Glutathione synthetase GSS 0.0021
5269 Glutathione synthetase gshB 0.0021
1721 Glycogen synthase kinase-3 beta GSK3B 0.0021
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0021
2236 Casein kinase II subunit alpha CSNK2A1 0.002
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