DT-Web

DB04282 - 2-Deoxy-2fluoro-Glucose


Identification
Name 2-Deoxy-2fluoro-Glucose
Accession Number DB04282 (EXPT01525)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 182.1469
Groups experimental
Monoisotopic Weight 182.059051667
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cellulase B precursor
Name Cellulase B precursor
Gene Name celB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5878
Beta-glucosidase A
Name Beta-glucosidase A
Gene Name bglA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7757
Lactase-phlorizin hydrolase
Name Lactase-phlorizin hydrolase
Gene Name LCT
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2344
Exoglucanase/xylanase [Includes: Exoglucanase
Name Exoglucanase/xylanase [Includes: Exoglucanase
Gene Name cex
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4182

Predictions


Id Partner name Gene Name Score
3298 Beta-glucosidase A bglA 1.7757
4680 Amicyanin mauC 0.1234
4681 Aminopeptidase Not Available 0.1136
4272 POSSIBLE CELLULASE CELA1 celA1 0.108
24 Thymidylate synthase TMP1 0.0763
359 Thymidylate synthase TYMS 0.0763
2626 Thymidylate synthase thyA 0.0763
2729 Thymidylate synthase thyA 0.0763
5352 Thymidylate synthase THYA 0.0763
6614 Lactase-like protein LCTL 0.0726
4292 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase lpxA 0.0566
3076 Antigen 85-C fbpC 0.0565
5247 Endo-1,4-beta-xylanase Not Available 0.0479
5248 Endo-1,4-beta-xylanase xlnA 0.0479
5250 Endo-1,4-beta-xylanase xyl 0.0479
4669 Endo-1,4-beta-xylanase A xynA 0.0479
4715 Endo-1,4-beta-xylanase A xlnA 0.0479
5560 Endo-1,4-beta-xylanase A xynA 0.0479
1152 Glycogen phosphorylase, muscle form PYGM 0.0454
4819 Hydrolase Not Available 0.0443
5249 Hydrolase Not Available 0.0443
5436 Hydrolase Not Available 0.0443
3365 Beta-amylase spoII 0.0417
4830 Aldose 1-epimerase galM 0.0417
5245 Endo-beta-1,4-xylanase Not Available 0.0416
5246 Xylanase Y BH2105 0.0415
2430 Chondroitinase B cslB 0.038
4808 Endoxylanase xynC 0.0362
5023 Glycoside hydrolase Not Available 0.0362
5024 Glycoside hydrolase Not Available 0.0362
2581 Chondroitinase AC cslA 0.0287
193 Beta-1 adrenergic receptor ADRB1 0.0226
1184 Interferon beta IFNB1 0.0152
2245 Xylose isomerase xylA 0.0147
2253 Xylose isomerase xylA 0.0147
2260 Xylose isomerase xylA 0.0147
2431 Xylose isomerase xylA 0.0147
3689 Endoglucanase A celA 0.0135
5411 Slt-IIvB stxB2e 0.0134
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0134
5563 Galectin-2 LGALS2 0.0134
5046 Ecotin eco 0.0134
1875 Pulmonary surfactant-associated protein D SFTPD 0.0134
5553 Endoglucanase E1 Acel_0614 0.0134
3009 Beta-glucanase Not Available 0.0134
5559 Neopullulanase nplT 0.0134
5562 Hexokinase Not Available 0.0134
4670 Cellulase B celB 0.0134
3793 Aspartate ammonia-lyase aspA 0.0134
5554 D-galactose-binding periplasmic protein mglB 0.0134
3741 D-galactose-binding periplasmic protein precursor mglB 0.0134
5568 Endoglucanase C307 celC307 0.0134
4671 Endoglucanase C cenC 0.0134
5569 Endo-1,4-beta glucanase EngF engF 0.0134
4668 Laminarinase TM_0024 0.0134
5570 Endoglucanase E-4 celD 0.0134
3744 Endoglucanase SS precursor celS 0.0134
4667 BH0236 protein BH0236 0.0134
4666 Fucose-binding lectin PA-IIL lecB 0.0132
2372 Bifunctional tail protein 9 0.0132
1503 Galectin-7 LGALS7 0.0117
4509 Acetoin(diacetyl) reductase budC 0.0117
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0117
4622 Amylase Not Available 0.0117
5416 Coat protein VP1 Not Available 0.0117
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0117
5498 Maltoporin lamB 0.0117
5561 Maltoporin lamB 0.0117
5176 YtnJ moxC 0.0117
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0117
2705 Dimethyl sulfoxide reductase dmsA 0.0117
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0108
3547 Enterotoxin type B entB 0.0108
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0108
2541 Neopullulanase 1 tvaI 0.0108
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0108
4811 Amylosucrase ams 0.0108
2606 Neopullulanase 2 tvaII 0.0108
2531 Alpha-amylase amyE 0.0108
2948 Alpha-amylase amy 0.0108
3169 Alpha-amylase Not Available 0.0108
3091 Maltodextrin phosphorylase malP 0.0108
2324 Botulinum neurotoxin type B botB 0.0108
3225 Shiga toxin B-chain stxB 0.0102
2826 Glucose--fructose oxidoreductase gfo 0.0102
1881 Hexokinase-1 HK1 0.0102
1675 Glucokinase GCK 0.0097
4662 Glucokinase glk 0.0097
3030 Salivary alpha-amylase AMY1A 0.0097
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0097
2508 Cyclomaltodextrin glucanotransferase cgt 0.0097
2523 Cyclomaltodextrin glucanotransferase cgt 0.0097
3207 Cyclomaltodextrin glucanotransferase amyA 0.0097
3668 Maltose-binding periplasmic protein precursor malE 0.0094
2802 Endoglucanase G celCCG 0.0094
2570 Tetanus toxin tetX 0.0094
4692 A/G-specific adenine glycosylase mutY 0.0093
2440 Endoglucanase F celCCF 0.0088
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0085
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0085
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0085
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0085
2252 Endoglucanase 5A cel5A 0.0082
3839 Phytanoyl-CoA dioxygenase, peroxisomal PHYH 0.008
2723 Cholera enterotoxin subunit B ctxB 0.0079
3962 Egl nine homolog 3 EGLN3 0.0077
3948 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 ALKBH2 0.0077
3956 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 ALKBH3 0.0077
3946 Hypothetical protein DKFZp686H15154 OGFOD2 0.0077
189 Solute carrier family 23 member 1 SLC23A1 0.0077
3966 Putative HIF-prolyl hydroxylase PH-4 P4HTM 0.0077
3954 Egl nine homolog 2 EGLN2 0.0077
3953 2-oxoglutarate and iron-dependent oxygenase domain containing 1 OGFOD1 0.0077
3935 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 PLOD2 0.0077
3958 Jumonji/ARID domain-containing protein 1D KDM5D 0.0077
3943 Peptidyl-glycine alpha-amidating monooxygenase PAM 0.0076
3960 Egl nine homolog 1 EGLN1 0.0076
10 Glycogen phosphorylase, liver form PYGL 0.0076
2427 Ferrichrome-iron receptor fhuA 0.0075
4513 Pancreatic alpha-amylase AMY2A 0.0075
2485 Hyaluronate lyase SP_0314 0.0068
3172 Hyaluronate lyase hylB 0.0068
3940 Gamma-butyrobetaine dioxygenase BBOX1 0.0063
3964 Trimethyllysine dioxygenase, mitochondrial TMLHE 0.0063
3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 PLOD3 0.0063
97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 0.0063
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.0057
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.0057
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.0057
153 Dopamine beta-hydroxylase DBH 0.0054
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0054
20 Prostaglandin G/H synthase 1 PTGS1 0.0049
4878 Glycoprotein hormones alpha chain CGA 0.0041
1072 Granzyme B GZMB 0.0041
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0041
4877 Beta-mannanase man 0.0041
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0041
4889 Ig epsilon chain C region IGHE 0.0041
4850 Beta-2-glycoprotein 1 APOH 0.0041
4880 Membrane cofactor protein CD46 0.0041
1354 Beta-glucuronidase GUSB 0.0041
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0041
4856 CD209 antigen CD209 0.0041
757 Fusion glycoprotein F0 F 0.0041
4875 Fusion glycoprotein F0 F 0.0041
4189 Alpha-galactosidase A GLA 0.0041
4869 Major capsid protein A430L 0.0041
4852 Reticulon-4 receptor RTN4R 0.0041
442 Envelope glycoprotein gp41 0.0041
4859 Envelope glycoprotein env 0.0041
4845 ADAM 33 ADAM33 0.0041
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0041
4721 Beta-1,4-mannanase manA 0.0041
3352 Structural polyprotein Not Available 0.0041
3628 Structural polyprotein Not Available 0.0041
4892 Structural polyprotein Not Available 0.0041
4861 Interleukin-6 receptor alpha chain IL6R 0.0036
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0036
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0036
793 T-cell surface antigen CD2 CD2 0.0036
3837 Cytokine receptor common beta chain CSF2RB 0.0036
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0035
6858 Inactive carboxylesterase 4 CES1P1 0.0035
1379 Interleukin-12 subunit beta IL12B 0.0035
4890 Hemagglutinin HA 0.0035
6566 Hemagglutinin Not Available 0.0035
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0032
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0032
2297 Genome polyprotein Not Available 0.0032
2322 Genome polyprotein Not Available 0.0032
2694 Genome polyprotein Not Available 0.0032
2719 Genome polyprotein Not Available 0.0032
2860 Genome polyprotein Not Available 0.0032
2928 Genome polyprotein Not Available 0.0032
3160 Genome polyprotein Not Available 0.0032
3260 Genome polyprotein Not Available 0.0032
4783 Genome polyprotein Not Available 0.0032
5726 Genome polyprotein Not Available 0.0032
5779 Genome polyprotein Not Available 0.0032
5867 Genome polyprotein Not Available 0.0032
6253 Genome polyprotein Not Available 0.0032
6301 Genome polyprotein Not Available 0.0032
6380 Genome polyprotein Not Available 0.0032
6381 Genome polyprotein Not Available 0.0032
6437 Genome polyprotein Not Available 0.0032
6520 Genome polyprotein Not Available 0.0032
6521 Genome polyprotein Not Available 0.0032
6652 Genome polyprotein Not Available 0.0032
6734 Genome polyprotein Not Available 0.0032
6735 Genome polyprotein Not Available 0.0032
6736 Genome polyprotein Not Available 0.0032
6737 Genome polyprotein Not Available 0.0032
6738 Genome polyprotein Not Available 0.0032
6739 Genome polyprotein Not Available 0.0032
6744 Genome polyprotein Not Available 0.0032
6748 Genome polyprotein Not Available 0.0032
6894 Genome polyprotein Not Available 0.0032
6898 Genome polyprotein Not Available 0.0032
3140 Hemagglutinin-neuraminidase HN 0.0032
3609 Hemagglutinin-neuraminidase HN 0.0032
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0032
3444 Cyanovirin-N Not Available 0.0032
1859 Prostatic acid phosphatase ACPP 0.0032
4787 Envelope glycoprotein gp160 env 0.003
4820 Envelope glycoprotein gp160 env 0.003
5727 Envelope glycoprotein gp160 env 0.003
852 Heparin cofactor 2 SERPIND1 0.0029
554 Low-density lipoprotein receptor LDLR 0.0029
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0029
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0029
3480 Mannan endo-1,4-beta-mannosidase manA 0.0028
64 Neuraminidase NA 0.0028
641 Neuraminidase NA 0.0028
2676 Neuraminidase NA 0.0028
3026 Neuraminidase NA 0.0028
3519 Neuraminidase NA 0.0028
6007 Neuraminidase NA 0.0028
595 Fibrinogen alpha chain FGA 0.0027
1439 Lactotransferrin LTF 0.0027
1243 Cathepsin D CTSD 0.0026
958 Insulin-like growth factor 1 receptor IGF1R 0.0026
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0026
6307 Ig gamma-2 chain C region IGHG2 0.0025
6500 Phospholipase A2 PLA2G1B 0.0024
3814 Complement C1r subcomponent C1R 0.0023
2207 Rhodopsin RHO 0.0022
309 Antithrombin-III SERPINC1 0.0022
4785 Ig gamma-1 chain C region IGHG1 0.002
76 Nitric-oxide synthase, brain NOS1 0.002
952 Dipeptidyl peptidase 4 DPP4 0.0018
4604 Liver carboxylesterase 1 CES1 0.0017
3923 Cholinesterase BCHE 0.0013
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