DT-Web

DB06842 - (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one


Identification
Name (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one
Accession Number DB06842
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 278.3468
Groups experimental
Monoisotopic Weight 278.16304258
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


cAMP-specific 3',5'-cyclic phosphodiesterase 4A
Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A
Gene Name PDE4A
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Gene Name PDE4D
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.4143
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.192
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0632
779 High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A PDE7A 0.0561
1178 Adenosine A2a receptor ADORA2A 0.0498
16 Adenosine A1 receptor ADORA1 0.0489
691 cAMP-specific 3',5'-cyclic phosphodiesterase 7B PDE7B 0.0451
268 Adenosine A2b receptor ADORA2B 0.0442
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0391
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.038
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.037
6216 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A PDE8A 0.0358
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0326
6217 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B PDE8B 0.0225
4122 Histone deacetylase 2 HDAC2 0.0193
1792 Tissue-type plasminogen activator PLAT 0.0182
527 Prostacyclin receptor PTGIR 0.0164
1830 5'-nucleotidase NT5E 0.0162
3957 Adenosine deaminase ADA 0.0156
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0151
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.015
5360 High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A 0.0149
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0147
4200 Cytochrome P450 1A2 CYP1A2 0.0146
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0144
2256 cGMP-inhibited 3',5'-cyclic phosphodiesterase B PDE3B 0.0122
6143 Solute carrier family 22 member 7 SLC22A7 0.0121
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0119
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.011
6136 Multidrug resistance-associated protein 5 ABCC5 0.0104
492 Histamine H1 receptor HRH1 0.0096
4512 Cytochrome P450 3A4 CYP3A4 0.0093
2164 Multidrug resistance-associated protein 4 ABCC4 0.0087
1588 Multidrug resistance protein 1 ABCB1 0.0059
851 5'-AMP-activated protein kinase subunit beta-2 PRKAB2 0.0056
388 AMP deaminase 1 AMPD1 0.0056
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0055
4198 Fructose-1,6-bisphosphatase 1 FBP1 0.005
1291 cAMP response element-binding protein CREB1 0.0049
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0049
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0049
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0049
297 Adenylate cyclase type 1 ADCY1 0.0049
128 Adenine phosphoribosyltransferase APRT 0.0047
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.0047
10 Glycogen phosphorylase, liver form PYGL 0.0046
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0045
6021 Adenosine kinase ADK 0.0045
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0043
1898 Cytochrome P450 1B1 CYP1B1 0.0035
6024 Cytochrome P450 1A1 CYP1A1 0.0028
6013 Cytochrome P450 2E1 CYP2E1 0.0027
4924 Cytochrome P450 2C8 CYP2C8 0.0025
4757 Cytochrome P450 2C9 CYP2C9 0.0023
4119 Cytochrome P450 2D6 CYP2D6 0.0023
↑