DT-Web

DB04075 - N-Acetyl-L-Glutamate


Identification
Name N-Acetyl-L-Glutamate
Accession Number DB04075 (EXPT02356)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 189.1659
Groups experimental
Monoisotopic Weight 189.063722467
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Acetylglutamate kinase
Name Acetylglutamate kinase
Gene Name argB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7152
Acetylglutamate kinase
Name Acetylglutamate kinase
Gene Name argB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7152

Predictions


Id Partner name Gene Name Score
3669 Ribokinase rbsK 0.0719
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0687
6447 Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 0.0645
6395 Myosin-14 MYH14 0.061
702 UMP-CMP kinase CMPK1 0.0593
5302 TrwB trwB 0.0233
5646 Galactokinase GALK1 0.0233
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0233
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0233
5265 FtsH ftsH 0.0233
5312 Kinesin-like protein KIF1A KIF1A 0.0215
2371 Pantothenate kinase coaA 0.0203
825 Arsenical pump-driving ATPase ASNA1 0.0203
3435 Arsenical pump-driving ATPase arsA 0.0203
1881 Hexokinase-1 HK1 0.0203
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0203
2615 Chemotaxis protein cheA cheA 0.0203
2727 S-adenosylmethionine synthetase metK 0.0194
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.019
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0187
2251 Thymidylate kinase tmk 0.0168
2254 Thymidylate kinase DTYMK 0.0168
3522 Thymidylate kinase tmk 0.0168
207 Glutathione synthetase GSS 0.0165
5269 Glutathione synthetase gshB 0.0165
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0159
3822 Actin, alpha skeletal muscle ACTA1 0.0158
5287 Signaling protein Not Available 0.0146
5293 Shikimate kinase 2 aroL 0.0145
5288 Shikimate kinase aroK 0.0145
5304 UPF0166 protein TM_0021 TM_0021 0.0145
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0145
5292 Putative partitioning protein TT_C1605 0.0145
4346 Polynucleotide kinase pseT 0.0145
5266 Activator of hgdC 0.0145
3199 Phosphopantetheine adenylyltransferase coaD 0.0145
3543 Phosphopantetheine adenylyltransferase coaD 0.0145
3567 Phosphopantetheine adenylyltransferase coaD 0.0145
5289 Phosphopantetheine adenylyltransferase coaD 0.0145
5281 Plasmid segregation protein parM parM 0.0145
5283 D-alanine--D-alanine ligase B ddlB 0.0145
2874 Nitrogenase iron protein 1 nifH1 0.0145
5299 D-alanine--D-alanine ligase ddl 0.0145
6598 D-alanine--D-alanine ligase ddl 0.0145
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0145
5259 Transcriptional regulator ntrC1 0.0145
6699 Transcriptional regulator Cgl2612 0.0145
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0145
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0145
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0145
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0145
5291 Glycogen synthase 1 glgA1 0.0145
5264 DNA replication protein REP 0.0145
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0145
5276 Chromosomal replication initiator protein dnaA dnaA 0.0145
5315 Chaperone protein htpG htpG 0.0145
5277 Preprotein translocase subunit secA secA 0.0145
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0145
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0145
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0145
5261 Phosphoribosylformylglycinamidine synthase purL 0.0145
5308 Preprotein translocase secA 1 subunit secA1 0.0145
5285 Kinesin heavy chain KIF5B 0.0145
5284 Large T antigen Not Available 0.0145
1721 Glycogen synthase kinase-3 beta GSK3B 0.0145
4106 Guanylate kinase GUK1 0.0127
4516 Guanylate kinase gmk 0.0127
3470 Hypothetical protein MG245 homolog MPN_348 0.0127
2270 Dephospho-CoA kinase coaE 0.0127
2284 Adenylate kinase adk 0.0127
2296 Adenylate kinase adk 0.0127
2311 Adenylate kinase adk 0.0127
2312 Adenylate kinase Not Available 0.0127
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0127
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0127
4774 NTPase P4 Not Available 0.0127
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0126
4837 Cag-alfa cag-alfa 0.0126
3426 Glutamine synthetase glnA 0.0126
3987 Glutamine synthetase GLUL 0.0126
413 Amidophosphoribosyltransferase PPAT 0.0126
2515 Amidophosphoribosyltransferase purF 0.0126
3714 Amidophosphoribosyltransferase purF 0.0126
3175 Glutamate--cysteine ligase gshA 0.0126
4839 DNA polymerase III subunit tau dnaX 0.0126
5189 Trimethylamine dehydrogenase tmd 0.0126
6277 Heat shock cognate 71 kDa protein HSPA8 0.0126
4838 PMS1 protein homolog 2 PMS2 0.0126
5641 Rod shape-determining protein MreB TM_0588 0.0122
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0122
5649 Potassium-transporting ATPase B chain kdpB 0.0122
3794 Osmolarity sensor protein envZ envZ 0.0122
5644 Sensor protein phoQ phoQ 0.0122
5643 General secretion pathway protein E epsE 0.0122
5642 Chaperone clpB clpB 0.0122
5645 DNA topoisomerase 4 subunit B parE 0.0122
6227 DNA topoisomerase 4 subunit B parE 0.0122
2683 Mono-ADP-ribosyltransferase C3 C3 0.0117
2390 Nonsecretory ribonuclease RNASE2 0.0117
2922 Glycerol kinase glpK 0.0117
5271 Focal adhesion kinase 1 PTK2 0.0117
340 Apoptotic protease-activating factor 1 APAF1 0.0113
5300 Antigen peptide transporter 1 TAP1 0.0111
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.011
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.011
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.011
2282 Protein recA recA 0.0108
2315 Protein recA recA 0.0108
2332 Protein recA recA 0.0108
5263 Protein recA recA 0.0108
408 Riboflavin kinase RFK 0.0108
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0106
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0106
4751 Mitogen-activated protein kinase 12 MAPK12 0.0106
740 Argininosuccinate synthase ASS1 0.0106
865 Argininosuccinate synthase ASS1 0.0106
2680 Argininosuccinate synthase argG 0.0106
3194 Argininosuccinate synthase argG 0.0106
2397 Dihydroxyacetone kinase dhaK 0.0106
2852 DNA mismatch repair protein mutL mutL 0.0106
788 Creatine kinase M-type CKM 0.0104
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0104
2334 Dethiobiotin synthetase bioD 0.0102
6555 Dethiobiotin synthetase bioD 0.0102
2697 Uridine-cytidine kinase 2 UCK2 0.0102
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0099
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0099
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0099
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0098
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0098
3231 Death-associated protein kinase 1 DAPK1 0.0098
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0098
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0096
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0094
48 Pyridoxal kinase PDXK 0.0093
2091 Endoplasmin HSP90B1 0.0093
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0092
1422 Serine/threonine-protein kinase 6 AURKA 0.009
887 DNA gyrase subunit B gyrB 0.0089
4150 DNA gyrase subunit B gyrB 0.0089
6225 DNA gyrase subunit B gyrB 0.0089
3379 Kinesin-like protein KIF11 KIF11 0.0088
936 Ephrin type-A receptor 2 EPHA2 0.0088
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0087
504 Mast/stem cell growth factor receptor KIT 0.0083
509 Thymidine kinase TK 0.0081
570 Thymidine kinase TK 0.0081
2559 Thymidine kinase TK 0.0081
3430 Thymidine kinase tdk 0.0081
3518 Thymidine kinase TK 0.0081
5301 Thymidine kinase tdk 0.0081
5771 Thymidine kinase ORF36 0.0081
7009 Thymidine kinase ORF36 0.0081
5294 Nucleoside diphosphate kinase A NME1 0.008
958 Insulin-like growth factor 1 receptor IGF1R 0.0079
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0074
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0074
5682 Ribonuclease pancreatic RNASE1 0.0074
4192 DNA topoisomerase 2-beta TOP2B 0.0073
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0071
4773 Deoxycytidine kinase DCK 0.0071
1836 Mitogen-activated protein kinase 10 MAPK10 0.0069
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0067
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0066
2236 Casein kinase II subunit alpha CSNK2A1 0.0065
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