DT-Web

DB03541 - 10-Propargyl-5,8-Dideazafolic Acid


Identification
Name 10-Propargyl-5,8-Dideazafolic Acid
Accession Number DB03541 (EXPT00839)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 477.4693
Groups experimental
Monoisotopic Weight 477.164833493
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Thymidylate synthase
Name Thymidylate synthase
Gene Name THYA
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.8205
Thymidylate synthase
Name Thymidylate synthase
Gene Name thyA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8205
Thymidylate synthase
Name Thymidylate synthase
Gene Name thyA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8205
Ribosyldihydronicotinamide dehydrogenase [quinone]
Name Ribosyldihydronicotinamide dehydrogenase [quinone]
Gene Name NQO2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8506
Thymidylate synthase
Name Thymidylate synthase
Gene Name TYMS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8205
Putative dehydrogenase/reductase SDR family member 4-like 2
Name Putative dehydrogenase/reductase SDR family member 4-like 2
Gene Name DHRS4L1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
24 Thymidylate synthase TMP1 0.8205
2567 Thymidylate synthase thyX thyX 0.2188
2410 Deoxyuridine 5'-triphosphate nucleotidohydrolase dut 0.1427
2490 Deoxyuridine 5'-triphosphate nucleotidohydrolase dut 0.1427
2555 Pol polyprotein pol 0.1307
3242 Pol polyprotein gag-pol 0.1307
3471 Pol polyprotein gag-pro-pol 0.1307
5256 Pol polyprotein pol 0.1307
6469 Pol polyprotein gag-pol 0.1307
6565 Pol polyprotein Not Available 0.1307
5435 Deoxycytidylate 5-hydroxymethyltransferase 42 0.1243
3586 Thymidylate synthase A thyA1 0.0984
2717 Folylpolyglutamate synthase fgs 0.0934
3639 Thymidine phosphorylase deoA 0.0784
3936 Thymidine phosphorylase TYMP 0.0784
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0745
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.068
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.068
3596 Deoxynucleotide monophosphate kinase 1 0.0625
2617 Nitric oxide synthase oxygenase nos 0.0577
2701 Nitric oxide synthase oxygenase nos 0.0577
365 Dihydrofolate reductase DHFR 0.0447
2381 Dihydrofolate reductase DFR1 0.0447
2833 Dihydrofolate reductase Not Available 0.0447
2931 Dihydrofolate reductase folA 0.0447
3544 Dihydrofolate reductase folA 0.0447
3682 Dihydrofolate reductase folA 0.0447
6642 Dihydrofolate reductase folA 0.0447
6756 Dihydrofolate reductase dfrA 0.0447
2257 Uridine phosphorylase udp 0.0447
5132 Uridine phosphorylase udp 0.0447
4275 PCZA361.16 Not Available 0.0343
4276 DNA polymerase III subunit epsilon dnaQ 0.0343
1353 DNA topoisomerase 1 TOP1 0.0318
3552 DNA topoisomerase 1 topA 0.0318
2251 Thymidylate kinase tmk 0.0278
2254 Thymidylate kinase DTYMK 0.0278
3522 Thymidylate kinase tmk 0.0278
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0276
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0276
4680 Amicyanin mauC 0.0251
3529 Interferon-stimulated gene 20 kDa protein ISG20 0.0249
3575 Uracil phosphoribosyltransferase upp 0.0249
3600 Uracil phosphoribosyltransferase upp 0.0249
3056 Orotidine 5'-phosphate decarboxylase pyrF 0.0249
3564 Orotidine 5'-phosphate decarboxylase pyrF 0.0249
4604 Liver carboxylesterase 1 CES1 0.0248
509 Thymidine kinase TK 0.0234
570 Thymidine kinase TK 0.0234
2559 Thymidine kinase TK 0.0234
3430 Thymidine kinase tdk 0.0234
3518 Thymidine kinase TK 0.0234
5301 Thymidine kinase tdk 0.0234
5771 Thymidine kinase ORF36 0.0234
7009 Thymidine kinase ORF36 0.0234
3611 Cytidine deaminase cdd 0.0234
3707 Cytidine deaminase cdd 0.0234
4211 Cytidine deaminase CDA 0.0234
3747 Cellulase B precursor celB 0.0231
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0231
4681 Aminopeptidase Not Available 0.0231
2320 Thymidine kinase, cytosolic TK1 0.0231
1898 Cytochrome P450 1B1 CYP1B1 0.0221
2344 Ribosomal small subunit pseudouridine synthase A rsuA 0.0215
3706 Ribosomal small subunit pseudouridine synthase A rsuA 0.0215
3257 Bifunctional polymyxin resistance protein arnA arnA 0.0214
4228 Keratin, type II cytoskeletal 7 KRT7 0.0213
6024 Cytochrome P450 1A1 CYP1A1 0.0211
6513 Urease subunit gamma ureA 0.0206
6512 Urease subunit beta ureB 0.0205
6511 Urease subunit alpha ureC 0.0205
6514 Probable rRNA methylase TTHA1387 0.0205
2590 Galactose-1-phosphate uridylyltransferase galT 0.0199
2966 PyrR bifunctional protein [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase pyrR 0.0198
4200 Cytochrome P450 1A2 CYP1A2 0.0197
4773 Deoxycytidine kinase DCK 0.0196
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0195
4272 POSSIBLE CELLULASE CELA1 celA1 0.0192
1588 Multidrug resistance protein 1 ABCB1 0.0187
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0184
5691 DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC rmlC 0.018
3361 Serpin B5 SERPINB5 0.018
5694 Transcription antiterminator licT licT 0.018
2164 Multidrug resistance-associated protein 4 ABCC4 0.0172
54 Prothrombin F2 0.0167
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.0166
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0165
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0165
1043 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase GART 0.0165
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0163
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.016
4757 Cytochrome P450 2C9 CYP2C9 0.016
4512 Cytochrome P450 3A4 CYP3A4 0.0157
56 Delta-aminolevulinic acid dehydratase ALAD 0.0144
2356 Delta-aminolevulinic acid dehydratase hemB 0.0144
3613 Delta-aminolevulinic acid dehydratase hemB 0.0144
3674 Delta-aminolevulinic acid dehydratase hemB 0.0144
2286 Isocitrate dehydrogenase [NADP] icd 0.0136
2302 Isocitrate dehydrogenase [NADP] icd 0.0136
2771 Isocitrate dehydrogenase [NADP] icd 0.0136
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0132
4534 Cytohesin-2 CYTH2 0.013
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0126
3668 Maltose-binding periplasmic protein precursor malE 0.0126
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0125
1729 Solute carrier family 22 member 6 SLC22A6 0.0116
2236 Casein kinase II subunit alpha CSNK2A1 0.0115
2592 Beta-galactosidase lacZ 0.0112
315 Arginase-1 ARG1 0.0106
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0106
3917 Methylenetetrahydrofolate reductase MTHFR 0.0106
702 UMP-CMP kinase CMPK1 0.0098
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0097
373 Transthyretin TTR 0.0097
3830 Calreticulin CALR 0.0088
6148 Multidrug resistance-associated protein 7 ABCC10 0.0088
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0087
6034 Hydroxyindole O-methyltransferase ASMT 0.0086
6035 Nuclear receptor ROR-beta RORB 0.0086
6036 Eosinophil peroxidase EPX 0.0086
6171 Solute carrier family 28 member 3 SLC28A3 0.0085
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0085
4924 Cytochrome P450 2C8 CYP2C8 0.0083
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0081
400 Coagulation factor IX F9 0.008
5461 Coagulation factor IX F9 0.008
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0075
604 Vitamin K-dependent protein Z PROZ 0.0075
765 Indoleamine 2,3-dioxygenase IDO1 0.0074
571 Melatonin receptor type 1A MTNR1A 0.0074
362 Melatonin receptor type 1B MTNR1B 0.0074
290 Prostaglandin G/H synthase 2 PTGS2 0.0072
6020 Aldehyde oxidase AOX1 0.007
20 Prostaglandin G/H synthase 1 PTGS1 0.0068
4119 Cytochrome P450 2D6 CYP2D6 0.0067
422 Vitamin K-dependent protein C PROC 0.0067
1245 Vitamin K-dependent protein S PROS1 0.0067
5669 50S ribosomal protein L27 rpmA 0.0065
5670 Organic hydroperoxide resistance protein ohr 0.0065
5675 Chaperone protein torD torD 0.0065
5672 Molybdenum cofactor biosynthesis protein A moaA 0.0065
5410 Unsaturated glucuronyl hydrolase ugl 0.0065
5676 Axin-1 AXIN1 0.0065
5673 C protein alpha-antigen bca 0.0065
798 Osteocalcin BGLAP 0.0064
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0062
4226 Uridine phosphorylase 2 UPP2 0.0061
369 Coagulation factor VII F7 0.0059
4225 Uridine phosphorylase 1 UPP1 0.0059
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0059
3317 Holo-[acyl-carrier-protein] synthase acpS 0.0057
4381 Holo-[acyl-carrier-protein] synthase acpS 0.0057
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.0057
2636 Shikimate dehydrogenase aroE 0.0057
3515 Shikimate dehydrogenase aroE 0.0057
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0057
5718 Cytochrome P450 2A6 CYP2A6 0.0056
3947 Xanthine dehydrogenase/oxidase XDH 0.0056
2280 Listeriolysin regulatory protein prfA 0.0052
4811 Amylosucrase ams 0.0052
6579 Calcium/calmodulin-dependent protein kinase type II alpha chain CAMK2A 0.0052
413 Amidophosphoribosyltransferase PPAT 0.0051
2515 Amidophosphoribosyltransferase purF 0.0051
3714 Amidophosphoribosyltransferase purF 0.0051
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.005
6142 Solute carrier family 22 member 8 SLC22A8 0.005
3191 Histidinol dehydrogenase hisD 0.0049
465 Calmodulin CALM1 0.0048
191 Peptide methionine sulfoxide reductase MSRA 0.0047
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.0047
909 Maleylacetoacetate isomerase GSTZ1 0.0046
1757 Myeloperoxidase MPO 0.0046
239 Coagulation factor X F10 0.0046
6143 Solute carrier family 22 member 7 SLC22A7 0.0045
611 Retinal dehydrogenase 1 ALDH1A1 0.0044
136 Estrogen receptor ESR1 0.0041
2314 Triosephosphate isomerase TPI 0.004
3417 Triosephosphate isomerase tpiA 0.004
3443 Triosephosphate isomerase tpiA 0.004
6346 Triosephosphate isomerase TPI1 0.004
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.004
3811 Cytochrome P450 19A1 CYP19A1 0.0039
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0037
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0037
5818 Folate receptor alpha FOLR1 0.0037
587 Serum albumin ALB 0.0036
6136 Multidrug resistance-associated protein 5 ABCC5 0.0033
293 Gamma-glutamyl hydrolase GGH 0.0032
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0029
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0029
1650 Heme carrier protein 1 SLC46A1 0.0029
6013 Cytochrome P450 2E1 CYP2E1 0.0028
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0028
6016 Cytochrome P450 2C19 CYP2C19 0.0028
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0025
5095 Putidaredoxin reductase camA 0.0025
526 Thioredoxin reductase trxB 0.0025
3767 Thioredoxin reductase trxB 0.0025
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0025
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0025
5122 Mersacidin decarboxylase mrsD 0.0025
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0025
5115 FkbI fkbI 0.0025
3133 UDP-galactopyranose mutase glf 0.0025
5099 UDP-galactopyranose mutase glf 0.0025
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0025
5083 Cryptochrome DASH cry 0.0025
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0025
3763 5,10-methylenetetrahydrofolate reductase metF 0.0025
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0025
5094 5,10-methylenetetrahydrofolate reductase metF 0.0025
5078 Amine oxidase, flavin-containing PSPTO1126 0.0025
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0025
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0025
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0025
5081 L-aspartate oxidase nadB 0.0025
5111 Phenylacetone monooxygenase pamO 0.0025
1410 Oxidoreductase HSD17B6 0.0025
4725 Oxidoreductase Not Available 0.0025
5124 Oxidoreductase Not Available 0.0025
5109 Outer membrane protein p64k or PM-6 m-6 0.0025
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0023
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0023
4486 Phenol 2-hydroxylase component B pheA2 0.0023
4477 Dihydrolipoyl dehydrogenase lpdV 0.0023
5077 Dihydrolipoyl dehydrogenase Not Available 0.0023
5117 Dihydrolipoyl dehydrogenase lpd 0.0023
4439 Ferredoxin reductase bphA4 0.0023
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0022
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0021
5073 Ferredoxin--NADP reductase petH 0.0021
5076 Ferredoxin--NADP reductase fpr 0.0021
5119 Ferredoxin--NADP reductase petH 0.0021
5121 Ferredoxin--NADP reductase fpr 0.0021
2526 NADPH-ferredoxin reductase fprA fprA 0.0021
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0021
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0021
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0021
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0021
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0021
3594 Deoxyribodipyrimidine photo-lyase phr 0.0021
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0021
5080 Deoxyribodipyrimidine photo-lyase phr 0.0021
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0021
5072 N,N-dimethylglycine oxidase dmg 0.0021
2470 Pyruvate oxidase pox5 0.0021
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0021
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0021
2268 Cholesterol oxidase choB 0.0021
2822 Cholesterol oxidase choA 0.0021
714 Glutathione reductase, mitochondrial GSR 0.0021
3102 Flavohemoprotein hmp 0.002
4969 Flavohemoprotein hmp 0.002
4440 NADH peroxidase npr 0.002
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.002
738 Monocarboxylate transporter 1 SLC16A1 0.002
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.002
2893 Glycine oxidase thiO 0.0019
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0019
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0019
327 Glutathione reductase gor 0.0019
5110 Glutathione reductase GR2 0.0019
2823 Trypanothione reductase TPR 0.0018
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0018
126 D-lactate dehydrogenase dld 0.0018
3545 D-lactate dehydrogenase Not Available 0.0018
4510 D-lactate dehydrogenase ldhA 0.0018
2769 P-hydroxybenzoate hydroxylase pobA 0.0018
2809 P-hydroxybenzoate hydroxylase pobA 0.0018
605 Fumarate reductase flavoprotein subunit frdA 0.0018
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0018
3673 Fumarate reductase flavoprotein subunit fccA 0.0018
4912 Fumarate reductase flavoprotein subunit ifcA 0.0018
6549 Fumarate reductase flavoprotein subunit frdA 0.0018
1024 Solute carrier family 22 member 11 SLC22A11 0.0017
2380 Monomeric sarcosine oxidase soxA 0.0017
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0016
6645 D-amino-acid oxidase DAO 0.0016
862 Multidrug resistance-associated protein 1 ABCC1 0.0016
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0016
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0015
76 Nitric-oxide synthase, brain NOS1 0.0012
4120 NADPH--cytochrome P450 reductase POR 0.0012
816 Biliverdin reductase A BLVRA 0.0011
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0011
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0011
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0011
3939 Amine oxidase [flavin-containing] B MAOB 0.001
646 Malate dehydrogenase, cytoplasmic MDH1 0.001
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.001
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.001
328 Sorbitol dehydrogenase SORD 0.001
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.001
666 NADP-dependent malic enzyme ME1 0.001
597 Dihydropteridine reductase QDPR 0.001
363 NADP-dependent malic enzyme, mitochondrial ME3 0.001
396 Alcohol dehydrogenase 4 ADH4 0.001
857 Malate dehydrogenase, mitochondrial MDH2 0.001
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.001
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.001
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.001
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.001
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.001
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.001
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.001
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.001
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.001
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.001
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.001
602 Acyl carrier protein, mitochondrial NDUFAB1 0.001
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.001
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.001
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.001
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.001
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.001
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.001
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.001
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.001
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.001
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.001
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.001
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.001
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.001
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.001
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.001
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.001
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.001
107 C-4 methylsterol oxidase SC4MOL 0.001
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.001
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.001
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.001
711 UDP-glucose 6-dehydrogenase UGDH 0.001
3672 UDP-glucose 6-dehydrogenase hasB 0.001
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.001
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.001
167 L-lactate dehydrogenase C chain LDHC 0.001
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.001
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.001
206 3-keto-steroid reductase HSD17B7 0.001
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.001
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.001
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.001
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.001
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.001
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.001
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.001
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.001
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.001
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.001
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.001
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.001
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.001
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.001
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.001
34 7-dehydrocholesterol reductase DHCR7 0.001
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.001
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.001
3726 D-3-phosphoglycerate dehydrogenase serA 0.001
4291 D-3-phosphoglycerate dehydrogenase serA 0.001
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.001
644 Heme oxygenase 2 HMOX2 0.001
4982 Heme oxygenase 2 pbsA2 0.001
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.001
729 GDP-L-fucose synthetase TSTA3 0.001
3463 GDP-L-fucose synthetase fcl 0.001
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.001
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.001
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.001
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.001
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.001
643 Peroxisomal bifunctional enzyme EHHADH 0.001
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.001
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.001
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.001
662 Fatty aldehyde dehydrogenase ALDH3A2 0.001
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.001
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.001
11 NAD(P) transhydrogenase, mitochondrial NNT 0.001
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.001
77 L-lactate dehydrogenase B chain LDHB 0.001
12 Alcohol dehydrogenase class 3 ADH5 0.001
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.001
3941 Amine oxidase [flavin-containing] A MAOA 0.001
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0009
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0009
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0009
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0009
473 L-lactate dehydrogenase A chain LDHA 0.0009
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0009
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0009
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0009
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0009
13 Aminomethyltransferase, mitochondrial AMT 0.0009
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0009
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0009
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0009
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0008
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0008
6026 Alcohol dehydrogenase 6 ADH6 0.0008
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0008
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0008
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0008
654 Flavin reductase BLVRB 0.0008
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0008
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0008
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0008
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0008
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0008
627 11-cis retinol dehydrogenase RDH5 0.0008
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0008
626 Cysteine dioxygenase type 1 CDO1 0.0008
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0008
569 Retinal dehydrogenase 2 ALDH1A2 0.0008
251 Alcohol dehydrogenase 1A ADH1A 0.0008
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0008
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0008
810 Heme oxygenase 1 HMOX1 0.0008
3391 Heme oxygenase 1 pbsA1 0.0008
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0008
444 Alcohol dehydrogenase 1B ADH1B 0.0008
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0007
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0007
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0007
279 Tyrosinase TYR 0.0007
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0007
380 Cytochrome P450 17A1 CYP17A1 0.0007
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0007
517 Alcohol dehydrogenase 1C ADH1C 0.0007
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0007
822 Aldose reductase AKR1B1 0.0007
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0006
468 Cytochrome P450 4A11 CYP4A11 0.0006
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