DT-Web

DB04256 - 4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid


Identification
Name 4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid
Accession Number DB04256 (EXPT02133)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 209.1986
Groups experimental
Monoisotopic Weight 209.068807845
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Metabotropic glutamate receptor 1
Name Metabotropic glutamate receptor 1
Gene Name GRM1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6294

Predictions


Id Partner name Gene Name Score
1362 Metabotropic glutamate receptor 2 GRM2 0.0886
4096 Metabotropic glutamate receptor 3 GRM3 0.0886
2178 Metabotropic glutamate receptor 5 GRM5 0.0807
593 Proton-coupled amino acid transporter 1 SLC36A1 0.0596
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0459
927 Metabotropic glutamate receptor 8 GRM8 0.0078
926 Metabotropic glutamate receptor 7 GRM7 0.0078
925 Metabotropic glutamate receptor 4 GRM4 0.0078
4016 Excitatory amino acid transporter 5 SLC1A7 0.0078
4026 Aspartyl aminopeptidase DNPEP 0.0078
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0078
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0078
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0078
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0078
664 Glutamate decarboxylase 2 GAD2 0.0078
3890 Glutamate decarboxylase 2 GAD2 0.0078
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0078
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0078
1912 Excitatory amino acid transporter 1 SLC1A3 0.0078
4019 Excitatory amino acid transporter 4 SLC1A6 0.0078
1047 Excitatory amino acid transporter 2 SLC1A2 0.0078
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0078
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0078
4020 Glutamyl aminopeptidase ENPEP 0.0078
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0078
4018 Glutamate receptor delta-2 subunit GRID2 0.0078
4027 Glutamate receptor delta-1 subunit GRID1 0.0078
4017 5-oxoprolinase OPLAH 0.0078
922 Glutamate receptor 4 GRIA4 0.0078
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0065
5 Glutaminase liver isoform, mitochondrial GLS2 0.0065
917 Glutaminase kidney isoform, mitochondrial GLS 0.0065
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0065
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0065
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0065
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0065
5261 Phosphoribosylformylglycinamidine synthase purL 0.0065
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0064
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0063
625 Glutamate carboxypeptidase 2 FOLH1 0.0063
665 Phosphoserine aminotransferase PSAT1 0.006
4652 Phosphoserine aminotransferase serC 0.006
420 Glutamate decarboxylase 1 GAD1 0.006
3900 Glutamate decarboxylase 1 GAD1 0.006
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.006
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.006
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0059
923 Glutamate receptor 3 GRIA3 0.0057
1671 Excitatory amino acid transporter 3 SLC1A1 0.0057
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0056
3877 Growth-inhibiting protein 18 GIG18 0.0055
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0055
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0054
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0054
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0054
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0053
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0053
426 Aspartate aminotransferase, mitochondrial GOT2 0.0053
735 Alanine aminotransferase 1 GPT 0.0052
3904 Alanine aminotransferase 2 GPT2 0.0052
763 Tyrosine aminotransferase TAT 0.0052
5493 Tyrosine aminotransferase Not Available 0.0052
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0051
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0051
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.005
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.005
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0048
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0048
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0047
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0047
33 Cystine/glutamate transporter SLC7A11 0.0046
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0046
3426 Glutamine synthetase glnA 0.0046
3987 Glutamine synthetase GLUL 0.0046
705 Glutamate receptor 1 GRIA1 0.0046
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0045
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0044
738 Monocarboxylate transporter 1 SLC16A1 0.0038
6151 Monocarboxylate transporter 10 SLC16A10 0.0035
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0035
921 Glutamate receptor 2 GRIA2 0.0033
↑