DT-Web

DB04467 - Pyridoxyl-Alanine-5-Phosphate


Identification
Name Pyridoxyl-Alanine-5-Phosphate
Accession Number DB04467 (EXPT02529, EXPT02532, EXPT02635)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 320.2356
Groups experimental
Monoisotopic Weight 320.07733742
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


L-cysteine/cystine lyase C-DES
Name L-cysteine/cystine lyase C-DES
Gene Name c-des
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.5967
Alanine racemase
Name Alanine racemase
Gene Name alr
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2563
Aspartate aminotransferase
Name Aspartate aminotransferase
Gene Name aspC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.3764

Predictions


Id Partner name Gene Name Score
2671 Aspartate aminotransferase aspC 1.3764
5490 Aspartate aminotransferase Not Available 1.3764
894 Alanine racemase alr 1.2563
2749 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase arnB 0.1218
3204 Thiosulfate sulfurtransferase glpE glpE 0.1089
4801 Diphtheria toxin repressor dtxR 0.1088
4803 3-mercaptopyruvate sulfurtransferase sseA 0.1087
3527 Thiosulfate sulfurtransferase rhdA 0.1087
4806 Thiosulfate sulfurtransferase TTHA1028 0.1087
6965 Thiosulfate sulfurtransferase TST 0.1087
2537 Aromatic-amino-acid aminotransferase tyrB 0.1082
5358 Aminodeoxychorismate lyase pabC 0.1076
4134 Mercaptopyruvate sulfurtransferase MST 0.0946
3274 Hydroxylamine reductase hcp 0.0946
4804 Hydroxylamine reductase hcp 0.0946
2748 Cysteine desulfurase sufS 0.0825
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0817
4836 Ferredoxin-dependent glutamate synthase 2 gltS 0.059
4835 CarC carC 0.059
4584 Aminotransferase Not Available 0.0583
3617 Non-heme chloroperoxidase cpo 0.0538
5426 Non-heme chloroperoxidase cpo 0.0538
3526 Pseudomonalisin pcp 0.0538
4037 Hypothetical protein GPX1 0.0469
4297 Hypothetical protein SP_1951 0.0469
4521 Hypothetical protein BC_2969 0.0469
4540 Hypothetical protein TM_1070 0.0469
4555 Hypothetical protein MT1739 0.0469
4569 Hypothetical protein mshD 0.0469
4578 Hypothetical protein PA3270 0.0469
4747 Hypothetical protein PA3967 0.0469
5177 Hypothetical protein TM_0096 0.0469
5194 Hypothetical protein PA1204 0.0469
5240 Hypothetical protein Rv2991 0.0469
5370 Hypothetical protein TM_1158 0.0469
5710 Hypothetical protein Tb927.5.1360 0.0469
4532 Gephyrin GPHN 0.0468
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0387
2744 D-alanine aminotransferase dat 0.0323
2183 Fatty acid-binding protein, adipocyte FABP4 0.0322
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0322
2823 Trypanothione reductase TPR 0.0304
5353 Glutamate decarboxylase alpha gadA 0.0286
2746 4-aminobutyrate aminotransferase gabT 0.0281
2842 Glutamate-1-semialdehyde 2,1-aminomutase hemL 0.0281
2546 Histidinol-phosphate aminotransferase hisC 0.0259
2698 Histidinol-phosphate aminotransferase hisC 0.0259
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0232
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0218
5492 Cystathionine gamma-synthase metB 0.0185
5491 Methionine gamma-lyase mdeA 0.0185
763 Tyrosine aminotransferase TAT 0.0185
5493 Tyrosine aminotransferase Not Available 0.0185
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.018
4819 Hydrolase Not Available 0.017
5249 Hydrolase Not Available 0.017
5436 Hydrolase Not Available 0.017
3122 D-hydantoinase Not Available 0.017
3145 D-hydantoinase hyuA 0.017
3168 Beta-lactamase OXA-1 bla 0.017
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.017
4823 L-allo-threonine aldolase TM_1744 0.0148
3292 Alanine racemase, catabolic dadX 0.0148
3237 Beta-lactamase OXA-2 bla 0.0148
4264 Alpha-L-fucosidase, putative TM_0306 0.0148
3281 Isoaspartyl dipeptidase iadA 0.0148
2758 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase bioA 0.0147
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0136
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0136
4549 Endonuclease III HP_0602 0.0129
2646 Dihydroorotase pyrC 0.0129
2717 Folylpolyglutamate synthase fgs 0.0123
2340 Beta-lactamase PSE-2 bla 0.0116
2796 Parathion hydrolase opd 0.0115
6539 Parathion hydrolase opd 0.0115
449 Ornithine decarboxylase ODC1 0.0113
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0109
349 Serine--pyruvate aminotransferase AGXT 0.0105
1024 Solute carrier family 22 member 11 SLC22A11 0.01
6143 Solute carrier family 22 member 7 SLC22A7 0.0097
6142 Solute carrier family 22 member 8 SLC22A8 0.0088
1152 Glycogen phosphorylase, muscle form PYGM 0.0083
1729 Solute carrier family 22 member 6 SLC22A6 0.008
2240 Cell division protein kinase 2 CDK2 0.0064
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