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DB03546 - 10-CF3C(OH)2-DDACTHF


Identification
Name 10-CF3C(OH)2-DDACTHF
Accession Number DB03546 (EXPT01969)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 549.4975
Groups experimental
Monoisotopic Weight 549.204647576
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase
Name Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase
Gene Name GART
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.882

Predictions


Id Partner name Gene Name Score
2689 Phosphoribosylglycinamide formyltransferase purN 0.1637
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.1472
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0641
365 Dihydrofolate reductase DHFR 0.0499
2381 Dihydrofolate reductase DFR1 0.0499
2833 Dihydrofolate reductase Not Available 0.0499
2931 Dihydrofolate reductase folA 0.0499
3544 Dihydrofolate reductase folA 0.0499
3682 Dihydrofolate reductase folA 0.0499
6642 Dihydrofolate reductase folA 0.0499
6756 Dihydrofolate reductase dfrA 0.0499
24 Thymidylate synthase TMP1 0.0498
359 Thymidylate synthase TYMS 0.0498
2626 Thymidylate synthase thyA 0.0498
2729 Thymidylate synthase thyA 0.0498
5352 Thymidylate synthase THYA 0.0498
4773 Deoxycytidine kinase DCK 0.0495
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0491
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