DT-Web

DB04069 - 5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine


Identification
Name 5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine
Accession Number DB04069 (EXPT01270)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 197.2358
Groups experimental
Monoisotopic Weight 197.095297367
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Death-associated protein kinase 1
Name Death-associated protein kinase 1
Gene Name DAPK1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3478

Predictions


Id Partner name Gene Name Score
3794 Osmolarity sensor protein envZ envZ 0.0154
5649 Potassium-transporting ATPase B chain kdpB 0.0154
5644 Sensor protein phoQ phoQ 0.0154
5641 Rod shape-determining protein MreB TM_0588 0.0154
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0154
5642 Chaperone clpB clpB 0.0154
5643 General secretion pathway protein E epsE 0.0154
5645 DNA topoisomerase 4 subunit B parE 0.0154
6227 DNA topoisomerase 4 subunit B parE 0.0154
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0154
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0154
2282 Protein recA recA 0.0134
2315 Protein recA recA 0.0134
2332 Protein recA recA 0.0134
5263 Protein recA recA 0.0134
4751 Mitogen-activated protein kinase 12 MAPK12 0.0134
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0134
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0134
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0134
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0134
5302 TrwB trwB 0.0134
5646 Galactokinase GALK1 0.0134
2852 DNA mismatch repair protein mutL mutL 0.0134
740 Argininosuccinate synthase ASS1 0.0134
865 Argininosuccinate synthase ASS1 0.0134
2680 Argininosuccinate synthase argG 0.0134
3194 Argininosuccinate synthase argG 0.0134
2397 Dihydroxyacetone kinase dhaK 0.0134
5265 FtsH ftsH 0.0134
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0123
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0123
5312 Kinesin-like protein KIF1A KIF1A 0.0123
2371 Pantothenate kinase coaA 0.0116
1881 Hexokinase-1 HK1 0.0116
2892 Acetylglutamate kinase argB 0.0116
3550 Acetylglutamate kinase argB 0.0116
825 Arsenical pump-driving ATPase ASNA1 0.0116
3435 Arsenical pump-driving ATPase arsA 0.0116
2615 Chemotaxis protein cheA cheA 0.0116
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0116
2727 S-adenosylmethionine synthetase metK 0.0111
887 DNA gyrase subunit B gyrB 0.011
4150 DNA gyrase subunit B gyrB 0.011
6225 DNA gyrase subunit B gyrB 0.011
936 Ephrin type-A receptor 2 EPHA2 0.0108
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0107
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0106
958 Insulin-like growth factor 1 receptor IGF1R 0.0099
2251 Thymidylate kinase tmk 0.0095
2254 Thymidylate kinase DTYMK 0.0095
3522 Thymidylate kinase tmk 0.0095
3822 Actin, alpha skeletal muscle ACTA1 0.0091
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0089
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0087
1836 Mitogen-activated protein kinase 10 MAPK10 0.0087
4192 DNA topoisomerase 2-beta TOP2B 0.0086
207 Glutathione synthetase GSS 0.0086
5269 Glutathione synthetase gshB 0.0086
1721 Glycogen synthase kinase-3 beta GSK3B 0.0083
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0082
2236 Casein kinase II subunit alpha CSNK2A1 0.0081
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