DT-Web

DB03926 - 5-Alpha-Androstane-3-Beta,17-Alpha-Diol


Identification
Name 5-Alpha-Androstane-3-Beta,17-Alpha-Diol
Accession Number DB03926 (EXPT00531)
Type small molecule
Description The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 292.4562
Groups experimental
Monoisotopic Weight 292.240230268
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Carriers


Predictions


Id Partner name Gene Name Score
146 Androgen receptor AR 0.0785
3811 Cytochrome P450 19A1 CYP19A1 0.0555
869 Estrogen receptor beta ESR2 0.0553
136 Estrogen receptor ESR1 0.0349
269 Adrenodoxin, mitochondrial FDX1 0.0348
381 Prolactin receptor PRLR 0.0347
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0284
4512 Cytochrome P450 3A4 CYP3A4 0.0268
587 Serum albumin ALB 0.0244
614 Progesterone receptor PGR 0.0237
232 Corticosteroid-binding globulin SERPINA6 0.0229
871 Glucocorticoid receptor NR3C1 0.0224
1588 Multidrug resistance protein 1 ABCB1 0.0196
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0186
1649 Small inducible cytokine A2 CCL2 0.0167
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0163
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0155
380 Cytochrome P450 17A1 CYP17A1 0.0154
6107 Cytochrome P450 3A7 CYP3A7 0.0151
4118 Cytochrome P450 3A5 CYP3A5 0.0143
226 Gonadotropin-releasing hormone receptor GNRHR 0.0136
6145 Solute carrier family 22 member 1 SLC22A1 0.012
6142 Solute carrier family 22 member 8 SLC22A8 0.0118
469 Annexin A1 ANXA1 0.0112
6016 Cytochrome P450 2C19 CYP2C19 0.0095
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0093
4757 Cytochrome P450 2C9 CYP2C9 0.009
6030 Cytochrome P450 2B6 CYP2B6 0.0089
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0086
4924 Cytochrome P450 2C8 CYP2C8 0.0078
4200 Cytochrome P450 1A2 CYP1A2 0.0074
6147 Solute carrier family 22 member 3 SLC22A3 0.0052
1898 Cytochrome P450 1B1 CYP1B1 0.0052
6014 Cytochrome P450 2A13 CYP2A13 0.0046
6024 Cytochrome P450 1A1 CYP1A1 0.0041
6085 Fatty acid-binding protein, intestinal FABP2 0.0036
6141 Sodium/bile acid cotransporter SLC10A1 0.0035
6031 Cytochrome P450 3A43 CYP3A43 0.0035
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0032
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0031
833 Organic cation/carnitine transporter 1 SLC22A4 0.0028
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0028
3941 Amine oxidase [flavin-containing] A MAOA 0.0027
6148 Multidrug resistance-associated protein 7 ABCC10 0.0027
6143 Solute carrier family 22 member 7 SLC22A7 0.0026
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0025
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0025
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0024
1024 Solute carrier family 22 member 11 SLC22A11 0.0023
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0021
6144 Solute carrier family 22 member 2 SLC22A2 0.0021
↑